Search Results - "Foster, Christine E"
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Crystal Structure of the Human Natural Killer (NK) Cell Activating Receptor NKp46 Reveals Structural Relationship to Other Leukocyte Receptor Complex Immunoreceptors
Published in The Journal of biological chemistry (14-11-2003)“…Natural cytotoxicity receptors (NCR) mediate lysis of a variety of tumor and virus-infected cells by natural killer (NK) cells. Upon engagement, NCR trigger…”
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2
MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis
Published in Nature (London) (18-01-2024)“…Oncogene-induced replication stress generates endogenous DNA damage that activates cGAS–STING-mediated signalling and tumour suppression 1 – 3 . However, the…”
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Midwives' attitudes towards giving weight-related advice to obese pregnant women
Published in British journal of midwifery (01-04-2014)“…It is estimated that 1 in 5 pregnant women are obese, this poses a significant risk to maternal, fetal and newborn mortality and morbidity and as such,…”
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4
New Superfamily Members Identified for Schiff-Base Enzymes Based on Verification of Catalytically Essential Residues
Published in Biochemistry (Easton) (18-07-2006)“…Enzymes that utilize a Schiff-base intermediate formed with their substrates and that share the same α/β barrel fold comprise a mechanistically diverse…”
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Crystal Structure of Human Quinone Reductase Type 2, a Metalloflavoprotein
Published in Biochemistry (Easton) (03-08-1999)“…In mammals, two separate but homologous cytosolic quinone reductases have been identified: NAD(P)H:quinone oxidoreductase type 1 (QR1) (EC 1.6.99.2) and…”
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Structures of mammalian cytosolic quinone reductases
Published in Free radical biology & medicine (01-08-2000)“…The metabolism of quinone compounds presents one source of oxidative stress in mammals, as many pathways proceed by mechanisms that generate reactive oxygen…”
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Overview of protein structural and functional folds
Published in Current protocols in protein science (01-02-2004)“…This overview provides an illustrated, comprehensive survey of some commonly observed protein-fold families and structural motifs, chosen for their functional…”
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Abstract A012: Mre11 mediates cGAS activation and tumor suppression through ZBP1-dependent necroptosis in breast cancer
Published in Cancer research (Chicago, Ill.) (09-01-2024)“…Oncogene-induced replication stress leads to endogenous DNA damage, activating the cGAS/STING signaling pathway, a critical player in tumor suppression. The…”
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