Search Results - "Foster, James S"

Preclinical evaluation of Tc-99m p5+14 peptide for SPECT detection of cardiac amyloidosis by Kennel, Stephen J, Jackson, Joseph W, Stuckey, Alan, Richey, Tina, Foster, James S, Wall, Jonathan S

“…Amyloid deposition is a cause of restrictive cardiomyopathy. Patients who present with cardiac disease can be evaluated for transthyretin (TTR)-associated…”
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Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes by McWilliams-Koeppen, Helen P, Foster, James S, Hackenbrack, Nicole, Ramirez-Alvarado, Marina, Donohoe, Dallas, Williams, Angela, Macy, Sallie, Wooliver, Craig, Wortham, Dale, Morrell-Falvey, Jennifer, Foster, Carmen M, Kennel, Stephen J, Wall, Jonathan S

“…Light chain (AL) amyloidosis is the most common form of systemic amyloid disease, and cardiomyopathy is a dire consequence, resulting in an extremely poor…”
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Development and characterization of a prototypic pan-amyloid clearing agent – a novel murine peptide-immunoglobulin fusion by Foster, James S., Balachandran, Manasi, Hancock, Trevor J., Martin, Emily B., Macy, Sallie, Wooliver, Craig, Richey, Tina, Stuckey, Alan, Williams, Angela D., Jackson, Joseph W., Kennel, Stephen J., Wall, Jonathan S.

“…Introduction Systemic amyloidosis is a progressive disorder characterized by the extracellular deposition of amyloid fibrils and accessory proteins in visceral…”
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Collagen inhibits phagocytosis of amyloid in vitro and in vivo and may act as a 'don't eat me' signal by Jackson, Joseph W., Foster, James S., Martin, Emily B., Macy, Sallie, Wooliver, Craig, Balachandran, Manasi, Richey, Tina, Heidel, R. Eric, Williams, Angela D., Kennel, Stephen J., Wall, Jonathan S.

“…Systemic amyloidosis refers to a group of protein misfolding disorders characterized by the extracellular deposition of amyloid fibrils in organs and tissues…”
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Macrophage-Mediated Phagocytosis and Dissolution of Amyloid-Like Fibrils in Mice, Monitored by Optical Imaging by Richey, Tina, Foster, James S., Williams, Angela D., Williams, Anna B., Stroh, Alexa, Macy, Sallie, Wooliver, Craig, Heidel, R. Eric, Varanasi, Siva K., Ergen, Elizabeth N., Trent, Dianne J., Kania, Stephen A., Kennel, Stephen J., Martin, Emily B., Wall, Jonathan S.

“…Light chain–associated amyloidosis is characterized by the extracellular deposition of amyloid fibrils in abdominothoracic organs, skin, soft tissue, and…”
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Clinical Confirmation of Pan-Amyloid Reactivity of Radioiodinated Peptide 124I-p5+14 (AT-01) in Patients with Diverse Types of Systemic Amyloidosis Demonstrated by PET/CT Imaging by Martin, Emily B., Stuckey, Alan, Powell, Dustin, Lands, Ronald, Whittle, Bryan, Wooliver, Craig, Macy, Sallie, Foster, James S., Guthrie, Spencer, Kennel, Stephen J., Wall, Jonathan S.

“…There are at least 20 distinct types of systemic amyloidosis, all of which result in the organ-compromising accumulation of extracellular amyloid deposits…”
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Novel heparan sulfate-binding peptides for blocking herpesvirus entry by Dogra, Pranay, Martin, Emily B, Williams, Angela, Richardson, Raphael L, Foster, James S, Hackenback, Nicole, Kennel, Stephen J, Sparer, Tim E, Wall, Jonathan S

“…Human cytomegalovirus (HCMV) infection can lead to congenital hearing loss and mental retardation. Upon immune suppression, reactivation of latent HCMV or…”
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Evaluation of the effect of D-amino acid incorporation into amyloid-reactive peptides by Martin, Emily B, Williams, Angela, Richey, Tina, Wooliver, Craig, Stuckey, Alan, Foster, James S, Kennel, Stephen J, Wall, Jonathan S

“…Systemic amyloidoses comprise diseases characterized by the deposition of proteinaceous material known as amyloid. Currently, without performing multiple…”
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Preclinical Validation of the Heparin-Reactive Peptide p5+14 as a Molecular Imaging Agent for Visceral Amyloidosis by Wall, Jonathan S, Martin, Emily B, Richey, Tina, Stuckey, Alan C, Macy, Sallie, Wooliver, Craig, Williams, Angela, Foster, James S, McWilliams-Koeppen, Penney, Uberbacher, Ed, Cheng, Xiaolin, Kennel, Stephen J

“…Amyloid is a complex pathologic matrix comprised principally of paracrystalline protein fibrils and heparan sulfate proteoglycans. Systemic amyloid diseases…”
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A Peptide-Fc Opsonin with Pan-Amyloid Reactivity by Foster, James S, Williams, Angela D, Macy, Sallie, Richey, Tina, Stuckey, Alan, Wooliver, Daniel Craig, Koul-Tiwari, Richa, Martin, Emily B, Kennel, Stephen J, Wall, Jonathan S

