Search Results - "Forsell, Mattias N E"

Semimethylation is a feature of diffuse large B-cell lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere length by Carlund, Olivia, Thörn, Elina, Osterman, Pia, Fors, Maja, Dernstedt, Andy, Forsell, Mattias N E, Erlanson, Martin, Landfors, Mattias, Degerman, Sofie, Hultdin, Magnus

“…Large B-cell lymphoma (LBCL) is the most common lymphoma and is known to be a biologically heterogeneous disease regarding genetic, phenotypic, and clinical…”
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Recall of preexisting cross-reactive B cell memory after Omicron BA.1 breakthrough infection by Kaku, Chengzi I, Bergeron, Alan J, Ahlm, Clas, Normark, Johan, Sakharkar, Mrunal, Forsell, Mattias N E, Walker, Laura M

“…Understanding immune responses after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection will facilitate the development of…”
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Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein by MÖRNER, Andreas, DOUAGI, Iyadh, MASCOLA, John R, WYATT, Richard T, KARLSSON HEDESTAM, Gunilla B, FORSELL, Mattias N. E, SUNDLING, Christopher, DOSENOVIC, Pia, O'DELL, Sijy, DEY, Barna, KWONG, Peter D, VOSS, Gerald, THORSTENSSON, Rigmor

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Influence of Novel CD4 Binding-Defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T-Cell Responses in Nonhuman Primates by DOUAGI, Iyadh, FORSELL, Mattias N. E, WYATT, Richard T, KARLSSON HEDESTAM, Gunilla B, SUNDLING, Christopher, O'DELL, Sijy, YU FENG, DOSENOVIC, Pia, YUXING LI, SEDER, Robert, LORE, Karin, MASCOLA, John R

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Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages by Chernyshev, Mark, Sakharkar, Mrunal, Connor, Ruth I., Dugan, Haley L., Sheward, Daniel J., Rappazzo, C. G., Stålmarck, Aron, Forsell, Mattias N. E., Wright, Peter F., Corcoran, Martin, Murrell, Ben, Walker, Laura M., Karlsson Hedestam, Gunilla B.

“…Vaccination of SARS-CoV-2 convalescent individuals generates broad and potent antibody responses. Here, we isolate 459 spike-specific monoclonal antibodies…”
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Serum concentration of extracellular cold-inducible RNA-binding protein is associated with respiratory failure in COVID-19 by Schagatay, Felix, Diamant, Klara, Lidén, Mats, Edin, Alicia, Athlin, Simon, Hultgren, Olof, Ahlm, Clas, Forsell, Mattias N E, Savilampi, Johanna, Normark, Johan, Lange, Anna, Cajander, Sara

“…Uncontrolled release of damage-associated molecular patterns (DAMPs) is suggested to be a major trigger for the dysregulated host immune response that leads to…”
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Immune response to SARS-CoV-2 mRNA vaccination in multiple sclerosis patients after rituximab treatment interruption by Gröning, Remigius, Dernstedt, Andy, Ahlm, Clas, Normark, Johan, Sundström, Peter, Forsell, Mattias N E

“…Peripheral B cell depletion anti-CD20 treatment is a highly effective disease-modifying treatment for reducing new relapses in multiple sclerosis (MS)…”
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SARS-CoV-2 infection induces hyaluronan production in vitro and hyaluronan levels in COVID-19 patients relate to morbidity and long-term lung impairment: a prospective cohort study by Hellman, Urban, Rosendal, Ebba, Lehrstrand, Joakim, Henriksson, Johan, Björsell, Tove, Wennemo, Alfred, Hahn, Max, Österberg, Björn, Dorofte, Luiza, Nilsson, Emma, Forsell, Mattias N E, Smed-Sörensen, Anna, Lange, Anna, Karlsson, Mats G, Ahlm, Clas, Blomberg, Anders, Cajander, Sara, Ahlgren, Ulf, Lind, Alicia, Normark, Johan, Överby, Anna K, Lenman, Annasara

“…We previously demonstrated that the lungs of deceased COVID-19 patients were filled with a clear hydrogel consisting of hyaluronan (HA). In this translational…”
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Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis by Dernstedt, Andy, Leidig, Jana, Holm, Anna, Kerkman, Priscilla F, Mjösberg, Jenny, Ahlm, Clas, Henriksson, Johan, Hultdin, Magnus, Forsell, Mattias N E

“…Germinal centers (GC) are sites for extensive B cell proliferation and homeostasis is maintained by programmed cell death. The complement regulatory protein…”
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Humoral Responses against Coimmunized Protein Antigen but Not against Alphavirus-Encoded Antigens Require Alpha/Beta Interferon Signaling by HIDMARK, Asa S, NORDSTRÖM, Eva K. L, DOSENOVIC, Pia, FORSELL, Mattias N. E, LILJESTRÖM, Peter, KARLSSON HEDESTAM, Gunilla B

