Search Results - "Foster, Jeremy M"

Defining the filarial N-glycoproteome by glycosite mapping in the human parasitic nematode Brugia malayi by Mersha, Fana B., McClung, Colleen M., Chen, Minyong, Ruse, Cristian I., Foster, Jeremy M.

“…N-linked glycosylation is a critical post translational modification of eukaryotic proteins. N-linked glycans are present on surface and secreted filarial…”
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Dual RNA-seq in filarial nematodes and Wolbachia endosymbionts using RNase H based ribosomal RNA depletion by Cantin, Lindsey J, Gregory, Vanessa, Blum, Laura N, Foster, Jeremy M

“…Lymphatic filariasis is caused by parasitic nematodes and is a leading cause of disability worldwide. Many filarial worms contain the bacterium as an obligate…”
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Improved metagenome assemblies through selective enrichment of bacterial genomic DNA from eukaryotic host genomic DNA using ATAC-seq by Cantin, Lindsey J, Dunning Hotopp, Julie C, Foster, Jeremy M

“…Genomics can be used to study the complex relationships between hosts and their microbiota. Many bacteria cannot be cultured in the laboratory, making it…”
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Sex chromosome evolution in parasitic nematodes of humans by Foster, Jeremy M., Grote, Alexandra, Mattick, John, Tracey, Alan, Tsai, Yu-Chih, Chung, Matthew, Cotton, James A., Clark, Tyson A., Geber, Adam, Holroyd, Nancy, Korlach, Jonas, Li, Yichao, Libro, Silvia, Lustigman, Sara, Michalski, Michelle L., Paulini, Michael, Rogers, Matthew B., Teigen, Laura, Twaddle, Alan, Welch, Lonnie, Berriman, Matthew, Dunning Hotopp, Julie C., Ghedin, Elodie

“…Sex determination mechanisms often differ even between related species yet the evolution of sex chromosomes remains poorly understood in all but a few model…”
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Transient Accumulation of 5-Carboxylcytosine Indicates Involvement of Active Demethylation in Lineage Specification of Neural Stem Cells by Wheldon, Lee M., Abakir, Abdulkadir, Ferjentsik, Zoltan, Dudnakova, Tatiana, Strohbuecker, Stephanie, Christie, Denise, Dai, Nan, Guan, Shengxi, Foster, Jeremy M., Corrêa, Ivan R., Loose, Matthew, Dixon, James E., Sottile, Virginie, Johnson, Andrew D., Ruzov, Alexey

“…5-Methylcytosine (5mC) is an epigenetic modification involved in regulation of gene activity during differentiation. Tet dioxygenases oxidize 5mC to…”
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Widespread Lateral Gene Transfer from Intracellular Bacteria to Multicellular Eukaryotes by Hotopp, Julie C. Dunning, Clark, Michael E, Oliveira, Deodoro C.S.G, Foster, Jeremy M, Fischer, Peter, Torres, Mónica C. Muñoz, Giebel, Jonathan D, Kumar, Nikhil, Ishmael, Nadeeza, Wang, Shiliang, Ingram, Jessica, Nene, Rahul V, Shepard, Jessica, Tomkins, Jeffrey, Richards, Stephen, Spiro, David J, Ghedin, Elodie, Slatko, Barton E, Tettelin, Hervé, Werren, John H

“…Although common among bacteria, lateral gene transfer--the movement of genes between distantly related organisms--is thought to occur only rarely between…”
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The Wolbachia endosymbiont as an anti-filarial nematode target by Slatko, Barton E., Taylor, Mark J., Foster, Jeremy M.

“…Human disease caused by parasitic filarial nematodes is a major cause of global morbidity. The parasites are transmitted by arthropod intermediate hosts and…”
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Co-evolution between an endosymbiont and its nematode host: Wolbachia asymmetric posterior localization and AP polarity establishment by Landmann, Frederic, Foster, Jeremy M, Michalski, Michelle L, Slatko, Barton E, Sullivan, William

“…While bacterial symbionts influence a variety of host cellular responses throughout development, there are no documented instances in which symbionts influence…”
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Alteration of rhesus macaque serum N-glycome during infection with the human parasitic filarial nematode Brugia malayi by Petralia, Laudine M. C., Santha, Esrath, Behrens, Anna-Janina, Nguyen, D. Linh, Ganatra, Mehul B., Taron, Christopher H., Khatri, Vishal, Kalyanasundaram, Ramaswamy, van Diepen, Angela, Hokke, Cornelis H., Foster, Jeremy M.

