Search Results - "Forrest, Sally"

Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study by Meredith, Luke W, Hamilton, William L, Warne, Ben, Houldcroft, Charlotte J, Hosmillo, Myra, Jahun, Aminu S, Curran, Martin D, Parmar, Surendra, Caller, Laura G, Caddy, Sarah L, Khokhar, Fahad A, Yakovleva, Anna, Hall, Grant, Feltwell, Theresa, Forrest, Sally, Sridhar, Sushmita, Weekes, Michael P, Baker, Stephen, Brown, Nicholas, Moore, Elinor, Popay, Ashley, Roddick, Iain, Reacher, Mark, Gouliouris, Theodore, Peacock, Sharon J, Dougan, Gordon, Török, M Estée, Goodfellow, Ian

“…The burden and influence of health-care associated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the…”
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Ventilator-associated pneumonia in critically ill patients with COVID-19 by Maes, Mailis, Higginson, Ellen, Pereira-Dias, Joana, Curran, Martin D, Parmar, Surendra, Khokhar, Fahad, Cuchet-Lourenço, Delphine, Lux, Janine, Sharma-Hajela, Sapna, Ravenhill, Benjamin, Hamed, Islam, Heales, Laura, Mahroof, Razeen, Soderholm, Amelia, Forrest, Sally, Sridhar, Sushmita, Brown, Nicholas M, Baker, Stephen, Navapurkar, Vilas, Dougan, Gordon, Bartholdson Scott, Josefin, Conway Morris, Andrew

“…Pandemic COVID-19 caused by the coronavirus SARS-CoV-2 has a high incidence of patients with severe acute respiratory syndrome (SARS). Many of these patients…”
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Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales by Graf, Fabrice E., Goodman, Richard N., Gallichan, Sarah, Forrest, Sally, Picton-Barlow, Esther, Fraser, Alice J., Phan, Minh-Duy, Mphasa, Madalitso, Hubbard, Alasdair T. M., Musicha, Patrick, Schembri, Mark A., Roberts, Adam P., Edwards, Thomas, Lewis, Joseph M., Feasey, Nicholas A.

“…Infections with Enterobacterales (E) are increasingly difficult to treat due to antimicrobial resistance. After ceftriaxone replaced chloramphenicol (CHL) as…”
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Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections by Illingworth, Christopher Jr, Hamilton, William L, Warne, Ben, Routledge, Matthew, Popay, Ashley, Jackson, Chris, Fieldman, Tom, Meredith, Luke W, Houldcroft, Charlotte J, Hosmillo, Myra, Jahun, Aminu S, Caller, Laura G, Caddy, Sarah L, Yakovleva, Anna, Hall, Grant, Khokhar, Fahad A, Feltwell, Theresa, Pinckert, Malte L, Georgana, Iliana, Chaudhry, Yasmin, Curran, Martin D, Parmar, Surendra, Sparkes, Dominic, Rivett, Lucy, Jones, Nick K, Sridhar, Sushmita, Forrest, Sally, Dymond, Tom, Grainger, Kayleigh, Workman, Chris, Ferris, Mark, Gkrania-Klotsas, Effrossyni, Brown, Nicholas M, Weekes, Michael P, Baker, Stephen, Peacock, Sharon J, Goodfellow, Ian G, Gouliouris, Theodore, de Angelis, Daniela, Török, M Estée

“…SARS-CoV-2 is notable both for its rapid spread, and for the heterogeneity of its patterns of transmission, with multiple published incidences of…”
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Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19 by Jones, Nick K, Rivett, Lucy, Sparkes, Dominic, Forrest, Sally, Sridhar, Sushmita, Young, Jamie, Pereira-Dias, Joana, Cormie, Claire, Gill, Harmeet, Reynolds, Nicola, Wantoch, Michelle, Routledge, Matthew, Warne, Ben, Levy, Jack, Córdova Jiménez, William David, Samad, Fathima Nisha Begum, McNicholas, Chris, Ferris, Mark, Gray, Jane, Gill, Michael, Curran, Martin D, Fuller, Stewart, Chaudhry, Afzal, Shaw, Ashley, Bradley, John R, Hannon, Gregory J, Goodfellow, Ian G, Dougan, Gordon, Smith, Kenneth Gc, Lehner, Paul J, Wright, Giles, Matheson, Nicholas J, Baker, Stephen, Weekes, Michael P

“…Previously, we showed that 3% (31/1032)of asymptomatic healthcare workers (HCWs) from a large teaching hospital in Cambridge, UK, tested positive for…”
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Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii by Baker, Stephen, Krishna, Aishwarya, Higham, Sophie, Naydenova, Plamena, O’Leary, Siobhan, Scott, Josefin Bartholdson, Harcourt, Katherine, Forrest, Sally, Goulding, David, Thi Nguyen, To Nguyen, Toan, Nguyen Duc, Alekseeva, Elizaveta, Zhou, Qingqing, Andreozzi, Ilaria, Sobotic, Barbara, Craig, Hannah, Wong, Vivian, Forrest-Owen, Nichola, Sanchez, Dana Moreno, Pearce, Claire, Roberts, Leah, Watson, Simon, Clare, Simon, Torok, Mili Estee, Dougan, Gordon, Kellam, Paul, Tregoning, John S., Reece, Stephen T.

