Search Results - "Fowler, D. H."

Determinants of functional performance in long-term survivors of allogeneic hematopoietic stem cell transplantation with chronic graft-versus-host disease (cGVHD) by Mitchell, S A, Leidy, N Kline, Mooney, K H, Dudley, W N, Beck, S L, LaStayo, P C, Cowen, E W, Palit, P, Comis, L E, Krumlauf, M C, Avila, D N, Atlam, N, Fowler, D H, Pavletic, S Z

“…This study examined factors accounting for functional performance limitations in 100 long-term survivors of allogeneic hematopoietic stem cell transplantation…”
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NIH response criteria measures are associated with important parameters of disease severity in patients with chronic GVHD by Curtis, L M, Grkovic, L, Mitchell, S A, Steinberg, S M, Cowen, E W, Datiles, M B, Mays, J, Bassim, C, Joe, G, Comis, L E, Berger, A, Avila, D, Taylor, T, Pulanic, D, Cole, K, Baruffaldi, J, Fowler, D H, Gress, R E, Pavletic, S Z

“…Lack of standardized criteria measuring therapeutic response remains an obstacle to the development of better treatments for chronic GVHD (cGVHD). This…”
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Clinical laboratory markers of inflammation as determinants of chronic graft-versus-host disease activity and NIH global severity by Grkovic, L, Baird, K, Steinberg, S M, Williams, K M, Pulanic, D, Cowen, E W, Mitchell, S A, Hakim, F T, Martires, K J, Avila, D N, Taylor, T N, Salit, R B, Rowley, S D, Zhang, D, Fowler, D H, Bishop, M R, Gress, R E, Pavletic, S Z

“…Chronic graft-versus-host disease (cGVHD) remains a major cause of non-relapse morbidity and mortality after allogeneic hematopoietic stem cell…”
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Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation by Bishop, M.R., Dean, R.M., Steinberg, S.M., Odom, J., Pavletic, S.Z., Chow, C., Pittaluga, S., Sportes, C., Hardy, N.M., Gea-Banacloche, J., Kolstad, A., Gress, R.E., Fowler, D.H.

“…A graft-versus-lymphoma effect against diffuse large B-cell lymphoma (DLBCL) is inferred by sustained relapse-free survival after allogeneic stem-cell…”
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Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2 neu overexpressing tumor model by Felizardo, T C, Wang, J C M, McGray, R A J, Evelegh, C, Spaner, D E, Fowler, D H, Bramson, J L, Medin, J A

“…Recent investigations have demonstrated that adenoviral and lentiviral vectors encoding HER-2 can be utilized in cancer immunotherapy. However, it is not known…”
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Chronic graft-versus-host disease in the era of reduced-intensity conditioning by SUBRAMANIAM, D. S, FOWLER, D. H, PAVLETIC, S. Z

“…In the past decade the field of hematopoietic stem cell transplantation has entered a new era with the introduction of reduced intensity conditioning (RIC)…”
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Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation by Fløisand, Y, Brinch, L, Gedde-Dahl, T, Tjønnfjord, G E, Dybedal, I, Holte, H, Heldal, D, Torfoss, D, Aurlien, E, Lauritzsen, G F, Fosså, A, Lehne, G, Baggerød, E, Kvalheim, G, Egeland, T, Bishop, M R, Fowler, D H, Kolstad, A

“…Reduced-intensity conditioning (RIC) allo-SCT is a potentially curative treatment approach for patients with relapsed Hodgkin’s or non-Hodgkin’s lymphoma. In…”
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Neoantigen and tumor antigen-specific immunity transferred from immunized donors is detectable early after allogeneic transplantation in myeloma patients by Foglietta, M, Neelapu, S S, Kwak, L W, Jiang, Y, Nattamai, D, Lee, S-T, Fowler, D H, Sportes, C, Gress, R E, Steinberg, S M, Vence, L M, Radvanyi, L, Dwyer, K C, Qazilbash, M H, Bryant, R N K, Bishop, M R

“…To enhance the therapeutic index of allogeneic hematopoietic SCT (HSCT), we immunized 10 HLA-matched sibling donors before stem cell collection with…”
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EPOCH-F: a novel salvage regimen for multiple myeloma before reduced-intensity allogeneic hematopoietic SCT by Jamshed, S, Fowler, D H, Neelapu, S S, Dean, R M, Steinberg, S M, Odom, J, Bryant, K, Hakim, F, Bishop, M R

