Search Results - "Fortunato, Brad"

Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma by El Zarif, Talal, Semaan, Karl, Eid, Marc, Seo, Ji-Heui, Garinet, Simon, Davidsohn, Matthew P., Sahgal, Pranshu, Fortunato, Brad, Canniff, John, Nassar, Amin H., Abou Alaiwi, Sarah, Bakouny, Ziad, Lakshminarayanan, Gitanjali, Savignano, Hunter, Lyons, Kevin, Matar, Sayed, Ali, Atef, Saad, Eddy, Saliby, Renee Maria, Cordeiro, Paulo, Zhang, Ziwei, El Ahmar, Nourhan, Laimon, Yasmin Nabil, Labaki, Chris, Shah, Valisha, Freeman, Dory, O’Toole, Jillian, Lee, Gwo-Shu Mary, Hwang, Justin, Pomerantz, Mark, Signoretti, Sabina, Van Allen, Eliezer M., Xie, Wanling, Berchuck, Jacob E., Viswanathan, Srinivas R., Braun, David A., Choueiri, Toni K., Freedman, Matthew L., Baca, Sylvan C.

“…Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibitors (ICIs)…”
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Decoding the epigenetics and chromatin loop dynamics of androgen receptor-mediated transcription by Altıntaş, Umut Berkay, Seo, Ji-Heui, Giambartolomei, Claudia, Ozturan, Dogancan, Fortunato, Brad J., Nelson, Geoffrey M., Goldman, Seth R., Adelman, Karen, Hach, Faraz, Freedman, Matthew L., Lack, Nathan A.

“…Androgen receptor (AR)-mediated transcription plays a critical role in development and prostate cancer growth. AR drives gene expression by binding to…”
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Detection of neuroendocrine prostate cancer through plasma-based epigenomic profiling by Eid, Marc, Semaan, Karl, Seo, Ji-Heui, Davidsohn, Matthew P., Fortunato, Brad, Lakshminarayanan, Gitanjali, El Zarif, Talal, Savignano, Hunter, Canniff, John, Saliby, Renee Maria, Saad, Eddy, Pomerantz, Mark, Baca, Sylvan, Freedman, Matthew, Berchuck, Jacob E, Choueiri, Toni K.

“…201 Background: Neuroendocrine prostate cancer (NEPC) is an aggressive resistance phenotype that can develop in men with metastatic prostate adenocarcinoma…”
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43 Epigenomic profiling of translocation renal cell carcinoma via liquid biopsy by Garinet, Simon, Semaan, Karl, Canniff, John, Phillips, Noa, Davidsohn, Matthew, Berchuck, Jacob, Li, Jiao, Sadagopan, Ananthan, Fortunato, Brad, O’toole, Jillian, Gwo-shu, Mary, Horst, Jack, Freeman, Dory, Seo, Ji-Heui, Freedman, Matthew, Choueiri, Toni, Baca, Sylvan, Viswanathan, Srinivas

“…Abstract Background Translocation renal cell carcinoma (tRCC) is an aggressive subtype of kidney cancer usually driven by a fusion involving the TFE3 gene. Due…”
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Liquid biopsy epigenomic profiling for cancer subtyping by Baca, Sylvan C., Seo, Ji-Heui, Davidsohn, Matthew P., Fortunato, Brad, Semaan, Karl, Sotudian, Shahabbedin, Lakshminarayanan, Gitanjali, Diossy, Miklos, Qiu, Xintao, El Zarif, Talal, Savignano, Hunter, Canniff, John, Madueke, Ikenna, Saliby, Renee Maria, Zhang, Ziwei, Li, Rong, Jiang, Yijia, Taing, Len, Awad, Mark, Chau, Cindy H., DeCaprio, James A., Figg, William D., Greten, Tim F., Hata, Aaron N., Hodi, F. Stephen, Hughes, Melissa E., Ligon, Keith L., Lin, Nancy, Ng, Kimmie, Oser, Matthew G., Meador, Catherine, Parsons, Heather A., Pomerantz, Mark M., Rajan, Arun, Ritz, Jerome, Thakuria, Manisha, Tolaney, Sara M., Wen, Patrick Y., Long, Henry, Berchuck, Jacob E., Szallasi, Zoltan, Choueiri, Toni K., Freedman, Matthew L.

