Search Results - "Fournel, Ludovic"

Interconnection between Metabolism and Cell Cycle in Cancer by Icard, Philippe, Fournel, Ludovic, Wu, Zherui, Alifano, Marco, Lincet, Hubert

“…Cell cycle progression and division is regulated by checkpoint controls and sequential activation of cyclin-dependent kinases (CDKs). Understanding of how…”
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ATP citrate lyase: A central metabolic enzyme in cancer by Icard, Philippe, Wu, Zherui, Fournel, Ludovic, Coquerel, Antoine, Lincet, Hubert, Alifano, Marco

“…ACLY links energy metabolism provided by catabolic pathways to biosynthesis. ACLY, which has been found to be overexpressed in many cancers, converts citrate…”
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Cisplatin increases PD-L1 expression and optimizes immune check-point blockade in non-small cell lung cancer by Fournel, Ludovic, Wu, Zherui, Stadler, Nicolas, Damotte, Diane, Lococo, Filippo, Boulle, Geoffroy, Ségal-Bendirdjian, Evelyne, Bobbio, Antonio, Icard, Philippe, Trédaniel, Jean, Alifano, Marco, Forgez, Patricia

“…The number of clinical protocols testing combined therapies including immune check-point inhibitors and platinum salts is currently increasing in lung cancer…”
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Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update by Icard, Philippe, Coquerel, Antoine, Wu, Zherui, Gligorov, Joseph, Fuks, David, Fournel, Ludovic, Lincet, Hubert, Simula, Luca

“…Citrate plays a central role in cancer cells’ metabolism and regulation. Derived from mitochondrial synthesis and/or carboxylation of α-ketoglutarate, it is…”
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Updated Prognostic Factors in Localized NSCLC by Garinet, Simon, Wang, Pascal, Mansuet-Lupo, Audrey, Fournel, Ludovic, Wislez, Marie, Blons, Hélène

“…Lung cancer is the most common cause of cancer mortality worldwide, and non-small cell lung cancer (NSCLC) represents 80% of lung cancer subtypes. Patients…”
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Subsolid Lung Nodule Classification: A CT Criterion for Improving Interobserver Agreement by Revel, Marie-Pierre, Mannes, Inès, Benzakoun, Joseph, Guinet, Claude, Léger, Thomas, Grenier, Philippe, Lupo, Audrey, Fournel, Ludovic, Chassagnon, Guillaume, Bommart, Sébastien

“…Purpose To evaluate an objective computed tomographic (CT) criterion for distinguishing between part-solid (PS) and nonsolid (NS) lung nodules. Materials and…”
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Sarcopenia as independent risk factor of postpneumonectomy respiratory failure, ARDS and mortality by Martini, Katharina, Chassagnon, Guillaume, Fournel, Ludovic, Prieto, Mathilde, Hoang-Thi, Trieu-Nghi, Halm, Nara, Bobbio, Antonio, Revel, Marie-Pierre, Alifano, Marco

“…•Sarcopenia is associated with short-term outcome in pneumonectomy.•Similarly, right side of pneumonectomy was associated with short-term outcome.•Muscle…”
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Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions by Russick, Jules, Joubert, Pierre-Emmanuel, Gillard-Bocquet, Mélanie, Torset, Carine, Meylan, Maxime, Petitprez, Florent, Dragon-Durey, Marie-Agnes, Marmier, Solenne, Varthaman, Aditi, Josseaume, Nathalie, Germain, Claire, Goc, Jérémy, Dieu-Nosjean, Marie-Caroline, Validire, Pierre, Fournel, Ludovic, Zitvogel, Laurence, Bindea, Gabriela, Lupo, Audrey, Damotte, Diane, Alifano, Marco, Cremer, Isabelle

“…BackgroundNatural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact…”
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Impact of integrating objective structured clinical examination into academic student assessment: Large-scale experience in a French medical school by Matet, Alexandre, Fournel, Ludovic, Gaillard, François, Amar, Laurence, Arlet, Jean-Benoit, Baron, Stéphanie, Bats, Anne-Sophie, Buffel du Vaure, Celine, Charlier, Caroline, De Lastours, Victoire, Faye, Albert, Jablon, Eve, Kadlub, Natacha, Leguen, Julien, Lebeaux, David, Malmartel, Alexandre, Mirault, Tristan, Planquette, Benjamin, Régent, Alexis, Thebault, Jean-Laurent, Dinh, Alexy Tran, Nuzzo, Alexandre, Turc, Guillaume, Friedlander, Gérard, Ruszniewski, Philippe, Badoual, Cécile, Ranque, Brigitte, Oualha, Mehdi, Courbebaisse, Marie