“…Serum N-glycan profiling studies during the past decades have shown robust associations between N-glycan changes and various biological conditions, including…”
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Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts by Chevignon, Germain, Foray, Vincent, Pérez-Jiménez, Mercedes Maria, Libro, Silvia, Chung, Matthew, Foster, Jeremy M, Landmann, Frédéric

“…Brugia malayi is a human filarial nematode responsible for elephantiasis, a debilitating condition that is part of a broader spectrum of diseases called…”
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Population genomic evidence that human and animal infections in Africa come from the same populations of Dracunculus medinensis by Durrant, Caroline, Thiele, Elizabeth A, Holroyd, Nancy, Doyle, Stephen R, Sallé, Guillaume, Tracey, Alan, Sankaranarayanan, Geetha, Lotkowska, Magda E, Bennett, Hayley M, Huckvale, Thomas, Abdellah, Zahra, Tchindebet, Ouakou, Wossen, Mesfin, Logora, Makoy Samuel Yibi, Coulibaly, Cheick Oumar, Weiss, Adam, Schulte-Hostedde, Albrecht I, Foster, Jeremy M, Cleveland, Christopher A, Yabsley, Michael J, Ruiz-Tiben, Ernesto, Berriman, Matthew, Eberhard, Mark L, Cotton, James A

“…Guinea worm-Dracunculus medinensis-was historically one of the major parasites of humans and has been known since antiquity. Now, Guinea worm is on the brink…”
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Asymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissues by Landmann, Frédéric, Foster, Jeremy M, Slatko, Barton, Sullivan, William

“…Wolbachia are required for filarial nematode survival and fertility and contribute to the immune responses associated with human filarial diseases. Here we…”
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Unraveling cross-reactivity of anti-glycan IgG responses in filarial nematode infections by Petralia, Laudine M C, van Diepen, Angela, Nguyen, Dieu-Linh, Lokker, Lena A, Sartono, Erliyani, Bennuru, Sasisekhar, Nutman, Thomas B, Pfarr, Kenneth, Hoerauf, Achim, Wanji, Samuel, Foster, Jeremy M, Hokke, Cornelis H

“…Parasitic nematodes responsible for filarial diseases cause chronic disablement in humans worldwide. Elimination programs have substantially reduced the rate…”
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Targeted Enrichment and Sequencing of Recent Endosymbiont-Host Lateral Gene Transfers by Dunning Hotopp, Julie C., Slatko, Barton E., Foster, Jeremy M.

“…Lateral gene transfer (LGT) from microbial symbionts to invertebrate animals is described at an increasing rate, particularly between Wolbachia endosymbionts…”
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Computational and experimental analysis of the glycophosphatidylinositol-anchored proteome of the human parasitic nematode Brugia malayi by Mersha, Fana B, Cortes, Leslie K, Luck, Ashley N, McClung, Colleen M, Ruse, Cristian I, Taron, Christopher H, Foster, Jeremy M

“…Further characterization of essential systems in the parasitic filarial nematode Brugia malayi is needed to better understand its biology, its interaction with…”
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Removing the needle from the haystack: Enrichment of Wolbachia endosymbiont transcripts from host nematode RNA by Cappable-seq by Luck, Ashley N, Slatko, Barton E, Foster, Jeremy M

“…Efficient transcriptomic sequencing of microbial mRNA derived from host-microbe associations is often compromised by the much lower relative abundance of…”
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Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi by Holman, Alexander G, Davis, Paul J, Foster, Jeremy M, Carlow, Clotilde K S, Kumar, Sanjay

“…Wolbachia (wBm) is an obligate endosymbiotic bacterium of Brugia malayi, a parasitic filarial nematode of humans and one of the causative agents of lymphatic…”
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Mining predicted essential genes of Brugia malayi for nematode drug targets by Kumar, Sanjay, Chaudhary, Kshitiz, Foster, Jeremy M, Novelli, Jacopo F, Zhang, Yinhua, Wang, Shiliang, Spiro, David, Ghedin, Elodie, Carlow, Clotilde K S

“…We report results from the first genome-wide application of a rational drug target selection methodology to a metazoan pathogen genome, the completed draft…”
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X-treme loss of sequence diversity linked to neo-X chromosomes in filarial nematodes by Mattick, John, Libro, Silvia, Bromley, Robin, Chaicumpa, Wanpen, Chung, Matthew, Cook, Darren, Khan, Mohammad Behram, Kumar, Nikhil, Lau, Yee-Ling, Misra-Bhattacharya, Shailja, Rao, Ramakrishna, Sadzewicz, Lisa, Saeung, Atiporn, Shahab, Mohd, Sparklin, Benjamin C, Steven, Andrew, Turner, Joseph D, Tallon, Luke J, Taylor, Mark J, Moorhead, Andrew R, Michalski, Michelle, Foster, Jeremy M, Dunning Hotopp, Julie C

“…The sequence diversity of natural and laboratory populations of Brugia pahangi and Brugia malayi was assessed with Illumina resequencing followed by mapping in…”
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Nematode-Bacterium Symbioses—Cooperation and Conflict Revealed in the “Omics” Age by MURFIN, KRISTEN E., DILLMAN, ADLER R., FOSTER, JEREMY M., BULGHERESI, SILVIA, SLATKO, BARTON E., STERNBERG, PAUL W., GOODRICH-BLAIR, HEIDI

“…Nematodes are ubiquitous organisms that have a significant global impact on ecosystems, economies, agriculture, and human health. The applied importance of…”
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