Search Results - "Fortes de Araujo, Fernanda"
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Development of an aptamer-based concentration method for the detection of Trypanosoma cruzi in blood
Published in PloS one (22-08-2012)“…Trypanosoma cruzi, a blood-borne parasite, is the etiological agent of Chagas disease. T. cruzi trypomastigotes, the infectious life cycle stage, can be…”
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New features on the survival of human-infective Trypanosoma rangeli in a murine model: Parasite accumulation is observed in lymphoid organs
Published in PLoS neglected tropical diseases (01-12-2020)“…Trypanosoma rangeli is a non-pathogenic protozoan parasite that infects mammals, including humans, in Chagas disease-endemic areas of South and Central…”
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3
Signatures of CD4 + T and B cells are associated with distinct stages of chronic chagasic cardiomyopathy
Published in Frontiers in immunology (25-04-2024)“…Chagas disease is a neglected parasitic disease caused by . While most patients are asymptomatic, around 30% develop Chronic Chagasic Cardiomyopathy (CCC)…”
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Human Chagas-Flow ATE-IgG1 for advanced universal and Trypanosoma cruzi Discrete Typing Units-specific serodiagnosis of Chagas disease
Published in Scientific reports (06-08-2020)“…The molecular and serological methods available for Discrete Typing Units (DTU)-specific diagnosis of Trypanosoma cruzi in chronic Chagas disease present…”
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Antigenic diversity of MASP gene family of Trypanosoma cruzi
Published in Microbes and infection (01-09-2022)“…Trypanosoma cruzi, the etiological agent of Chagas disease (CD), is a heterogeneous species with high genetic and phenotypic diversity. MASP is the second…”
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Aptamer based, non-PCR, non-serological detection of Chagas disease biomarkers in Trypanosoma cruzi infected mice
Published in PLoS neglected tropical diseases (01-01-2014)“…Chagas disease affects about 5 million people across the world. The etiological agent, the intracellular parasite Trypanosoma cruzi (T. cruzi), can be…”
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7
Immune response profiles from humans experimentally exposed to Phlebotomus duboscqi bites
Published in Frontiers in immunology (03-04-2024)“…Cutaneous leishmaniasis is a neglected vector-borne parasitic disease prevalent in 92 countries with approximately one million new infections annually…”
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Trypanosoma cruzi antigen detection in blood to assess treatment efficacy and cure in mice models of Chagas disease
Published in Frontiers in immunology (2023)“…Chagas disease (CD) is caused by the protozoan parasite . Although endemic mainly in Latin America, CD has become a global public health problem due to…”
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Potential Biomarkers for Asymptomatic Visceral Leishmaniasis among Iraq-Deployed U.S. Military Personnel
Published in Pathogens (Basel) (12-05-2023)“…Visceral leishmaniasis (VL) is a chronic infection caused by ( .) or parasites. Despite having the infection, most individuals never develop the clinical…”
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Identification of Anti-Trypanosoma cruzi Lead Compounds with Putative Immunomodulatory Activity
Published in Antimicrobial agents and chemotherapy (01-04-2018)“…In seeking substitutions for the current Chagas disease treatment, which has several relevant side effects, new therapeutic candidates have been extensively…”
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Methods Applied to the Diagnosis of Cattle Trypanosoma vivax Infection: An Overview of the Current State of the Art
Published in Current pharmaceutical biotechnology (01-01-2023)“…Bovine trypanosomiasis caused by Trypanosoma vivax is a relevant disease in domestic ungulates in Latin America, causing different types of livestock losses,…”
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Chagasic cardiomyopathy is marked by a unique signature of activated CD4 + T cells
Published in Journal of translational medicine (30-11-2022)“…Chagas disease is a neglected tropical disease in Latin America and an imported emerging disease worldwide. Chronic Chagas disease cardiomyopathy (CCC) is the…”
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Aptamer-based detection of disease biomarkers in mouse models for chagas drug discovery
Published in PLoS neglected tropical diseases (01-01-2015)“…Drug discovery initiatives, aimed at Chagas treatment, have been hampered by the lack of standardized drug screening protocols and the absence of simple…”
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Matrix Metalloproteinases 2 and 9 Are Differentially Expressed in Patients with Indeterminate and Cardiac Clinical Forms of Chagas Disease
Published in Infection and Immunity (01-10-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Accomplishing the genotype-specific serodiagnosis of single and dual Trypanosoma cruzi infections by flow cytometry Chagas-Flow ATE-IgG2a
Published in PLoS neglected tropical diseases (20-02-2018)“…The methods currently available for genotype-specific diagnosis of T. cruzi infection still present relevant limitations, especially to identify mixed…”
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CXCL9 and CXCL10 display an age-dependent profile in Chagas patients: a cohort study of aging in Bambui, Brazil
Published in Infectious diseases of poverty (11-05-2020)“…Chagas disease is endemic in Latin America and still represents an important public health problem in the region. Chronic cardiomyopathy is the most…”
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FC-TRIPLEX Chagas/Leish IgG1: a multiplexed flow cytometry method for differential serological diagnosis of chagas disease and leishmaniasis
Published in PloS one (15-04-2015)“…Differential serological diagnosis of Chagas disease and leishmaniasis is difficult owing to cross-reactivity resulting from the fact that the parasites that…”
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Regulatory T cells phenotype in different clinical forms of Chagas' disease
Published in PLoS neglected tropical diseases (01-05-2011)“…CD25(High) CD4+ regulatory T cells (Treg cells) have been described as key players in immune regulation, preventing infection-induced immune pathology and…”
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Profile of central and effector memory T cells in the progression of chronic human chagas disease
Published in PLoS neglected tropical diseases (09-09-2009)“…Chronic Chagas disease presents several different clinical manifestations ranging from asymptomatic to severe cardiac and/or digestive clinical forms. Several…”
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Characterization of the presence of Foxp3+ T cells from patients with different clinical forms of Chagas' disease
Published in Human pathology (01-02-2011)Get full text
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