Search Results - "Fowke, Tania M."
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Modeling ischemic stroke in a triculture neurovascular unit on-a-chip
Published in Fluids and barriers of the CNS (14-12-2021)“…In ischemic stroke, the function of the cerebral vasculature is impaired. This vascular structure is formed by the so-called neurovascular unit (NVU). A better…”
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Human BBB-on-a-chip reveals barrier disruption, endothelial inflammation, and T cell migration under neuroinflammatory conditions
Published in Frontiers in molecular neuroscience (25-09-2023)“…The blood-brain barrier (BBB) is a highly selective barrier that ensures a homeostatic environment for the central nervous system (CNS). BBB dysfunction,…”
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Hyaluronan synthesis by developing cortical neurons in vitro
Published in Scientific reports (13-03-2017)“…Hyaluronan is a linear glycosaminoglycan that forms the backbone of perineuronal nets around neurons in the cerebral cortex. However, it remains controversial…”
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Connexin Hemichannel Mimetic Peptide Attenuates Cortical Interneuron Loss and Perineuronal Net Disruption Following Cerebral Ischemia in Near-Term Fetal Sheep
Published in International journal of molecular sciences (04-09-2020)“…Perinatal hypoxia-ischemia is associated with disruption of cortical gamma-aminobutyric acid (GABA)ergic interneurons and their surrounding perineuronal nets,…”
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Role of recurrent hypoxia-ischemia in preterm white matter injury severity
Published in PloS one (12-11-2014)“…Although the spectrum of white matter injury (WMI) in preterm infants is shifting from cystic necrotic lesions to milder forms, the factors that contribute to…”
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Loss of interneurons and disruption of perineuronal nets in the cerebral cortex following hypoxia-ischaemia in near-term fetal sheep
Published in Scientific reports (06-12-2018)“…Hypoxia-ischaemia (HI) in term infants is a common cause of brain injury and neurodevelopmental impairment. Development of gamma-aminobutyric acid (GABA)ergic…”
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