Search Results - "Foster Olive, M"
-
1
Glutamatergic substrates of drug addiction and alcoholism
Published in Biochemical pharmacology (2008)“…The past two decades have witnessed a dramatic accumulation of evidence indicating that the excitatory amino acid glutamate plays an important role in drug…”
Get full text
Journal Article -
2
Cognitive deficits and neurotoxicity induced by synthetic cathinones: is there a role for neuroinflammation?
Published in Psychopharmacology (01-03-2019)“…Rationale The number of synthetic derivatives of cathinone, the primary psychoactive alkaloid found in Catha edulis (khat), has risen exponentially in the past…”
Get full text
Journal Article -
3
AMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2019)“…Cue-induced drug craving progressively intensifies after withdrawal from self-administration of cocaine, methamphetamine, and other drugs of abuse, a…”
Get full text
Journal Article -
4
Nuclear factor kappa B signaling within the rat nucleus accumbens core sex-dependently regulates cue-induced cocaine seeking and matrix metalloproteinase-9 expression
Published in Brain, behavior, and immunity (01-05-2022)“…•Viral-mediated inhibition of nucleus accumbens core (NAc core) NF-κB signaling suppresses cue-motivated cocaine seeking in male, but not female,…”
Get full text
Journal Article -
5
Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction
Published in European journal of pharmacology (10-08-2010)“…Glutamate plays a pivotal role in regulating drug self-administration and drug-seeking behavior, and the past decade has witnessed a substantial surge of…”
Get full text
Journal Article -
6
Glutamatergic medications for the treatment of drug and behavioral addictions
Published in Pharmacology, biochemistry and behavior (01-02-2012)“…Historically, most pharmacological approaches to the treatment of addictive disorders have utilized either substitution-based methods (i.e., nicotine…”
Get full text
Journal Article -
7
The dynamics of heroin and illicit opioid use disorder, casual use, treatment, and recovery: A mathematical modeling analysis
Published in Mathematical biosciences and engineering : MBE (01-02-2024)“…A leading crisis in the United States is the opioid use disorder (OUD) epidemic. Opioid overdose deaths have been increasing, with over 100,000 deaths due to…”
Get full text
Journal Article -
8
Effects of heroin on rat prosocial behavior
Published in Addiction biology (01-07-2019)“…Opioid use disorders are characterized in part by impairments in social functioning. Previous research indicates that laboratory rats, which are frequently…”
Get full text
Journal Article -
9
A line before liquor: a novel model of cocaine and alcohol co-abuse reveals changes in glutamate homeostasis
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2020)Get full text
Journal Article -
10
Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving
Published in Nature neuroscience (2014)“…Accumulation of calcium-permeable AMPA receptors at nucleus accumbens synapses underlies the intensified cue-induced cocaine craving observed after prolonged…”
Get full text
Journal Article -
11
mGluR5 Positive Allosteric Modulators Facilitate both Hippocampal LTP and LTD and Enhance Spatial Learning
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2009)“…Highly selective positive allosteric modulators (PAMs) of metabotropic glutamate receptor subtype 5 (mGluR5) have emerged as a potential approach to treat…”
Get full text
Journal Article -
12
Neuroimmune Mechanisms as Novel Treatment Targets for Substance Use Disorders and Associated Comorbidities
Published in Frontiers in neuroscience (15-04-2021)“…Recent studies examining the neurobiology of substance abuse have revealed a significant role of neuroimmune signaling as a mechanism through which drugs of…”
Get full text
Journal Article -
13
Loss of Object Recognition Memory Produced by Extended Access to Methamphetamine Self-Administration is Reversed by Positive Allosteric Modulation of Metabotropic Glutamate Receptor 5
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2011)“…Chronic methamphetamine (meth) abuse can lead to persisting cognitive deficits. Here, we utilized a long-access meth self-administration (SA) protocol to…”
Get full text
Journal Article -
14
Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex
Published in The Journal of neuroscience (28-05-2014)“…Addiction is a chronic relapsing disorder in which relapse is often initiated by exposure to drug-related cues. The present study examined the effects of…”
Get full text
Journal Article -
15
Calcium‐permeable AMPA receptors and silent synapses in cocaine‐conditioned place preference
Published in The EMBO journal (15-02-2017)“…Exposure to cocaine generates silent synapses in the nucleus accumbens (NAc), whose eventual unsilencing/maturation by recruitment of calcium‐permeable…”
Get full text
Journal Article -
16
Editorial: When the prefrontal cortex network goes wrong: the neuroinflammatory impact on behavioral disorders
Published in Frontiers in behavioral neuroscience (08-01-2024)“…[...]Shanazz et al. explore susceptibility and resiliency to PTSD in rats, finding that susceptibility to a PTSD-like phenotype is positively correlated with…”
Get full text
Journal Article -
17
Chronic stress disrupts fear extinction and enhances amygdala and hippocampal Fos expression in an animal model of post-traumatic stress disorder
Published in Neurobiology of learning and memory (01-07-2014)“…•Chronic stress increases contextual fear during extinction.•Chronic stress-enhanced fear memories generalize to a novel context.•Chronic stress enhances…”
Get full text
Journal Article -
18
Restoration of prosocial behavior in rats after heroin self-administration via chemogenetic activation of the anterior insular cortex
Published in Social neuroscience (03-07-2020)“…The anterior insular cortex (AIC) mediates various social, emotional, and interoceptive components of addiction. We recently demonstrated a disruption of…”
Get full text
Journal Article -
19
Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density
Published in PloS one (12-09-2016)“…The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators of neuronal structure and function. Although these receptors share…”
Get full text
Journal Article -
20
Ethanol has concentration-dependent effects on hypothalamic POMC neuronal excitability
Published in Alcohol (Fayetteville, N.Y.) (01-08-2020)“…Alcohol abuse is a worldwide public health concern, yet the precise molecular targets of alcohol in the brain are still not fully understood. Alcohol may…”
Get full text
Journal Article