Search Results - "Fouda, Genevieve G"
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The Impact of IgG transplacental transfer on early life immunity
Published in ImmunoHorizons (01-01-2018)“…Pediatric vaccines have significantly reduced infectious disease-related infant mortality, but as protective immunity often require several infant vaccine…”
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Understanding Early-Life Adaptive Immunity to Guide Interventions for Pediatric Health
Published in Frontiers in immunology (21-01-2021)“…Infants are capable of mounting adaptive immune responses, but their ability to develop long-lasting immunity is limited. Understanding the particularities of…”
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Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?
Published in PLoS pathogens (30-08-2018)Get full text
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Maternal Fc-mediated non-neutralizing antibody responses correlate with protection against congenital human cytomegalovirus infection
Published in The Journal of clinical investigation (15-08-2022)“…Human cytomegalovirus (HCMV) is the most common congenital infection and a leading cause of stillbirth, neurodevelopmental impairment, and pediatric hearing…”
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Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation
Published in PLoS pathogens (26-10-2020)“…Globally, 1.8 million children are living with HIV-1. While antiretroviral therapy (ART) has improved disease outcomes, it does not eliminate the latent HIV-1…”
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Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health
Published in Nature nanotechnology (01-04-2021)Get full text
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Characterization of the primary antibody response to Plasmodium falciparum antigens in infants living in a malaria-endemic area
Published in Malaria journal (19-11-2022)“…The primary antibody (Ab) response to Plasmodium falciparum is a critical step in developing immunity to malaria. Information on the initial Ab responses of…”
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Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models
Published in Journal of virology (15-05-2019)“…Studies in animal models are essential prerequisites for clinical trials of candidate HIV vaccines. Small animals, such as rabbits, are used to evaluate…”
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Tenascin-C is an innate broad-spectrum, HIV-1–neutralizing protein in breast milk
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2013)“…Achieving an AIDS-free generation will require elimination of postnatal transmission of HIV-1 while maintaining the nutritional and immunologic benefits of…”
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Harnessing early life immunity to develop a pediatric HIV vaccine that can protect through adolescence
Published in PLoS pathogens (01-11-2020)“…[...]elicitation of bNabs is a major goal for an efficacious HIV vaccine. An HIV vaccine administered at birth with successive boosting during infancy will…”
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HIV envelope antigen valency on peptide nanofibers modulates antibody magnitude and binding breadth
Published in Scientific reports (14-07-2021)“…A major challenge in developing an effective vaccine against HIV-1 is the genetic diversity of its viral envelope. Because of the broad range of sequences…”
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Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
Published in JCI insight (08-09-2021)“…As SARS-CoV-2 continues to spread globally, questions have emerged regarding the strength and durability of immune responses in specific populations. In this…”
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Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma
Published in PLoS pathogens (19-04-2018)“…Despite extensive genetic diversity of HIV-1 in chronic infection, a single or few maternal virus variants become the founders of an infant's infection. These…”
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Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure
Published in Frontiers in immunology (13-07-2022)“…Early initiation of antiretroviral therapy (ART) significantly improves clinical outcomes and reduces mortality of infants/children living with HIV. However,…”
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Cost‐effectiveness of broadly neutralizing antibody prophylaxis for HIV‐exposed infants in sub‐Saharan African settings
Published in Journal of the International AIDS Society (01-01-2023)“…Introduction Infant HIV prophylaxis with broadly neutralizing anti‐HIV antibodies (bNAbs) could provide long‐acting protection against vertical transmission…”
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Determinants of Tenascin-C and HIV-1 envelope binding and neutralization
Published in Mucosal immunology (01-07-2019)“…Interactions between innate antiviral factors at mucosal surfaces and HIV-1 virions contribute to the natural inefficiency of HIV-1 transmission and are a…”
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Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies
Published in Journal of Virology (01-11-2011)“…Author's Correction ( vol. 87 , p. 13936 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques
Published in Epidemics (01-09-2024)“…While the benefits of early antiretroviral therapy (ART) initiation in perinatally infected infants are well documented, early initiation is not always…”
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Mucosal Immunization of Lactating Female Rhesus Monkeys with a Transmitted/Founder HIV-1 Envelope Induces Strong Env-Specific IgA Antibody Responses in Breast Milk
Published in Journal of Virology (01-06-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Origin and Evolution of HIV-1 in Breast Milk Determined by Single-Genome Amplification and Sequencing
Published in Journal of Virology (01-03-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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