“…There exists a need for effective salvage regimens for multiple myeloma patients being considered for reduced-intensity allogeneic hematopoietic SCT…”
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Novel application of lentiviral vectors towards treatment of graft-versus-host disease by Scaife, Matthew D, Neschadim, Anton, Fowler, D H, Medin, J A

“…Allogeneic transplantation of hematopoietic stem cells and lymphocytes is a curative treatment for malignant and non-malignant disease. However, the primary…”
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Donor CD4-Enriched Cells of Th2 Cytokine Phenotype Regulate Graft-Versus-Host Disease Without Impairing Allogeneic Engraftment in Sublethally Irradiated Mice by Fowler, Daniel H., Kurasawa, Kazuhiro, Smith, Rhett, Eckhaus, Michael A., Gress, Ronald E.

“…We have recently shown that donor CD4-enriched cells of Th2 cytokine phenotype, generated by treating mice in vivo with a combination of interleukin-2 (IL-2)…”
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Cells of Th2 cytokine phenotype prevent LPS-induced lethality during murine graft-versus-host reaction. Regulation of cytokines and CD8+ lymphoid engraftment by Fowler, DH, Kurasawa, K, Husebekk, A, Cohen, PA, Gress, RE

“…A murine parent-into-F1 graft-vs-host reaction (GVHR) model that utilizes LPS to induce lethality was used to evaluate the in vivo regulatory role of donor…”
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Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells by Symes, J C, Siatskas, C, Fowler, D H, Medin, J A

“…Adoptively transferred T cells possess anticancer activities partially mediated by T-cell FasL engagement of Fas tumor targets. However, antigen-induced T-cell…”
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Predictive models for ocular chronic graft-versus-host disease diagnosis and disease activity in transplant clinical practice by Curtis, Lauren M, Datiles, 3rd, Manuel B, Steinberg, Seth M, Mitchell, Sandra A, Bishop, Rachel J, Cowen, Edward W, Mays, Jacqueline, McCarty, John M, Kuzmina, Zoya, Pirsl, Filip, Fowler, Daniel H, Gress, Ronald E, Pavletic, Steven Z

“…Ocular chronic graft-versus-host disease is one of the most bothersome common complications following allogeneic hematopoietic stem cell transplantation. The…”
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Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes by Scaife, M, Pacienza, N, Au, B C Y, Wang, J C M, Devine, S, Scheid, E, Lee, C-J, Lopez-Perez, O, Neschadim, A, Fowler, D H, Foley, R, Medin, J A

“…Cell-fate control gene therapy (CFCGT)-based strategies can augment existing gene therapy and cell transplantation approaches by providing a safety element in…”
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In vitro generation of allospecific human CD8+ T cells of Tc1 and Tc2 phenotype by HALVERSON, D. C, SCHWARTZ, G. N, CARTER, C, GRESS, R. E, FOWLER, D. H

“…We have previously shown that allospecific murine CD8+ T cells of the Tc1 and Tc2 phenotype could be generated in vitro, and that such functionally defined…”
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Fas‐mediated lysis of chronic lymphocytic leukaemia cells: role of type I versus type II cytokines and autologous FasL‐expressing T cells by Williams, Jonathan F., Petrus, Matthew J., Wright, Jacob A., Husebekk, Anne, Fellowes, Vicki, Read, Elizabeth J., Gress, Ronald E., Fowler, Daniel H.

“…Given the known role of the fas cytolytic pathway in B‐cell regulation, we evaluated whether fas–fasL interactions might induce chronic lymphocytic leukaemia…”
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CD8+ T Cells of Tc2 Phenotype Mediate a GVL Effect and Prevent Marrow Rejection by Fowler, D.H., Gress, R.E.

“…Donor T cells mediate both beneficial and detrimental immune reactions in the setting of allogeneic BMT (alloBMT). T cells mediate the GVL effect and prevent…”
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Further Arithmetical Tables by Fowler, D. H.

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Th2 and Tc2 Cells in the Regulation of GVHD, GVL, and Graft Rejection: Considerations for the Allogeneic Transplantation Therapy of Leukemia and Lymphoma by Fowler, Daniel H., Gress, Ronald E.

“…Allogeneic stem cell transplantation (SCT) represents a curative treatment option for patients with leukemia and lymphoma. T lymphocytes contained in the…”
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