“…There is a continuing need for therapeutic interventions for patients with the protein misfolding disorders that result in systemic amyloidosis. Recently,…”
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Expression of odontogenic ameloblast-associated protein (ODAM) in dental and other epithelial neoplasms by Kestler, Daniel P, Foster, James S, Macy, Sallie D, Murphy, Charles L, Weiss, Deborah T, Solomon, Alan

“…We previously have communicated our discovery that the amyloid associated with calcifying epithelial odontogenic tumors is composed of N-terminal fragments of…”
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Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling by Foster, James S, Fish, Lindsay M, Phipps, Jonathan E, Bruker, Charles T, Lewis, James M, Bell, John L, Solomon, Alan, Kestler, Daniel P

“…The Odontogenic Ameloblast-associated Protein (ODAM) is expressed in a wide range of normal epithelial, and neoplastic tissues, and we have posited that ODAM…”
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Odontogenic ameloblast-associated protein nature of the amyloid found in calcifying epithelial odontogenic tumors and unerupted tooth follicles by Murphy, Charles L., Kestler, Daniel P., Foster, James S., Wang, Shuching, Macy, Sallie D., Kennel, Stephen J., Carlson, Eric R., Hudson, John, Weiss, Deborah T., Solomon, Alan

“…We have previously reported that the amyloid found in three patients with calcifying epithelial odontogenic tumors (CEOT) was composed of N-terminal fragments…”
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Cardiac Amyloid Detection by PET/CT Imaging of Iodine ( 124 I) Evuzamitide ( 124 I-p5+14): A Phase 1/2 Study by Wall, Jonathan S, Martin, Emily B, Lands, Ronald, Ramchandren, Radhakrishnan, Stuckey, Alan, Heidel, R Eric, Whittle, Bryan, Powell, Dustin, Richey, Tina, Williams, Angela D, Foster, James S, Guthrie, Spencer, Kennel, Stephen J

“…The noninvasive detection of cardiac amyloid, as well as deposits in other vital organs, is critical for early diagnosis and quantitative disease monitoring…”
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Odontogenic ameloblast associated protein as a novel biomarker for human breast cancer by Siddiqui, Sabina, Bruker, C Todd, Kestler, Daniel P, Foster, James S, Gray, Keith D, Solomon, Alan, Bell, John L

“…Odontogenic Ameloblast Associated Protein (ODAM) is a protein isolated in ameloblasts during odontogenesis. ODAM expression was identified in breast cancer,…”
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Placental expression of estrogen receptor beta and its hormone binding variant--comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells by Bukovsky, Antonin, Caudle, Michael R, Cekanova, Maria, Fernando, Romaine I, Wimalasena, Jay, Foster, James S, Henley, Donald C, Elder, Robert F

“…During human pregnancy, the production of 17-beta-estradiol (E2) rises steadily to eighty fold at term, and placenta has been found to specifically bind…”
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Expression and localization of estrogen receptor-alpha protein in normal and abnormal term placentae and stimulation of trophoblast differentiation by estradiol by Bukovsky, Antonin, Cekanova, Maria, Caudle, Michael R, Wimalasena, Jay, Foster, James S, Henley, Donald C, Elder, Robert F

“…Estrogens play an important role in the regulation of placental function, and 17-beta-estradiol (E2) production rises eighty fold during human pregnancy…”
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Neutrophils enhance the clearance of systemic amyloid deposits in a murine amyloidoma model by Hancock, Trevor J., Vlasyuk, Marina, Foster, James S., Macy, Sallie, Wooliver, Daniel C., Balachandran, Manasi, Williams, Angela D., Martin, Emily B., Kennel, Stephen J., Heidel, Eric R., Wall, Jonathan S., Jackson, Joseph W.

“…Introduction Amyloid-specific antibodies have been shown to opsonize and enhance amyloid clearance in systemic amyloidosis mouse models. However, the…”
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ODAM Expression Inhibits Human Breast Cancer Tumorigenesis by Kestler, Daniel P., Foster, James S., Bruker, Charles T., Prenshaw, John W., Kennel, Stephen J., Wall, Jonathan S., Weiss, Deborah T., Solomon, Alan

“…We have posited that Odontogenic Ameloblast Associated Protein (ODAM) serves as a novel prognostic biomarker in breast cancer and now have investigated its…”
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Estrogen Receptor β Inhibits 17β-Estradiol-Stimulated Proliferation of the Breast Cancer Cell Line T47D by Ström, Anders, Hartman, Johan, Foster, James S., Kietz, Silke, Wimalasena, Jay, Gustafsson, Jan-Åke

“…Estrogen receptor (ER) β counteracts the activity of ERα in many systems. In agreement with this, we show in this study that induced expression of ERβ in the…”
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