Search Results - "Foulger, Anna"

Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes by Onken, Brian, Sedore, Christine A., Coleman‐Hulbert, Anna L., Hall, David, Johnson, Erik, Jones, Eleanor Grace, Banse, Stephen A., Huynh, Phu, Guo, Suzhen, Xue, Jian, Chen, Esteban, Harinath, Girish, Foulger, Anna C., Chao, Elizabeth A., Hope, June, Bhaumik, Dipa, Plummer, Todd, Inman, Delaney, Morshead, Mackenzie, Guo, Max, Lithgow, Gordon J., Phillips, Patrick C., Driscoll, Monica

“…Metformin, the most commonly prescribed anti‐diabetes medication, has multiple reported health benefits, including lowering the risks of cardiovascular disease…”
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The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging by Angeli, Suzanne, Foulger, Anna, Chamoli, Manish, Peiris, Tanuja Harshani, Gerencser, Akos, Shahmirzadi, Azar Asadi, Andersen, Julie, Lithgow, Gordon

“…Mitochondrial activity determines aging rate and the onset of chronic diseases. The mitochondrial permeability transition pore (mPTP) is a pathological pore in…”
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Potassium-chelating drug sodium polystyrene sulfonate enhances lysosomal function and suppresses proteotoxicity by Arputhasamy, Cyrene, Foulger, Anna C., Lucanic, Mark, Rane, Anand, Schmidt, Minna, Garrett, Theo, Broussalian, Michael, Battistoni, Elena, Brem, Rachel B., Lithgow, Gordon J., Chamoli, Manish, Andersen, Julie K.

“…  Lysosomes are crucial for degradation and recycling of damaged proteins and cellular components. Therapeutic strategies enhancing lysosomal function are a…”
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Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes by Banse, Stephen A., Sedore, Christine A., Johnson, Erik, Coleman-Hulbert, Anna L., Onken, Brian, Hall, David, Jackson, E. Grace, Huynh, Phu, Foulger, Anna C., Guo, Suzhen, Garrett, Theo, Xue, Jian, Inman, Delaney, Morshead, Mackenzie L., Plummer, W. Todd, Chen, Esteban, Bhaumik, Dipa, Chen, Michelle K., Harinath, Girish, Chamoli, Manish, Quinn, Rose P., Falkowski, Ron, Edgar, Daniel, Schmidt, Madeline O., Lucanic, Mark, Guo, Max, Driscoll, Monica, Lithgow, Gordon J., Phillips, Patrick C.

“…The Caenorhabditis Intervention Testing Program (CITP) is an NIH-funded research consortium of investigators who conduct analyses at three independent sites to…”
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Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions by Banse, Stephen A., Lucanic, Mark, Sedore, Christine A., Coleman-Hulbert, Anna L., Plummer, W. Todd, Chen, Esteban, Kish, Jason L., Hall, David, Onken, Brian, Presley, Michael P., Jones, E. Grace, Blue, Benjamin W., Garrett, Theo, Abbott, Mark, Xue, Jian, Guo, Suzhen, Johnson, Erik, Foulger, Anna C., Chamoli, Manish, Falkowski, Ron, Melentijevic, Ilija, Harinath, Girish, Huynh, Phu, Patel, Shobhna, Edgar, Daniel, Jarrett, Cody M., Guo, Max, Kapahi, Pankaj, Lithgow, Gordon J., Driscoll, Monica, Phillips, Patrick C.

“…The goal of the Caenorhabditis Intervention Testing Program is to identify robust and reproducible pro-longevity interventions that are efficacious across…”
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Amyloid β accelerates age-related proteome-wide protein insolubility by Anderton, Edward, Chamoli, Manish, Bhaumik, Dipa, King, Christina D., Xie, Xueshu, Foulger, Anna, Andersen, Julie K., Schilling, Birgit, Lithgow, Gordon J.

“…Loss of proteostasis is a highly conserved feature of aging across model organisms and results in the accumulation of insoluble protein aggregates. Protein…”
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A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan by Chamoli, Manish, Rane, Anand, Foulger, Anna, Chinta, Shankar J, Shahmirzadi, Azar Asadi, Kumsta, Caroline, Nambiar, Dhanya K, Hall, David, Holcom, Angelina, Angeli, Suzanne, Schmidt, Minna, Pitteri, Sharon, Hansen, Malene, Lithgow, Gordon J, Andersen, Julie K

“…Autophagy-lysosomal function is crucial for maintaining healthy lifespan and preventing age-related diseases. The transcription factor TFEB plays a key role in…”
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Caenorhabditis Intervention Testing Program: the herbicide diuron does not robustly extend lifespan in nematodes by Osman, Hadley C, Sedore, Christine A, Jackson, E Grace, Battistoni, Elena T, Hall, David, Foulger, Anna, Lucanic, Mark, Guo, Max, Driscoll, Monica, Phillips, Patrick, Lithgow, Gordon J

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An aco-2::gfp knock-in enables the monitoring of mitochondrial morphology throughout C. elegans lifespan by Begelman, David V, Woods, Georgia, Bhaumik, Dipa, Angeli, Suzanne, Foulger, Anna C, Lucanic, Mark, Lan, Jianfeng, Andersen, Julie K, Lithgow, Gordon J

“…We used CRISPR/Cas9 gene editing in in order to fluorescently tag endogenous aconitase-2 (ACO-2). ACO-2 is a mitochondrially localized protein, and the strain…”
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