Search Results - "Forooshani, Ramin Sarrami"
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Vaginal bacterium Prevotella timonensis turns protective Langerhans cells into HIV‐1 reservoirs for virus dissemination
Published in The EMBO journal (04-10-2022)“…Dysbiosis of vaginal microbiota is associated with increased HIV‐1 acquisition, but the underlying cellular mechanisms remain unclear. Vaginal Langerhans cells…”
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Iron Oxychloride/Bovine Serum Albumin Nanosheets as Chemodynamic Therapy Agents
Published in Particle & particle systems characterization (01-12-2021)“…Iron oxychloride (FeOCl) is known for reactive oxygen species (ROS) generation through Fenton chemistry. The activity of FeOCl is preserved in the slightly…”
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Glycodendrimers prevent HIV transmission via DC-SIGN on dendritic cells
Published in International immunology (01-04-2013)“…Dendritic cells (DCs) are antigen-presenting cells efficient in capturing pathogens, and processing their antigenic determinants for presentation to…”
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HIV‐1 exposure and immune activation enhance sexual transmission of Hepatitis C virus by primary Langerhans cells
Published in Journal of the International AIDS Society (01-03-2019)“…Introduction The significant rise in incidence of Hepatitis C virus (HCV) infection among men‐who‐have‐sex‐with‐men (MSM) living with HIV‐1 suggests that HCV…”
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Clinical Applications and Anticancer Effects of Antimicrobial Peptides: From Bench to Bedside
Published in Frontiers in oncology (23-02-2022)“…Cancer is a multifaceted global health issue and one of the leading causes of death worldwide. In recent years, medical science has achieved great advances in…”
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Characterization of an engineered ACE2 protein for its improved biological features and its transduction into MSCs: A novel approach to combat COVID-19 infection
Published in International journal of biological macromolecules (01-10-2024)“…Transduced MSCs that express engineered ACE2 could be highly beneficial to combat COVID-19. Engineered ACE2 can act as decoy targets for the virus, preventing…”
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Cancer Immunotherapy Using Bioengineered Micro/Nano Structured Hydrogels
Published in Advanced healthcare materials (01-10-2023)“…Hydrogels, a class of materials with a 3D network structure, are widely used in various applications of therapeutic delivery, particularly cancer therapy…”
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HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3
Published in Nature immunology (01-02-2017)“…Gringhuis, Geijtenbeek and colleagues show that the RNA helicase DDX3 binds abortive HIV-1 RNA and induces type I interferon in dendritic cells, a process that…”
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Molecular analysis and phylogenetic characterization of HIV in Iran
Published in Journal of medical virology (01-07-2006)“…The rate of human immunodeficiency virus type 1 (HIV‐1) infection in Iran has increased dramatically in the last few years. While the earliest cases were found…”
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Phase I non-randomized clinical trial of allogeneic natural killer cells infusion in acute myeloid leukemia patients
Published in BMC cancer (10-11-2023)“…Abstract Introduction A new type of immune cell transplantation called allogeneic NK cell infusion is proposed as a potential universal off-the-shelf cell…”
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Human placenta-derived mesenchymal stem cells transplantation in patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 (phase I clinical trial): safety profile assessment
Published in Stem cell research & therapy (28-07-2022)“…Abstract Background High morbidity and mortality rates of the COVID-19 pandemic have made it a global health priority. Acute respiratory distress syndrome…”
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Immune activation of vaginal human Langerhans cells increases susceptibility to HIV-1 infection
Published in Scientific reports (25-02-2023)“…Vaginal inflammation increases the risk for sexual HIV-1 transmission but underlying mechanisms remain unclear. In this study we assessed the impact of immune…”
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Candidiasis in breast cancer: Tumor progression or not?
Published in Iranian journal of basic medical sciences (01-01-2024)“…is an "opportunistic fungal agent" in cancer patients that can become colonized in both mucosal and deep tissues and cause severe infections. Most evidence has…”
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Doxorubicin-loaded NK exosomes enable cytotoxicity against triple-negative breast cancer spheroids
Published in Iranian journal of basic medical sciences (01-01-2024)“…Objective(s): Natural killer (NK) cells are the most professional innate immune cells that initiate extracellular apoptosis via cytotoxic granules in malignant…”
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Safety and feasibility study of ex vivo expanded allogeneic-NK cells infusion in patients with acute pneumonia caused by COVID-19
Published in Pilot and feasibility studies (04-08-2023)“…NK cells are the most active innate immune cells in antiviral immunity, which are impaired by SARS-COV2 infection. Infusion of allogeneic NK cells might be a…”
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Healing Field: Using Alternating Electric Fields to Prevent Cytokine Storm by Suppressing Clonal Expansion of the Activated Lymphocytes in the Blood Sample of the COVID-19 Patients
Published in Frontiers in bioengineering and biotechnology (02-06-2022)“…In the case of the COVID-19 early diagnosis, numerous tech innovations have been introduced, and many are currently employed worldwide. But, all of the medical…”
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Cancer Is Associated with the Emergence of Placenta-Reactive Autoantibodies
Published in Biomedicines (23-01-2023)“…Placenta-specific antigens are minimally expressed or unexpressed in normal adult tissues, while they are widely expressed in cancer. In the course of…”
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Complete genomic sequence and phylogenetic relatedness of hepatitis B virus isolates from Iran
Published in Journal of medical virology (01-07-2005)“…Hepatitis B virus (HBV) is one of the main etiological agents of acute and chronic liver disease that is still a major public health problem in the world…”
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Genotype characterization and phylogenetic analysis of hepatitis B virus isolates from Iranian patients
Published in Journal of medical virology (01-02-2005)“…Hepatitis B virus (HBV) is one of the major causative agents of acute and chronic liver disease worldwide and is believed to be responsible for a million…”
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Hepatitis B virus genotyping, core promoter, and precore/core mutations among Afghan patients infected with hepatitis B: A preliminary report
Published in Journal of medical virology (01-03-2006)“…In spite of hepatitis B virus (HBV) vaccination, HBV infection remains an important public health problem worldwide. Although the HBV genotype distribution has…”
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