Search Results - "Foster, Christine E."

Crystal Structure of the Human Natural Killer (NK) Cell Activating Receptor NKp46 Reveals Structural Relationship to Other Leukocyte Receptor Complex Immunoreceptors by Foster, Christine E., Colonna, Marco, Sun, Peter D.

“…Natural cytotoxicity receptors (NCR) mediate lysis of a variety of tumor and virus-infected cells by natural killer (NK) cells. Upon engagement, NCR trigger…”
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MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis by Cho, Min-Guk, Kumar, Rashmi J., Lin, Chien-Chu, Boyer, Joshua A., Shahir, Jamshaid A., Fagan-Solis, Katerina, Simpson, Dennis A., Fan, Cheng, Foster, Christine E., Goddard, Anna M., Lerner, Lynn M., Ellington, Simon W., Wang, Qinhong, Wang, Ying, Ho, Alice Y., Liu, Pengda, Perou, Charles M., Zhang, Qi, McGinty, Robert K., Purvis, Jeremy E., Gupta, Gaorav P.

“…Oncogene-induced replication stress generates endogenous DNA damage that activates cGAS–STING-mediated signalling and tumour suppression 1 – 3 . However, the…”
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Midwives' attitudes towards giving weight-related advice to obese pregnant women by Foster, Christine E, Hirst, Janet

“…It is estimated that 1 in 5 pregnant women are obese, this poses a significant risk to maternal, fetal and newborn mortality and morbidity and as such,…”
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New Superfamily Members Identified for Schiff-Base Enzymes Based on Verification of Catalytically Essential Residues by Choi, Kyung H, Lai, Vicky, Foster, Christine E, Morris, Aaron J, Tolan, Dean R, Allen, Karen N

“…Enzymes that utilize a Schiff-base intermediate formed with their substrates and that share the same α/β barrel fold comprise a mechanistically diverse…”
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Crystal Structure of Human Quinone Reductase Type 2, a Metalloflavoprotein by Foster, Christine E, Bianchet, Mario A, Talalay, Paul, Zhao, Qinjian, Amzel, L. Mario

“…In mammals, two separate but homologous cytosolic quinone reductases have been identified:  NAD(P)H:quinone oxidoreductase type 1 (QR1) (EC 1.6.99.2) and…”
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Structures of mammalian cytosolic quinone reductases by Foster, Christine E, Bianchet, Mario A, Talalay, Paul, Faig, Margarita, Amzel, L.Mario

“…The metabolism of quinone compounds presents one source of oxidative stress in mammals, as many pathways proceed by mechanisms that generate reactive oxygen…”
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Overview of protein structural and functional folds by Sun, Peter D, Foster, Christine E, Boyington, Jeffrey C

“…This overview provides an illustrated, comprehensive survey of some commonly observed protein-fold families and structural motifs, chosen for their functional…”
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Abstract A012: Mre11 mediates cGAS activation and tumor suppression through ZBP1-dependent necroptosis in breast cancer by Jo, Minguk, Kumar, Rashmi J., Lin, Chien-Chu, Boyer, Joshua A., Shahir, Jamshaid A., Fagan-Solis, Katerina, Simpson, Dennis A., Fan, Cheng, Foster, Christine E., Goddard, Anna M., Lerner, Lynn M., Ellington, Simon W., Wang, Qinhong, Wang, Ying, Ho, Alice Y., Liu, Pengda, Perou, Charles M., Zhang, Qi, McGinty, Robert K., Purvis, Jeremy E., Gupta, Gaorav P.

“…Oncogene-induced replication stress leads to endogenous DNA damage, activating the cGAS/STING signaling pathway, a critical player in tumor suppression. The…”
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