“…Although circulating tumor DNA (ctDNA) assays are increasingly used to inform clinical decisions in cancer care, they have limited ability to identify the…”
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Detection of sarcomatoid renal cell carcinoma using plasma cell-free DNA methylation by Semaan, Karl, El Zarif, Talal, Seo, Ji-Heui, Eid, Marc, Canniff, John, Fortunato, Brad, Savignano, Hunter, Davidsohn, Matthew P., Lakshminarayanan, Gitanjali, Saad, Eddy, Saliby, Renee Maria, Bakouny, Ziad, Matar, Sayed, Nuzzo, Pier Vitale, Berchuck, Jacob E, Signoretti, Sabina, Braun, David A., Freedman, Matthew, Baca, Sylvan, Choueiri, Toni K.

“…449 Background: Sarcomatoid differentiation (SD) in renal cell carcinoma (RCC) is associated with poor survival and heightened response to immune checkpoint…”
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Epigenomic profiling nominates master transcription factors (TFs) driving sarcomatoid differentiation (SD) of renal cell carcinoma (RCC) by El Zarif, Talal, Semaan, Karl, Eid, Marc, Fortunato, Brad, Nassar, Amin H, Abou Alaiwi, Sarah, Bakouny, Ziad, Shah, Valisha, Maria Saliby, Renee, Seo, Ji-Heui, Labaki, Chris, Saad, Eddy, Garinet, Simon, Matar, Sayed, Ahmar, Nourhan, Nabil Laimon, Yasmin, Mary Lee, Gwo-Shu, Pomerantz, Mark, E Berchuck, Jacob, Viswanathan, Srinivas R, Signoretti, Sabina, Van Allen, Eliezer M, Braun, David, K Choueiri, Toni, L Freedman, Matt, Baca, Sylvan S

“…Abstract Background Sarcomatoid differentiation of RCC (sRCC) is associated with poor survival. Recent studies showed marked response of sRCC to immune…”
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Detecting small cell transformation in patients with advanced EGFR mutant lung adenocarcinoma through epigenomic cfDNA profiling by El Zarif, Talal, Meador, Catherine B, Qiu, Xintao, Seo, Ji-Heui, Davidsohn, Matthew P, Savignano, Hunter, Lakshminarayanan, Gitanjali, McClure, Heather M, Canniff, John, Fortunato, Brad, Li, Rong, Banwait, Mandeep K, Semaan, Karl, Eid, Marc, Long, Henry, Hung, Yin P, Mahadevan, Navin R, Barbie, David A, Oser, Matthew G, Piotrowska, Zofia, Choueiri, Toni K, Baca, Sylvan C, Hata, Aaron N, Freedman, Matthew L, Berchuck, Jacob E

“…Histologic transformation to small cell lung cancer (SCLC) is a mechanism of treatment resistance in patients with advanced oncogene-driven lung adenocarcinoma…”
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Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping by Baca, Sylvan C., Seo, Ji-Heui, Davidsohn, Matthew P., Fortunato, Brad, Semaan, Karl, Sotudian, Shahabbedin, Lakshminarayanan, Gitanjali, Diossy, Miklos, Qiu, Xintao, El Zarif, Talal, Savignano, Hunter, Canniff, John, Madueke, Ikenna, Saliby, Renee Maria, Zhang, Ziwei, Li, Rong, Jiang, Yijia, Taing, Len, Awad, Mark, Chau, Cindy H., DeCaprio, James A., Figg, William D., Greten, Tim F., Hata, Aaron N., Hodi, F. Stephen, Hughes, Melissa E., Ligon, Keith L., Lin, Nancy, Ng, Kimmie, Oser, Matthew G., Meador, Catherine, Parsons, Heather A., Pomerantz, Mark M., Rajan, Arun, Ritz, Jerome, Thakuria, Manisha, Tolaney, Sara M., Wen, Patrick Y., Long, Henry, Berchuck, Jacob E., Szallasi, Zoltan, Choueiri, Toni K., Freedman, Matthew L.