“…Objective structured clinical examinations (OSCE) evaluate clinical reasoning, communication skills, and interpersonal behavior during medical education. In…”
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Citrate targets FBPase and constitutes an emerging novel approach for cancer therapy by Icard, Philippe, Fournel, Ludovic, Coquerel, Antoine, Gligorov, Joseph, Alifano, Marco, Lincet, Hubert

“…Gao-Min Liu and Yao-Ming Zhang recently published a review entitled «Targeting FBPase is an emerging novel approach for cancer therapy» (Liu and Zhang in…”
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Surgical management of pulmonary large cell neuroendocrine carcinomas: a 10-year experience by Fournel, Ludovic, Falcoz, Pierre Emmanuel, Alifano, Marco, Charpentier, Marie-Christine, Boudaya, Mohamed-Sadok, Magdeleinat, Pierre, Damotte, Diane, Régnard, Jean-François

“…OBJECTIVES Large cell neuroendocrine carcinoma (LCNEC) represents a relatively rare and poorly studied entity whose management is not clearly established. The…”
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Totally Thoracoscopic Major Pulmonary Resections: An Analysis of Perioperative Complications by Fournel, Ludovic, MD, Zaimi, Rym, MD, Grigoroiu, Madalina, MD, Stern, Jean-Baptiste, MD, Gossot, Dominique, MD

“…Background Reports of recent large series support the safety of video-assisted thoracoscopic major pulmonary resections (MPR). However, although their rate of…”
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Time to Reach a Consensus on the Minimal Diagnostic Criteria of DIPNECH by Fournel, Ludovic

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Early and delayed post-pneumonectomy empyemas: Microbiology, management and prognosis by Stern, Jean-Baptiste, Fournel, Ludovic, Wyplosz, Benjamin, Girard, Philippe, Al Nakib, Malik, Gossot, Dominique, Seguin-Givelet, Agathe

“…Post-pneumonectomy empyema (PPE) is the most severe complication of pneumonectomy. Microbiology and its impact on management and prognosis have rarely been…”
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The key role of Warburg effect in SARS-CoV-2 replication and associated inflammatory response by Icard, Philippe, Lincet, Hubert, Wu, Zherui, Coquerel, Antoine, Forgez, Patricia, Alifano, Marco, Fournel, Ludovic

“…Current mortality due to the Covid-19 pandemic (approximately 1.2 million by November 2020) demonstrates the lack of an effective treatment. As replication of…”
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Epidemiology and prognostic factors of pleural empyema by Bobbio, Antonio, Bouam, Samir, Frenkiel, Jerome, Zarca, Kevin, Fournel, Ludovic, Canny, Emelyne, Icard, Philippe, Porcher, Raphaël, Alifano, Marco

“…Infection of the pleural cavity invariably leads to hospitalisation, and a fatal outcome is not uncommon. Our aim was to study the epidemiology of pleural…”
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Prognostic impact of inflammation in malignant pleural mesothelioma: A large-scale analysis of consecutive patients by Fournel, Ludovic, Charrier, Thomas, Huriet, Maxime, Iaffaldano, Amedeo, Lupo, Audrey, Damotte, Diane, Arrondeau, Jennifer, Alifano, Marco

“…•The prognosis of MPM is strongly and negatively influenced by systemic inflammation.•Advanced Lung cancer inflammation Index can be used as prognostic…”
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Extracellular Citrate and Cancer Metabolism-Letter by Icard, Philippe, Fournel, Ludovic, Alifano, Marco, Lincet, Hubert

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On the footsteps of Hippocrates, Sanctorius and Harvey to better understand the influence of cold on the occurrence of COVID-19 in European countries in 2020 by Icard, Philippe, Simula, Luca, Rei, Joana, Fournel, Ludovic, De Pauw, Vincent, Alifano, Marco

“…COVID-19 pandemic has been characterized by a pattern of consecutive declines and regrowth in European countries in 2020. After being partially regressed…”
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The strategic roles of four enzymes in the interconnection between metabolism and oncogene activation in non-small cell lung cancer: Therapeutic implications by Icard, Philippe, Simula, Luca, Fournel, Ludovic, Leroy, Karen, Lupo, Audrey, Damotte, Diane, Charpentier, Marie Christine, Durdux, Catherine, Loi, Mauro, Schussler, Olivier, Chassagnon, Guillaume, Coquerel, Antoine, Lincet, Hubert, De Pauw, Vincent, Alifano, Marco

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