Search Results - "Fortin, David"
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Recognition of white matter bundles using local and global streamline-based registration and clustering
Published in NeuroImage (Orlando, Fla.) (15-04-2018)“…Virtual dissection of diffusion MRI tractograms is cumbersome and needs extensive knowledge of white matter anatomy. This virtual dissection often requires…”
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Superior Longitudinal Fasciculus: A Review of the Anatomical Descriptions With Functional Correlates
Published in Frontiers in neurology (27-04-2022)“…The superior longitudinal fasciculus (SLF) is part of the longitudinal association fiber system, which lays connections between the frontal lobe and other…”
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Drug Delivery Technology to the CNS in the Treatment of Brain Tumors: The Sherbrooke Experience
Published in Pharmaceutics (27-05-2019)“…Drug delivery to the central nervous system (CNS) remains a challenge in neuro-oncology. Despite decades of research in this field, no consensus has emerged as…”
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Chemotherapy Delivery Strategies to the Central Nervous System: neither Optional nor Superfluous
Published in Current cancer drug targets (01-11-2015)“…Malignant brain tumors including primary brain tumors (e.g., glioblastoma multiforme) and metastases, are aggressive and lethal entities for the majority of…”
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Differential Expression and Clinical Significance of Transforming Growth Factor-Beta Isoforms in GBM Tumors
Published in International journal of molecular sciences (08-04-2018)“…Glioblastoma (GBM) represents the most common and aggressive malignant primary brain tumors in adults. Response to standard treatment is transitory and the…”
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Chemoattraction of Neoplastic Glial Cells with CXCL10, CCL2 and CCL11 as a Paradigm for a Promising Therapeutic Approach for Primary Brain Tumors
Published in International journal of molecular sciences (10-11-2021)“…Chemoattraction is a normal and essential process, but it can also be involved in tumorigenesis. This phenomenon plays a key role in glioblastoma (GBM). The…”
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Interactivity and vividness effects on social presence and involvement with a web-based advertisement
Published in Journal of business research (01-03-2005)“…This article measures the effects of various levels of interactivity and vividness of a message on attitudes and behavioral intentions within a web-based…”
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Machine learning classifiers for attributing tephra to source volcanoes: an evaluation of methods for Alaska tephras
Published in Journal of quaternary science (01-01-2020)“…ABSTRACT Glass composition‐based correlations of volcanic ash (tephra) traditionally rely on extensive manual plotting. Many previous statistical methods for…”
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The role of diffusion tractography in refining glial tumor resection
Published in Brain Structure and Function (01-05-2020)“…Primary brain tumors are notoriously hard to resect surgically. Due to their infiltrative nature, finding the optimal resection boundary without damaging…”
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Active delineation of Meyer's loop using oriented priors through MAGNEtic tractography (MAGNET)
Published in Human brain mapping (01-01-2017)“…Streamline tractography algorithms infer connectivity from diffusion MRI (dMRI) by following diffusion directions which are similarly aligned between…”
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P056: Three-dimensional nuclear telomere remodeling defines mechanisms of recurrence in glioblastomas
Published in Genetics in Medicine Open (2023)Get full text
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Impact of Drug Size on Brain Tumor and Brain Parenchyma Delivery after a Blood–Brain Barrier Disruption
Published in Journal of cerebral blood flow and metabolism (01-05-2014)“…Drug delivery to the brain is influenced by the blood–brain barrier (BBB) and blood–tumor barrier (BTB) to an extent that is still debated in neuro-oncology…”
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Transforming growth factor-beta and its implication in the malignancy of gliomas
Published in Targeted oncology (01-03-2015)“…Malignant gliomas are the most common type of primary malignant brain tumors. They are characterized by enhanced growing capabilities, neoangiogenic…”
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Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats
Published in Journal of nanobiotechnology (05-10-2018)“…Effectiveness of chemotherapy for treating glioblastoma (GBM) brain tumors is hampered by the blood-brain barrier which limits the entry into the brain of most…”
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A Drug-Eluting Injectable NanoGel for Localized Delivery of Anticancer Drugs to Solid Tumors
Published in Pharmaceutics (31-08-2023)“…Systemically administered chemotherapy reduces the efficiency of the anticancer agent at the target tumor tissue and results in distributed drug to non-target…”
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Three-Dimensional Nuclear Telomere Profiling as a Biomarker for Recurrence in Oligodendrogliomas: A Pilot Study
Published in International journal of molecular sciences (12-11-2020)“…Mechanisms of recurrence in oligodendrogliomas are poorly understood. Recurrence might be driven by telomere dysfunction-mediated genomic instability. In a…”
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Management of Primary Central Nervous System Lymphoma Using Intra-Arterial Chemotherapy With Osmotic Blood-Brain Barrier Disruption: Retrospective Analysis of the Sherbrooke Cohort
Published in Frontiers in oncology (20-01-2021)“…Primary central nervous system lymphomas (PCNSL) are rare and aggressive CNS tumors. Current management involves high-dose methotrexate (HD-MTX) typically…”
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Glioblastoma Treatment: Bypassing the Toxicity of Platinum Compounds by Using Liposomal Formulation and Increasing Treatment Efficiency With Concomitant Radiotherapy
Published in International journal of radiation oncology, biology, physics (01-09-2012)“…Purpose Treatments of glioblastoma with cisplatin or oxaliplatin only marginally improve the overall survival of patients and cause important side effects. To…”
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Quantitative Structure Retention Relationship Models in an Analytical Quality by Design Framework: Simultaneously Accounting for Compound Properties, Mobile-Phase Conditions, and Stationary-Phase Properties
Published in Industrial & engineering chemistry research (04-09-2013)“…Quantitative structure retention relationships (QSRRs) can play an important role in enhancing the speed and quality of chromatographic method development…”
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Seeing More by Showing Less: Orientation-Dependent Transparency Rendering for Fiber Tractography Visualization
Published in PloS one (07-10-2015)“…Fiber tractography plays an important role in exploring the architectural organization of fiber trajectories, both in fundamental neuroscience and in clinical…”
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