Search Results - "Fotia, Andrew B."

Regulation of Neuronal Voltage-gated Sodium Channels by the Ubiquitin-Protein Ligases Nedd4 and Nedd4-2 by Fotia, Andrew B, Ekberg, Jenny, Adams, David J, Cook, David I, Poronnik, Philip, Kumar, Sharad

“…Nedd4 and Nedd4-2 are ubiquitin-protein ligases known to regulate a number of membrane proteins including receptors and ion transporters. Regulation of the…”
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The Kinase Grk2 Regulates Nedd4/Nedd4-2-Dependent Control of Epithelial Na+Channels by Dinudom, Anuwat, Fotia, Andrew B., Lefkowitz, Robert J., Young, John A., Kumar, Sharad, Cook, David I., Giebisch, Gerhard

“…Epithelia Na+channels mediate the transport of Na across epithelia in the kidney, gut, and lungs and are required for blood pressure regulation. They are…”
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The role of individual Nedd4–2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels by Fotia, Andrew B., Dinudom, Anuwat, Shearwin, Keith E., Koch, Jan‐Peter, Korbmacher, Christoph, Cook, David I., Kumar, Sharad

“…ABSTRACT The amiloride‐sensitive epithelial sodium channel (ENaC) is essential for fluid and electrolyte homeostasis. ENaC consists of α, β, and γ subunits,…”
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EGF receptor-independent action of TGF-α protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation by Ding, Wei, Li, Cunxi, Hu, Tianhui, Graves-Deal, Ramona, Fotia, Andrew B, Weissman, Allan M, Coffey, Robert J

“…Naked family members (Drosophila Naked Cuticle and mammalian Naked1 and Naked2) have been identified as inducible antagonists of canonical Wnt signaling. We…”
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Regulation of the Epithelial Sodium Channel by N4WBP5A, a Novel Nedd4/Nedd4-2-interacting Protein by Konstas, Angelos-Aristeidis, Shearwin-Whyatt, Linda M., Fotia, Andrew B., Degger, Brian, Riccardi, Daniela, Cook, David I., Korbmacher, Christoph, Kumar, Sharad

“…The amiloride-sensitive epithelial sodium channel (ENaC) plays a critical role in fluid and electrolyte homeostasis and consists of α, β, and γ subunits. The…”
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Stimulation of the epithelial sodium channel (ENaC) by the serum- and glucocorticoid-inducible kinase (Sgk) involves the PY motifs of the channel but is independent of sodium feedback inhibition by Rauh, Robert, Dinudom, Anuwat, Fotia, Andrew B, Paulides, Marios, Kumar, Sharad, Korbmacher, Christoph, Cook, David I

“…The epithelial sodium channel (ENaC) is the major mediator of sodium transport across the apical membranes of the distal nephron, the distal colon, the…”
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The ubiquitin-protein ligases Nedd4 and Nedd4-2 show similar ubiquitin-conjugating enzyme specificities by Fotia, Andrew B., Cook, David I., Kumar, Sharad

“…Nedd4 and Nedd4-2 are closely related HECT-type ubiquitin-protein ligases (E3) implicated in the regulation of a number of proteins and pathways. Given the…”
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EGF receptor-independent action of TGF-[alpha] protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation by Ding, Wei, Li, Cunxi, Hu, Tianhui, Graves-Deal, Ramona, Fotia, Andrew B, Weissman, Allan M, Coffey, Robert J

“…Naked family members (Drosophila Naked Cuticle and mammalian Naked1 and Naked2) have been identified as inducible antagonists of canonical Wnt signaling. We…”
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