Search Results - "Forsberg, M."
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Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online
Published in Nature protocols (01-04-2018)“…This protocol describes XCMS Online, a web-based systems biology platform for processing of metabolomics data, pathway mapping and integration with genomics…”
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2
Molecular profiling of driver events in metastatic uveal melanoma
Published in Nature communications (20-04-2020)“…Metastatic uveal melanoma is less well understood than its primary counterpart, has a distinct biology compared to skin melanoma, and lacks effective…”
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3
Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood−brain barrier permeability: Possible link to postoperative delirium and cognitive decline
Published in Brain research (16-09-2015)“…Abstract A large percentage of patients subjected to general anesthesia at 65 years and older exhibit postoperative delirium (POD). Here, we test the…”
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4
Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine
Published in Pharmaceutical research (01-10-2013)“…ABSTRACT Purpose Drug delivery to the brain is impeded by the blood-brain barrier (BBB). Here, we attempted to enhance the brain uptake of cationic dopamine by…”
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5
Emission properties of Ga2O3 nano-flakes: effect of excitation density
Published in Scientific reports (08-02-2017)“…In the quest of developing high performance electronic and optical devices and more cost effective fabrication processes of monoclinic β-Ga 2 O 3 , new growth…”
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6
No distinct microbiome signature of irritable bowel syndrome found in a Swedish random population
Published in Gut (01-06-2020)“…The ethiopathogenesis of irritable bowel syndrome (IBS) is unknown. While a link to the gut microbiome is postulated, the heterogeneity of the healthy gut…”
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Species differences in the intra-brain distribution of an L-type amino acid transporter 1 (LAT1) -utilizing compound between mice and rats
Published in International journal of pharmaceutics (01-03-2021)“…[Display omitted] The prodrug approach targeting influx transporters has been extensively studied as a means of central nervous system drug delivery…”
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Comparison of seven different anesthesia protocols for nicotine pharmacologic magnetic resonance imaging in rat
Published in European neuropsychopharmacology (01-03-2016)“…Abstract Pharmacologic MRI (phMRI) is a non-invasive in vivo imaging method, which can evaluate the drug effects on the brain and provide complementary…”
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A Systematic Review and Meta-Analysis of the Efficacy and Safety of Rasagiline or Pramipexole in the Treatment of Early Parkinson’s Disease
Published in Parkinson's disease (16-01-2024)“…Background. Rasagiline or pramipexole monotherapy has been suggested for the management of early Parkinson’s disease (PD). The aim of this research was to…”
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10
Expression of pattern recognition receptors in porcine uterine epithelial cells in vivo and in culture
Published in Veterinary immunology and immunopathology (01-08-2018)“…•A number of pattern recognition receptors are expressed by porcine uterine epithelial cells.•TLR3 and TLR9 localize to the apical cell membrane and TLR4…”
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Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835
Published in Bioorganic & medicinal chemistry (01-11-2016)“…[Display omitted] The free fatty acid receptor 1 (FFA1), a G protein-coupled receptor (GPCR) naturally activated by long-chain fatty acids is a novel target…”
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12
Determining Minnesota bee species’ distributions and phenologies with the help of participatory science
Published in PeerJ (San Francisco, CA) (15-11-2023)“…The Minnesota Bee Atlas project contributed new information about bee distributions, phenologies, and community structure by mobilizing participatory science…”
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13
Development of a Novel Antibody-Drug Conjugate for the Potential Treatment of Ovarian, Lung, and Renal Cell Carcinoma Expressing TIM-1
Published in Molecular cancer therapeutics (01-12-2016)“…T-cell immunoglobulin and mucin domain 1 (TIM-1) is a type I transmembrane protein that was originally described as kidney injury molecule 1 (KIM-1) due to its…”
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Quality of endoscopic surveillance of Lynch syndrome patients in a Swedish cohort
Published in Endoscopy International Open (01-07-2024)“…Abstract Background and study aims Risk factors for colorectal cancer (CRC) in Lynch syndrome (LS) include sex, age, smoking, high body mass index (BMI),…”
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Treatment with Anti-HER2 Chimeric Antigen Receptor Tumor-Infiltrating Lymphocytes (CAR-TILs) Is Safe and Associated with Antitumor Efficacy in Mice and Companion Dogs
Published in Cancers (2023)“…Patients with metastatic melanoma have a historically poor prognosis, but recent advances in treatment options, including targeted therapy and immunotherapy,…”
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Endothelial damage, vascular bagging and remodeling of the microvascular bed in human microangiopathy with deep white matter lesions
Published in Acta neuropathologica communications (23-11-2018)“…White matter lesions (WMLs) are a common manifestation of small vessel disease (SVD) in the elderly population. They are associated with an enhanced risk of…”
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The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance
Published in Antioxidants (01-06-2023)“…Increased oxidative stress, dysfunctional cellular clearance, and chronic inflammation are associated with age-related macular degeneration (AMD). Prolyl…”
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Histological correlates of postmortem ultra-high-resolution single-section MRI in cortical cerebral microinfarcts
Published in Acta neuropathologica communications (13-03-2020)“…The identification of cerebral microinfarctions with magnetic resonance imaging (MRI) and histological methods remains challenging in aging and dementia. Here,…”
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Sustainable Hydrometallurgical Recovery of Valuable Elements from Spent Nickel–Metal Hydride HEV Batteries
Published in Metals (Basel ) (01-12-2018)“…In the present study, the recovery of valuable metals from a Panasonic Prismatic Module 6.5 Ah NiMH 7.2 V plastic casing hybrid electric vehicle (HEV) battery…”
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No support for lipid rescue in oral poisoning: A systematic review and analysis of 160 published cases
Published in Human & experimental toxicology (01-05-2017)“…Lipid rescue is used as treatment of various poisonings despite weak scientific evidence. Some experimental studies have indicated a positive effect, but…”
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