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Abstract B035: Detection and monitoring of translocation renal cell carcinoma via epigenomic profiling of cell-free DNA by Garinet, Simon, Semaan, Karl, Caniff, John, Phillips, Noa, Berchuck, Jacob, Li, Jiao, Lyons, Kevin, Sadagopan, Ananthan, Fortunato, Brad, Lee, Mary, Horst, Jack, Trowbridge, Rachel, Seo, Ji-Heui, Freedman, Matthew, Choueiri, Toni, Baca, Sylvan, Viswanathan, Srinivas

“…Abstract We evaluated the ability of plasma chromatin immunoprecipitation and sequencing (ChIP-seq) and methylated DNA immunoprecipitation sequencing…”
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Abstract PS06-07: Liquid biopsy determination of HER2 status in breast cancer: results from a novel epigenomic platform by Parsons, Heather, Baca, Sylvan, D'Ippolito, Anthony, Jeong, Hyun-Hwan, Smith, Kalie, Tarantino, Paolo, Hughes, Melissa, Sendrick, Kerry, Painter, Corrie, Seo, Ji-Heui, Grant, Elizabeth, Guess, Jamey, Davidsohn, Matthew, Lakshminarayanan, Gitanjali, Strauss, Sarah, Savignano, Hunter, Canniff, John, Fortunato, Brad, Eaton, Matthew, Choueiri, Toni, Tolaney, Sara, Freedman, Matthew, Lin, Nancy

“…Abstract Background: Tumor HER2 status remains a critical predictive biomarker for patients with breast cancer given the availability of highly effective…”
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Abstract 963: Comprehensive epigenomic profiling from plasma to inform therapy selection: A proof-of-concept study in cancer by Clark, Travis, Seo, Ji-Heui, D'Ippolito, Anthony, Gorthi, Aparna, Beagan, Jonathan, Guess, Jamey, Donahue, Amy, Greene, Mandy, Lau, Alyssa, Ramirez, Fernando, Cibulskis, Kristian, Jeong, Hyun-Hwan, Davidsohn, Matthew, Lakshminarayanam, Gitanjali, Coyne, Michael, Tran, Baovy, Tamakloe, Tyrone, Sawaengsri, Hathairat, Eid, Marc, Semaan, Karl, Fortunato, Brad, Painter, Corrie A., Chmielecki, Juliann, Choueiri, Toni K., Barrett, J Carl, Otto, Geoff, Freedman, Matthew L., Eaton, Matthew L., Baca, Sylvan C.

“…Abstract BACKGROUND: Analysis of genomic alterations in circulating tumor DNA is gaining traction in clinical oncology and can provide insights into tumor…”
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Abstract A029: Epigenomic profiling nominates master transcription factors (TFs) driving sarcomatoid differentiation of renal cell carcinoma (RCC) by Semaan, Karl, Zarif, Talal El, Eid, Marc, Shah, Valisha, Fortunato, Brad, Saliby, Renee Maria, Nassar, Amin H., Alaiwi, Sarah Abou, Seo, Ji-Heui, Labaki, Chris, Bakouny, Ziad, Matar, Sayed, Ahmar, Nourhan El, Laimon, Yasmin Nabil, Lee, Gwo-Shu Mary, Pomerantz, Mark, Berchuck, Jacob, Signoretti, Sabina, Van Allen, Eliezer, Choueiri, Toni, Braun, David, Freedman, Matthew, Baca, Sylvan

“…Abstract Introduction Sarcomatoid RCC (sRCC) is associated with poor prognosis. Recent studies showed promising response rates of sRCC to immune checkpoint…”
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