Search Results - "Foulkes, N. S."

Zebrafish arylalkylamine-N-acetyltransferase genes – targets for regulation of the circadian clock by Appelbaum, L, Vallone, D, Anzulovich, A, Ziv, L, Tom, M, Foulkes, N S, Gothilf, Y

“…Daily rhythms of melatonin production are controlled by changes in the activity of arylalkylamine-N-acetyltransferase (AANAT). Zebrafish possess two aanats,…”
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Transcriptional Regulation of Arylalkylamine-N-Acetyltransferase-2 Gene in the Pineal Gland of the Gilthead Seabream by Zilberman-Peled, B., Appelbaum, L., Vallone, D., Foulkes, N. S., Anava, S., Anzulovich, A., Coon, S. L., Klein, D. C., Falcón, J., Ron, B., Gothilf, Y.

“…Pineal serotonin‐N‐acetyltransferase (arylalkylamine‐N‐acetyltransferase; AANAT) is considered the key enzyme in the generation of circulating melatonin…”
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Studying the Evolution of the Vertebrate Circadian Clock: The Power of Fish as Comparative Models by Foulkes, N S, Whitmore, D, Vallone, D, Bertolucci, C

“…The utility of any model species cannot be judged solely in terms of the tools and approaches it provides for genetic analysis. A fundamental consideration is…”
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Cell cycle regulation of cyclin A gene expression by the cyclic AMP-responsive transcription factors CREB and CREM by Desdouets, Chantal, Matesic, Graziella, Molina, Carlos A., Foulkes, Nicholas S., Sassone-Corsi, Paolo, Brechot, Christian, Sobczak-Thepot, Joëlle

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Relaxed selective constraints drove functional modifications in peripheral photoreception of the cavefish P. andruzzii and provide insight into the time of cave colonization by Calderoni, L, Rota-Stabelli, O, Frigato, E, Panziera, A, Kirchner, S, Foulkes, N S, Kruckenhauser, L, Bertolucci, C, Fuselli, S

“…The genetic basis of phenotypic changes in extreme environments is a key but rather unexplored topic in animal evolution. Here we provide an exemplar case of…”
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Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor by Molina, C A, Foulkes, N S, Lalli, E, Sassone-Corsi, P

“…cAMP-responsive element modulator (CREM) expression is tissue specific and developmentally regulated. Here we report that CREM is unique within the family of…”
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CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription by Foulkes, N S, Borrelli, E, Sassone-Corsi, P

“…We isolated a gene from a mouse pituitary cDNA library that encodes a protein highly homologous to nuclear factor CREB, an activator of cAMP-responsive…”
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Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland by STEHLE, J. H, FOULKES, N. S, MOLINA, C. A, SIMONNEAUX, V, PEVET, P, SASSONE-CORSI, P

“…Transcription factor CREM appears to play a key physiological and developmental role within the hypothalamic-pituitary-gonadal axis. This axis is modulated by…”
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Flies and Fish: Birds of a Feather by Katherine Tamai, T., Vardhanabhuti, V., Arthur, S., Foulkes, N. S., Whitmore, D.

“…The identification of specific clock‐containing structures has been a major endeavour of the circadian field for many years. This has lead to the…”
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Rhythmic transcription: the molecular basis of circadian melatonin synthesis by Foulkes, Nicholas S., assone-Corsi, Paolo, Borjigin, Jimo, Snyder, Solomon H., Snyder, Solomon H.

“…Adaptation to a changing environment is an essential feature of physiological regulation. The day–night rhythm is translated into hormonal oscillations…”
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Developmental switch of CREM function during spermatogenesis: from antagonist to activator by Foulkes, Nicholas S, Mellström, Britt, Benusiglio, Enrico, Sassone-Corsi, Paolo

“…Mammalian spermatogenesis consists of a series of complex developmental processes controlled by the pituitary-hypothalamic axis. This flow of biochemical…”
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Transcriptional Antagonist cAMP-Responsive Element Modulator (CREM) Down- Regulates c-fos cAMP-Induced Expression by Foulkes, Nicholas S., Laoide, Brid M., Schlotter, Florence, Sassone-Corsi, Paolo

“…Protooncogene c-fos is induced by activation of adenylate cyclase through the major cAMP-responsive element (CRE) centered at position -60 of the promoter…”
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Pituitary hormone FSH directs the CREM functional switch during spermatogenesis by Foulkes, Nicholas S, Schlotter, Florence, Pévet, Paul, Sassone-Corsi, Paolo

“…The CREM (cyclic AMP-responsive element modulator) gene encodes multiple regulators of the cAMP-transcriptional response by alternative splicing. A…”
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Pituitary Follicle-Stimulating Hormone (FSH) Induces CREM Gene Expression in Sertoli Cells: Involvement in Long-Term Desensitization of the FSH Receptor by Monaco, Lucia, Foulkes, Nicholas S., Sassone-Corsi, Paolo

“…Transcription factor CREM (cAMP-responsive element modulator) plays a pivotal role in the nuclear response to cAMP in neuroendocrine cells. We have previously…”
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Diverse Point Mutations in the Human Glucose-6-phosphate Dehydrogenase Gene Cause Enzyme Deficiency and Mild or Severe Hemolytic Anemia by Vulliamy, T. J., D'Urso, M., Battistuzzi, G., Estrada, M., Foulkes, N. S., Martini, G., Calabro, V., Poggi, V., Giordano, R., Town, M., Luzzatto, L., Persico, M. G.

“…Glucose-6-phosphate dehydrogenase (G6PD; EC 1.1.1.49) deficiency is a common genetic abnormality affecting an estimated 400 million people worldwide. Clinical…”
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The functional versatility of CREM is determined by its modular structure by Laoide, B.M., Foulkes, N.S., Schlotter, F., Sassone‐Corsi, P.

“…The CREM gene (cAMP‐responsive element modulator) generates both activators and repressors of cAMP‐induced transcription by alternative splicing. We determined…”
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Adaptive inducibility of CREM as transcriptional memory of circadian rhythms by Foulkes, Nicholas S, Duval, Gilles, Sassone-Corsi, Paolo

“…The CREM gene encodes the transcriptional repressor ICER, which has been implicated in the molecular mechanisms controlling circadian rhythms in mammals. ICER…”
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A clockwork organ by Whitmore, D, Cermakian, N, Crosio, C, Foulkes, N S, Pando, M P, Travnickova, Z, Sassone-Corsi, P

“…The vertebrate circadian clock was thought to be highly localized to specific anatomical structures: the mammalian suprachiasmatic nucleus (SCN), and the…”
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Light acts directly on organs and cells in culture to set the vertebrate circadian clock by Sassone-Corsi, Paolo, Whitmore, David, Foulkes, Nicholas S

“…The expression of clock genes in vertebrates is widespread and not restricted to classical clock structures. The expression of the Clock gene in zebrafish…”
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A potent inhibitor of Taq polymerase copurifies with human genomic DNA by DE FRENCHIS, R, CROSS, N. C. P, FOULKES, N. S, COX, T. M

“…The polymerase chain reaction (PCR) is a rapid method for amplifying a defined sequence from small amounts of input DNA. The authors have encountered a potent…”
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