“…The use of monoclonal antibodies for the control of drug resistant nosocomial bacteria may alleviate a reliance on broad spectrum antimicrobials for treatment…”
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Inhibitory Concentrations of Ciprofloxacin Induce an Adaptive Response Promoting the Intracellular Survival of Salmonella enterica Serovar Typhimurium by Sridhar, Sushmita, Forrest, Sally, Pickard, Derek, Cormie, Claire, Lees, Emily A, Thomson, Nicholas R, Dougan, Gordon, Baker, Stephen

“…Antimicrobial resistance (AMR) is a pressing global health crisis, which has been fueled by the sustained use of certain classes of antimicrobials, including…”
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High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale by Sridhar, Sushmita, Forrest, Sally, Warne, Ben, Maes, Mailis, Baker, Stephen, Dougan, Gordon, Bartholdson Scott, Josefin

“…High-content imaging (HCI) is a technique for screening multiple cells in high resolution to detect subtle morphological and phenotypic variation. The method…”
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Correction to: Ventilator-associated pneumonia in critically ill patients with COVID-19 by Maes, Mailis, Higginson, Ellen, Pereira-Dias, Joana, Curran, Martin D, Parmar, Surendra, Khokhar, Fahad, Cuchet-Lourenço, Delphine, Lux, Janine, Sharma-Hajela, Sapna, Ravenhill, Benjamin, Hamed, Islam, Heales, Laura, Mahroof, Razeen, Soderholm, Amelia, Forrest, Sally, Sridhar, Sushmita, Brown, Nicholas M, Baker, Stephen, Navapurkar, Vilas, Dougan, Gordon, Scott, Josefn Bartholdson, Morris, Andrew Conway

“…An amendment to this paper has been published and can be accessed via the original article…”
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A metagenomic prospective cohort study on gut microbiome composition and clinical infection in small bowel transplantation by Madhav, Archana, Bousfield, Rachel, Pereira-Dias, Joana, Cormie, Claire, Forrest, Sally, Keane, Jacqueline, Kermack, Leanne, Higginson, Ellen, Dougan, Gordon, Spiers, Harry, Massey, Dunecan, Sharkey, Lisa, Rutter, Charlotte, Woodward, Jeremy, Russell, Neil, Amin, Irum, Butler, Andrew, Atkinson, Kayleigh, Dymond, Tom, Bartholdson Scott, Josefin, Baker, Stephen, Gkrania-Klotsas, Effrossyni

“…Two-thirds of small-bowel transplantation (SBT) recipients develop bacteremia, with the majority of infections occurring within 3 months post-transplant…”
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Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr by Agu, Chukwuma A., Soares, Filipa A.C., Alderton, Alex, Patel, Minal, Ansari, Rizwan, Patel, Sharad, Forrest, Sally, Yang, Fengtang, Lineham, Jonathan, Vallier, Ludovic, Kirton, Christopher M.

“…The collection sites of human primary tissue samples and the receiving laboratories, where the human induced pluripotent stem cells (hIPSCs) are derived, are…”
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A blueprint for the implementation of a validated approach for the detection of SARS-Cov2 in clinical samples in academic facilities by Sridhar, Sushmita, Forrest, Sally, Kean, Iain, Young, Jamie, Bartholdson Scott, Josefin, Maes, Mailis, Pereira-Dias, Joana, Parmar, Surendra, Routledge, Matthew, Sparkes, Dominic, Rivett, Lucy, Dougan, Gordon, Weekes, Michael, Curran, Martin, Goodfellow, Ian, Baker, Stephen

“…The COVID-19 pandemic is expanding at an unprecedented rate. As a result, diagnostic services are stretched to their limit, and there is a clear need for the…”
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Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia by Navapurkar, Vilas, Bartholdson Scott, Josefin, Maes, Mailis, Hellyer, Thomas P, Higginson, Ellen, Forrest, Sally, Pereira-Dias, Joana, Parmar, Surendra, Heasman-Hunt, Emma, Polgarova, Petra, Brown, Joanne, Titti, Lissamma, Smith, William PW, Scott, Jonathan, Rostron, Anthony, Routledge, Matthew, Sapsford, David, Török, M. Estée, McMullan, Ronan, Enoch, David A, Wong, Vanessa, Curran, Martin D, Brown, Nicholas M, Simpson, A John, Herre, Jurgen, Dougan, Gordon, Conway Morris, Andrew

“…Background: The diagnosis of pneumonia has been hampered by a reliance on bacterial cultures which take several days to return a result, and are frequently…”
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Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies by Collier, Dami A., De Marco, Anna, Ferreira, Isabella A. T. M., Meng, Bo, Datir, Rawlings P., Walls, Alexandra C., Kemp, Steven A., Bassi, Jessica, Pinto, Dora, Silacci-Fregni, Chiara, Bianchi, Siro, Tortorici, M. Alejandra, Bowen, John, Culap, Katja, Jaconi, Stefano, Cameroni, Elisabetta, Snell, Gyorgy, Pizzuto, Matteo S., Pellanda, Alessandra Franzetti, Garzoni, Christian, Riva, Agostino, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, McCoy, Laura E., Smith, Kenneth G. C., Bradley, John R., Temperton, Nigel, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Harvey, William, Virgin, Herbert W., Lanzavecchia, Antonio, Piccoli, Luca, Doffinger, Rainer, Wills, Mark, Veesler, David, Corti, Davide, Gupta, Ravindra K.

