Search Results - "Forsyth, Rebecca J"
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Characterization of the Invasive, Multidrug Resistant Non-typhoidal Salmonella Strain D23580 in a Murine Model of Infection
Published in PLoS neglected tropical diseases (01-06-2015)“…A distinct pathovar of Salmonella enterica serovar Typhimurium, ST313, has emerged in sub-Saharan Africa as a major cause of fatal bacteremia in young children…”
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Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium
Published in NPJ microgravity (09-03-2021)“…Spaceflight uniquely alters the physiology of both human cells and microbial pathogens, stimulating cellular and molecular changes directly relevant to…”
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Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns
Published in NPJ microgravity (28-02-2017)“…Three-dimensional models of human intestinal epithelium mimic the differentiated form and function of parental tissues often not exhibited by two-dimensional…”
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Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age
Published in Infection and immunity (01-11-2018)“…Tissues and organs provide the structural and biochemical landscapes upon which microbial pathogens and commensals function to regulate health and disease…”
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Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction Between Salmonella and a 3-D Biomimetic Intestinal Co-Culture Model
Published in Frontiers in cellular and infection microbiology (31-05-2022)“…Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian…”
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Role of RpoS in regulating stationary phase Salmonella Typhimurium pathogenesis-related stress responses under physiological low fluid shear force conditions
Published in mSphere (01-08-2022)“…The discovery that biomechanical forces regulate microbial virulence was established with the finding that physiological low fluid shear (LFS) forces altered…”
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