Search Results - "Foster, P L"

MECHANISMS OF STATIONARY PHASE MUTATION: A Decade of Adaptive Mutation by Foster, P. L

“…A decade of research on adaptive mutation has revealed a plethora of mutagenic mechanisms that may be important in evolution. The DNA synthesis associated with…”
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Adaptive Reversion of a Frameshift Mutation in Escherichia coli by Cairns, J, Foster, P. L

“…Mutation rates are generally thought not to be influenced by selective forces. This doctrine rests on the results of certain classical studies of the mutations…”
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Nonadaptive mutations occur on the F' episome during adaptive mutation conditions in Escherichia coli by Foster, P L

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Two Enzymes, Both of Which Process Recombination Intermediates, Have Opposite Effects on Adaptive Mutation in Escherichia coli by Foster, P. L, Trimarchi, J. M, Maurer, R. A

“…Reversion of a lac- frameshift allele carried on an F' episome in Escherichia coli occurs at a high rate when the cells are placed under lactose selection…”
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Population Dynamics of a Lac(-) Strain of Escherichia coli During Selection for Lactose Utilization by Foster, P. L

“…During selection for lactose utilization, Lac+ revertants of FC40, a Lac- strain of Escherichia coli, appear at a high rate. Yet, no Lac+ revertants appear in…”
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Adaptive mutation : the uses of adversity by FOSTER, P. L

“…When populations of microorganisms are subjected to certain nonlethal selections, useful mutants arise among the nongrowing cells whereas useless mutants do…”
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Mechanisms of Directed Mutation by Foster, P. L, Cairns, J

“…Spontaneous mutants arise among nondividing populations of Escherichia coli in apparent response to selective conditions. In this report we investigate several…”
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Adaptive mutation in Escherichia coli by Foster, P L

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Adaptive Reversion of a Frameshift Mutation in Escherichia coli by Simple Base Deletions in Homopolymeric Runs by Foster, Patricia L., Trimarchi, Jeffrey M.

“…Spontaneous mutations are thought to occur primarily in growing cells. However, spontaneous mutations also arise in nutritionally deprived cells, and in some…”
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Stress responses and genetic variation in bacteria by Foster, Patricia L

“…Under stressful conditions mechanisms that increase genetic variation can bestow a selective advantage. Bacteria have several stress responses that provide…”
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Adaptive Reversion of an Episomal Frameshift Mutation in Escherichia coli Requires Conjugal Functions but not Actual Conjugation by Foster, Patricia L., Trimarchi, Jeffrey M.

“…Adaptive reversion of a lac-frameshift mutation in Escherichia coli appears to be due to DNA polymerase errors, implying that DNA is being synthesized although…”
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Are adaptive mutations due to a decline in mismatch repair? The evidence is lacking by FOSTER, P. L

“…The levels of proteins required for methyl-directed mismatch repair appear to decline in stationary-phase and nutritionally-deprived cells of Escherichia coli…”
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Involvement of Escherichia coli DNA polymerase II in response to oxidative damage and adaptive mutation by Escarceller, M, Hicks, J, Gudmundsson, G, Trump, G, Touati, D, Lovett, S, Foster, P L, McEntee, K, Goodman, M F

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Directed mutation : between unicorns and goats by FOSTER, P. L

“…Directed mutation refers to the way bacteria seem to be able to produce the most appropriate mutations in a given environment. The latest research on directed…”
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The Coordinated Functions of the E. coli MutS and MutL Proteins in Mismatch Repair by Acharya, Samir, Foster, Patricia L., Brooks, Peter, Fishel, Richard

“…The Escherichia coli MutS and MutL proteins have been conserved throughout evolution, although their combined functions in mismatch repair (MMR) are poorly…”
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Proofreading-Defective DNA Polymerase II Increases Adaptive Mutation in Escherichia coli by Foster, Patricia L., Gudmundsson, Gudmundur, Trimarchi, Jeffrey M., Cai, Hong, Goodman, Myron F.

“…The role of Escherichia coli DNA polymerase (Pol) II in producing or avoiding mutations was investigated by replacing the chromosomal Pol II gene (polB+) by a…”
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Error‐prone DNA polymerase IV is controlled by the stress‐response sigma factor, RpoS, in Escherichia coli by Layton, Jill C., Foster, Patricia L.

“…Summary An insertion in rpoS, which encodes the general stress response sigma factor σ38, was isolated as an antimutator for ‘stationary‐phase’ or ‘adaptive’…”
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Conjugation is not required for adaptive reversion of an episomal frameshift mutation in Escherichia coli by Foster, P L, Trimarchi, J M

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Adaptive mutation: implications for evolution by Foster, Patricia L.

“…Adaptive mutation is defined as a process that, during nonlethal selections, produces mutations that relieve the selective pressure whether or not other,…”
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Determining Mutation Rates in Bacterial Populations by Rosche, William A., Foster, Patricia L.

“…When properly determined, spontaneous mutation rates are a more accurate and biologically meaningful reflection of underlying mutagenic mechanisms than are…”
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