Search Results - "Fortman, Jeffrey D"

Pleiotropic effects of interleukin-6 in a “two-hit” murine model of acute respiratory distress syndrome by Goldman, Julia L., Sammani, Saad, Kempf, Carrie, Saadat, Laleh, Letsiou, Eleftheria, Wang, Ting, Moreno-Vinasco, Liliana, Rizzo, Alicia N., Fortman, Jeffrey D., Garcia, Joe G. N.

“…Patients with acute respiratory distress syndrome (ARDS) exhibit elevated levels of interleukin-6 (IL-6), which correlate with increased morbidity and…”
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Assessment of Pain Associated with the Injection of Sodium Pentobarbital in Laboratory Mice (Mus musculus) by Dutton, John W, Artwohl, James E, Huang, Xichen, Fortman, Jeffrey D

“…The AVMA Guidelines for the Euthanasia of Animals considers injection of barbiturates to be an acceptable method of euthanasia in rodents but states there is a…”
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Evaluation of Effects of Laboratory Disinfectants on Mouse Gut Microbiota by Sciurba, Joseph D, Chlipala, George E, Green, Stefan J, Delaney, Martha A, Fortman, Jeffrey D, Purcell, Jeanette E

“…Disturbances in the gut microbiota are known to be associated with numerous human diseases. Mice have proven to be an invaluable tool for investigating the…”
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Behavioral Effects of Cage Size and Environmental Enrichment in New Zealand White Rabbits by Coda, Kathleen A, Fortman, Jeffrey D, García, Kelly D

“…One of the goals of environmental enrichment is to encourage species-typical behaviors, while discouraging abnormal behaviors or stereotypies. Assessing the…”
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Carriage of Methicillin-resistant Staphylococcus aureus in a Colony of Rhesus (Macaca mulatta) and Cynomolgus (Macaca fascicularis) Macaques by Greenstein, Abigail W, Boyle-Vavra, Susan, Maddox, Carol W, Tang, Xiwei, Halliday, Lisa C, Fortman, Jeffrey D

“…Methicillin-resistant Staphylococcus aureus (MRSA) carriage and infection are well documented in the human and veterinary literature; however only limited…”
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Evaluation of Analgesic Patches in Cynomolgus Macaques (Macaca fascicularis) by Smith, Alexandra A, Halliday, Lisa C, Lindeblad, Matthew O, Fortman, Jeffrey D

“…Opioids are widely used in veterinary and human medicine to manage pain. However, there is a paucity of information in the literature regarding the…”
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Reference Intervals for Total T4 and Free T4 in Cynomolgus Macaques (Macaca fascicularis) and Rhesus Macaques (Macaca mulatta) by Sciurba, Joseph D, Hayes, Jennifer M, Nouraie, Seyed Mehdi, Wilson, Heather M, Fortman, Jeffrey D, Halliday, Lisa C

“…Thyroid diseases, associated with either increased or decreased concentrations of circulating thyroid hormones, are prevalent in both human and veterinary…”
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Effects of Intracage Ammonia on Markers of Pulmonary Endothelial Integrity in Mice Housed in Static Microisolation Cages by Eichner, Michael, Purcell, Jeanette E, Fortman, Jeffrey D

“…Time-weighted exposure limits to ammonia are established for humans; however similar guidelines have not been defined for laboratory rodents. The Guide…”
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Epigenetic Contribution of the Myosin Light Chain Kinase Gene to the Risk for Acute Respiratory Distress Syndrome by Szilágyi, Keely L, Liu, Cong, Zhang, Xu, Wang, Ting, Fortman, Jeffrey D, Zhang, Wei, Garcia, Joe G.N

“…Abstract Acute respiratory distress syndrome (ARDS) is a devastating clinical syndrome with a considerable case fatality rate (∼30-40%). Health disparities…”
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Evaluation of Analgesic Efficacy of Meloxicam and 2 Formulations of Buprenorphine after Laparotomy in Female Sprague-Dawley Rats by Nunamaker, Elizabeth A, Goldman, Julia L, Adams, Cynthia R, Fortman, Jeffrey D