“…Transmission of SARS-CoV-2 is uncontrolled in many parts of the world; control is compounded in some areas by the higher transmission potential of the B.1.1.7…”
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The Removal of Airborne Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Other Microbial Bioaerosols by Air Filtration on Coronavirus Disease 2019 (COVID-19) Surge Units by Conway Morris, Andrew, Sharrocks, Katherine, Bousfield, Rachel, Kermack, Leanne, Maes, Mailis, Higginson, Ellen, Forrest, Sally, Pereira-Dias, Joana, Cormie, Claire, Old, Tim, Brooks, Sophie, Hamed, Islam, Koenig, Alicia, Turner, Andrew, White, Paul, Floto, R Andres, Dougan, Gordon, Gkrania-Klotsas, Effrossyni, Gouliouris, Theodore, Baker, Stephen, Navapurkar, Vilas

“…Abstract Airborne severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was detected in a coronavirus disease 19 (COVID-19) ward before activation of…”
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Development of caecaloids to study host–pathogen interactions: new insights into immunoregulatory functions of Trichuris muris extracellular vesicles in the caecum by Duque-Correa, María A., Schreiber, Fernanda, Rodgers, Faye H., Goulding, David, Forrest, Sally, White, Ruby, Buck, Amy, Grencis, Richard K., Berriman, Matthew

“…[Display omitted] •Development of new methods to generate, culture and characterise mouse caecaloids is described.•Caecaloids recapitulate the caecal…”
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Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells by Forbester, Jessica L., Lees, Emily A., Goulding, David, Forrest, Sally, Yeung, Amy, Speak, Anneliese, Clare, Simon, Coomber, Eve L., Mukhopadhyay, Subhankar, Kraiczy, Judith, Schreiber, Fernanda, Lawley, Trevor D., Hancock, Robert E. W., Uhlig, Holm H., Zilbauer, Matthias, Powrie, Fiona, Dougan, Gordon

“…Intestinal epithelial cells (IECs) play a key role in regulating immune responses and controlling infection. However, the direct role of IECs in restricting…”
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A2B-COVID: A Tool for Rapidly Evaluating Potential SARS-CoV-2 Transmission Events by Illingworth, Christopher J R, Hamilton, William L, Jackson, Christopher, Warne, Ben, Popay, Ashley, Meredith, Luke, Hosmillo, Myra, Jahun, Aminu, Fieldman, Tom, Routledge, Matthew, Houldcroft, Charlotte J, Caller, Laura, Caddy, Sarah, Yakovleva, Anna, Hall, Grant, Khokhar, Fahad A, Feltwell, Theresa, Pinckert, Malte L, Georgana, Iliana, Chaudhry, Yasmin, Curran, Martin, Parmar, Surendra, Sparkes, Dominic, Rivett, Lucy, Jones, Nick K, Sridhar, Sushmita, Forrest, Sally, Dymond, Tom, Grainger, Kayleigh, Workman, Chris, Gkrania-Klotsas, Effrossyni, Brown, Nicholas M, Weekes, Michael P, Baker, Stephen, Peacock, Sharon J, Gouliouris, Theodore, Goodfellow, Ian, Angelis, Daniela De, Török, M Estée

“…Abstract Identifying linked cases of infection is a critical component of the public health response to viral infectious diseases. In a clinical context, there…”
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Using Human Induced Pluripotent Stem Cell-derived Intestinal Organoids to Study and Modify Epithelial Cell Protection Against Salmonella and Other Pathogens by Lees, Emily A, Forbester, Jessica L, Forrest, Sally, Kane, Leanne, Goulding, David, Dougan, Gordon

“…The intestinal 'organoid' (iHO) system, wherein 3-D structures representative of the epithelial lining of the human gut can be produced from human induced…”
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Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study by Belay, Mulugeta, Tulu, Begna, Younis, Sidra, Jolliffe, David A, Tayachew, Dawit, Manwandu, Hana, Abozen, Tenagnework, Tirfie, Emawayish A, Tegegn, Metasebia, Zewude, Aboma, Forrest, Sally, Mayito, Jonathan, Huggett, Jim F, Jones, Gerwyn M, O'Sullivan, Denise M, Martineau, Henny M, Noursadeghi, Mahdad, Chandran, Aneesh, Harris, Kathryn A, Nikolayevskyy, Vlad, Demaret, Julie, Berg, Stefan, Vordermeier, Martin, Balcha, Taye T, Aseffa, Abraham, Ameni, Gobena, Abebe, Markos, Reece, Stephen T, Martineau, Adrian R

“…Haematopoietic stem cells expressing the CD34 surface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent…”
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