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Biochemical and Immunogenic Characterization of Soluble Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers Expressed by Semliki Forest Virus by Forsell, Mattias N E, Li, Yuxing, Sundbäck, Maria, Svehla, Krisha, Liljeström, Peter, Mascola, John R, Wyatt, Richard, Karlsson Hedestam, Gunilla B

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Deletion of Wiskott–Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells by Baptista, Marisa A. P., Keszei, Marton, Oliveira, Mariana, Sunahara, Karen K. S., Andersson, John, Dahlberg, Carin I. M., Worth, Austen J., Liedén, Agne, Kuo, I-Chun, Wallin, Robert P. A., Snapper, Scott B., Eidsmo, Liv, Scheynius, Annika, Karlsson, Mikael C. I., Bouma, Gerben, Burns, Siobhan O., Forsell, Mattias N. E., Thrasher, Adrian J., Nylén, Susanne, Westerberg, Lisa S.

“…Wiskott–Aldrich syndrome (WAS) is caused by loss-of-function mutations in the WASp gene. Decreased cellular responses in WASp-deficient cells have been…”
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High prevalence of persistent symptoms and reduced health-related quality of life 6 months after COVID-19 by Ahmad, Irma, Edin, Alicia, Granvik, Christoffer, Kumm Persson, Lowa, Tevell, Staffan, Månsson, Emeli, Magnuson, Anders, Marklund, Ingela, Persson, Ida-Lisa, Kauppi, Anna, Ahlm, Clas, Forsell, Mattias N E, Sundh, Josefin, Lange, Anna, Cajander, Sara, Normark, Johan

“…The long-term sequelae after COVID-19 constitute a challenge to public health and increased knowledge is needed. We investigated the prevalence of…”
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Immunization of Macaques With Soluble HIV Type 1 and Influenza Virus Envelope Glycoproteins Results in a Similarly Rapid Contraction of Peripheral B-Cell Responses After Boosting by Sundling, Christopher, Martinez, Paola, Soldemo, Martina, Spångberg, Mats, Bengtsson, Karin Lövgren, Stertman, Linda, Forsell, Mattias N. E., Hedestam, Gunilla B. Karlsson

“…The envelope glycoproteins (Env) represent a critical component of a successful antibody-mediated human immunodeficiency virus type 1 (HIV-1) vaccine. However,…”
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Regulation of Subunit-Specific Germinal Center B Cell Responses to the HIV-1 Envelope Glycoproteins by Antibody-Mediated Feedback by Forsell, Mattias N E, Kvastad, Linda, Sedimbi, Saikiran K, Andersson, John, Karlsson, Mikael C I

“…The regulation of germinal center (GC) B cell responses to single epitopes is well investigated. How monoclonal B cells are regulated within the polyclonal B…”
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Hierarchical Clustering and Trajectory Analyses Reveal Viremia-Independent B-Cell Perturbations in HIV-2 Infection by Johansson, Emil, Kerkman, Priscilla F, Scharf, Lydia, Lindman, Jacob, Szojka, Zsófia I, Månsson, Fredrik, Biague, Antonio, Medstrand, Patrik, Norrgren, Hans, Buggert, Marcus, Karlsson, Annika C, Forsell, Mattias N. E, Esbjörnsson, Joakim, Jansson, Marianne

“…Time to AIDS in HIV-2 infection is approximately twice as long compared to in HIV-1 infection. Despite reduced viremia, HIV-2-infected individuals display…”
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Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization by Dosenovic, Pia, Chakrabarti, Bimal, Soldemo, Martina, Douagi, Iyadh, Forsell, Mattias N. E, Li, Yuxing, Phogat, Adhuna, Paulie, Staffan, Hoxie, James, Wyatt, Richard T, Karlsson Hedestam, Gunilla B

“…The HIV-1 envelope glycoprotein (Env) functional spike has evolved multiple immune evasion strategies, and only a few broadly neutralizing determinants on the…”
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B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4 by Forsell, Mattias N E, Dey, Barna, Mörner, Andreas, Svehla, Krisha, O'dell, Sijy, Högerkorp, Carl-Magnus, Voss, Gerald, Thorstensson, Rigmor, Shaw, George M, Mascola, John R, Karlsson Hedestam, Gunilla B, Wyatt, Richard T

“…The surface HIV-1 exterior envelope glycoprotein, gp120, binds to CD4 on the target cell surface to induce the co-receptor binding site on gp120 as the initial…”
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Immunogenicity of HIV-1 envelope glycoprotein oligomers by Forsell, Mattias NE, Schief, William R, Wyatt, Richard T

“…PURPOSE OF REVIEWWe summarize and discuss recent developments regarding the immunogenicity of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein…”
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CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization by Sundling, Christopher, Schon, Karin, Morner, Andreas, Forsell, Mattias N. E, Wyatt, Richard T, Thorstensson, Rigmor, Hedestam, Gunilla B. Karlsson, Lycke, Nils Y

“…1 Swedish Institute for Infectious Disease Control, 171 82 Solna, Sweden 2 Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77…”
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