“…Managing postoperative pain in rodents is an important part of any animal care and use program, and identifying an optimal analgesic plan for a surgical…”
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Endpoint Refinement for Total Body Irradiation of C57BL/6 Mice by Nunamaker, Elizabeth A, Artwohl, James E, Anderson, Robert J, Fortman, Jeffrey D

“…Acute radiation syndrome is a life-threatening condition that has the potential to affect large populations of humans. Although several animal models of this…”
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The Effects of Water Volume and Bacterial Concentration on the Water Filtration Assay Used in Zebrafish Health Surveillance by Garcia, Kelly D, Coda, Kathleen A, Smith, Alexandra A, Condren, Alanna R, Deng, Yujia, Perkins, Cheryl, Sanchez, Laura M, Fortman, Jeffrey D

“…The number of zebrafish in biomedical research has increased exponentially over the past decades, leading to pressure onthe laboratory animal community to…”
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Inverse association between rural environment in infancy and sensitization to rodents in adulthood by Dorevitch, Samuel, MD, MPH, Tharenos, Leslie, MD, MPH, Demirtas, Hakan, PhD, Persky, Victoria, MD, Artwohl, James, DVM, Fortman, Jeffrey D., DVM

“…Background It is not known whether early childhood exposure to hygiene hypothesis factors modifies the risk of sensitization to aeroallergens among adults…”
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Effects of weekly blood collection in C57BL/6 mice by Raabe, Brigitte M, Artwohl, James E, Purcell, Jeanette E, Lovaglio, Jamie, Fortman, Jeffrey D

“…We assessed hematologic recovery, body weight, and behavior after serial blood collection in 10- to 14-wk-old C57BL/6 mice. Male and female mice (5 to 11 mice…”
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Pharmacokinetics of 2 Formulations of Buprenorphine in Macaques (Macaca mulatta and Macaca fascicularis) by Nunamaker, Elizabeth A, Halliday, Lisa C, Moody, David E, Fang, Wenfang B, Lindeblad, Matthew, Fortman, Jeffrey D

“…Buprenorphine is the cornerstone of pain management in nonhuman primates, but the pharmacokinetics of this widely used drug are unknown. The purpose of this…”
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Bordetella pseudohinzii as a Confounding Organism in Murine Models of Pulmonary Disease by Clark, Sarah E, Purcell, Jeanette E, Sammani, Saad, Steffen, Earl K, Crim, Marcus J, Livingston, Robert S, Besch-Williford, Cynthia, Fortman, Jeffrey D

“…A group studying acute lung injury observed an increased percentage of neutrophils in the bronchoalveolar lavage (BAL) fluid of mice. BAL was performed, and…”
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Cross-Foster Rederivation Compared with Antibiotic Administration in the Drinking Water to Eradicate Bordetella pseudohinzii by Clark, Sarah E, Purcell, Jeanette E, Bi, Xuan, Fortman, Jeffrey D

“…Bordetella pseudohinzii is a microbial agent of potential importance in mice and has confounded pulmonary research at our institution. The purpose of this…”
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Predictive Observation-Based Endpoint Criteria for Mice Receiving Total Body Irradiation by Nunamaker, Elizabeth A, Anderson, Robert J, Artwohl, James E, Lyubimov, Alexander V, Fortman, Jeffrey D

“…Total body irradiation of mice is a commonly used research technique; however, humane endpoints have not been clearly identified. This situation has led to the…”
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Effects of Weekly Blood Collection in Male and Female Cynomolgus Macaques (Macaca fascicularis) by Adams, Cynthia R, Halliday, Lisa C, Nunamaker, Elizabeth A, Fortman, Jeffrey D

“…This study was designed to evaluate the maximal amount of blood that can be safely collected in healthy, adult male and female cynomolgus macaques for 4…”
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Case Study: Polycystic Livers in a Transgenic Mouse Line by Lovaglio, Jamie, Artwohl, James E, Ward, Christopher J, Diekwisch, Thomas GH, Ito, Yoshihiro, Fortman, Jeffrey D

“…Three mice (2 male, 1 female; age, 5 to 16 mo) from a mouse line transgenic for keratin 14 (K14)-driven LacZ expression and on an outbred Crl:CD1(ICR)…”
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