Search Results - "Formiga, Maria Nirvana Cruz"

Aortic dissection during antiangiogenic therapy with sunitinib. A case report by Formiga, Maria Nirvana da Cruz, Fanelli, Marcello Ferretti

“…Sunitinib is an antiangiogenic drug that has been approved for treating metastatic renal cancer. Its action as a tyrosine kinase inhibitor of vascular…”
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Expanding morphological and clinical aspects of hereditary leiomyomatosis and renal cell carcinoma (HLRCC): a case report in a patient with unusual morphology and clinical presentation by da Cunha, Isabela Werneck, da Costa, Walter Henriques, Morini, Mariana A., Bezerra, Stephania Martins, Carraro, Dirce Maria, Torrezan, Giovana Tardin, Formiga, Maria Nirvana Cruz, Guimaraes, Gustavo Cardoso, Zequi, Stenio Cassio, Soares, Fernando Augusto

“…Renal cell carcinoma (RCC) accounts for 2–3% of all malignant disease in adults. Hereditary RCC represents 5 to 8% of kidney tumors. Hereditary leiomyomatosis…”
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Germline DNA Damage Repair Gene Alterations in Patients with Metachronous Breast and Colorectal Cancer by Villacis, Rolando André Rios, Côrtes, Luiza, Basso, Tatiane Ramos, do Canto, Luisa Matos, Souza, Jeferson Santos, Aagaard, Mads Malik, da Cruz Formiga, Maria Nirvana, Aguiar, Jr, Samuel, Achatz, Maria Isabel, Rogatto, Silvia Regina

“…A hereditary component of breast (BC) and colorectal cancer (CRC) has been described in approximately one-third of these tumor types. BC patients have an…”
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BRCA1 deficiency is a recurrent event in early-onset triple-negative breast cancer: a comprehensive analysis of germline mutations and somatic promoter methylation by Brianese, Rafael Canfield, Nakamura, Kivvi Duarte de Mello, Almeida, Fernanda Gabriella dos Santos Ramos de, Ramalho, Rodrigo Fernandes, Barros, Bruna Durães de Figueiredo, Ferreira, Elisa Napolitano e, Formiga, Maria Nirvana da Cruz, de Andrade, Victor Piana, de Lima, Vladmir Claudio Cordeiro, Carraro, Dirce Maria

“…Purpose BRCA1 germline mutation is closely associated with triple-negative breast cancer. BRCA deficiency leads to impaired DNA repair and tumor development,…”
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Neoadjuvant hypofractionated radiotherapy and chemotherapy for extremity soft tissue sarcomas: Safety, feasibility, and early oncologic outcomes of a phase 2 trial by Gobo Silva, Maria Leticia, Lopes de Mello, Celso Abdon, Aguiar Junior, Samuel, D'Almeida Costa, Felipe, Stevanato Filho, Paulo Roberto, Santoro Bezerra, Tiago, Nakagawa, Suely Akiko, Nascimento, Antonio Geraldo, Werneck da Cunha, Isabela, Spencer Sobreira Batista, Ranyell Matheus, Nicolau Daher, Ulisses Ribaldo, Da Cruz Formiga, Maria Nirvana, Germano, Janaina Naiara, Catin Kupper, Bruna Elisa, De Assis Pellizzon, Antonio Cassio, Lopes, Ademar

“…•Neoadjuvant chemotherapy concomitant to hypofractionated radiotherapy is safe.•It provides excellent local control and a favorable toxicity profile.•Major…”
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Early-Onset Colorectal Cancer in Patients with Li Fraumeni Syndrome: Is It Really Enough to Justify Early Colon Cancer Screening? by Nirvana da Cruz Formiga, Maria, Ashton-Prolla, Patrícia, Alves de Souza Waddington Achatz, Maria Isabel

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Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil by Cotrim, Deborah Porto, Ribeiro, Adriana Regina Gonçalves, Paixão, Daniele, de Queiroz Soares, Diogo Cordeiro, Jbili, Rima, Pandolfi, Natasha Carvalho, Cezana, Camila, de Cássia Mauro, Carine, Mantoan, Henrique, Bovolim, Graziele, de Brot, Louise, Torrezan, Giovana Tardin, Carraro, Dirce Maria, Baiocchi, Glauco, da Cruz Formiga, Maria Nirvana, da Costa, Alexandre A B A

“…BRCA1/2 pathogenic (P) and likely pathogenic (LP) germline variants are frequent among patients with ovarian carcinoma. However, these variants have not been…”
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Frequency of Thyroid Carcinoma in Brazilian TP53 p.R337H Carriers With Li Fraumeni Syndrome by Formiga, Maria Nirvana da Cruz, de Andrade, Kelvin César, Kowalski, Luiz Paulo, Achatz, Maria Isabel

“…Li Fraumeni syndrome (LFS) is associated with a wide variety of tumors; nevertheless, thyroid carcinoma has not been evaluated in this syndrome. Due to the…”
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The repertoire of germline variants in patients with early‐onset rectal cancer by Beltrami, Caroline Moraes, do Canto, Luisa Matos, Villacis, Rolando André Rios, Petersen, Annabeth Høgh, Aagaard, Mads Malik, Cury, Sarah Santiloni, Formiga, Maria Nirvana da Cruz, Junior, Samuel Aguiar, Rogatto, Silvia Regina

“…Abbreviations APC APC regulator of WNT signaling pathway ATM ATM serine/threonine kinase BMPR1A bone morphogenetic protein receptor type 1A BRCA2 BRCA2 DNA…”
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Is early response by 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography a predictor of long-term outcome in patients with metastatic colorectal cancer? by Formiga, Maria Nirvana da Cruz, Fanelli, Marcello Ferretti, Dettino, Aldo Lourenço Abadde, Nicolau, Ulisses Ribaldo, Cavicchioli, Marcelo, Lima, Eduardo Nóbrega Pereira, de Mello, Celso Abdon Lopes

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Influence of access on survival of renal cancer in a Brazilian center by Leite, Luciana de Moura, Dettino, Aldo A., Rinck, José Augusto, Zequi, Stenio Cassio, Loose, Simone, Formiga, Maria Nirvana Cruz

“…Abstract only 644 Background: The introduction of tyrosine kinase inhibitors (TKI) and recently immunotherapy has brought major survival benefits for…”
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Abstract P6-08-34: Genetic testing for hereditary breast cancer in Brazilian public health system: The experience of tumor board reference in a cancer center by Carraro, Dirce M, Torrezan, Giovana T, Santiago, Karina M, da Cruz Formiga, Maria\ Nirvana, Sanches, Solange M, Makdissi, Fabiana BA

“…Introduction: In Brazil, genetic testing for hereditary cancer predisposition syndromes, including Hereditary Breast Cancer (HBC), is not covered by the public…”
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Analysis of prognostic biomarkers of response in patients with metastatic castration-resistant prostate cancer treated with abiraterone: A. C. Camargo Cancer Center experience by Silveira, Pedro Henrique Ferraro, Corassa, Marcelo, Lourenço Abbade Dettino, Aldo, Rinck, José Augusto, Oliveira, Thiago Bueno, Barbosa, Luiza Damian Ribeiro, Oliveira, Audrey, Formiga, Maria Nirvana Cruz

“…Abstract only 335 Background: Despite therapeutic progress in the management of advanced prostate cancer during the past decade, metastatic…”
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Molecular and clinical profile of Li-Fraumeni Syndrome in a Brazilian cohort by Formiga, Maria Nirvana Cruz, Nobrega, Amanda Franca, Santiago, Karina Miranda, Achatz, Maria Isabel Waddington

“…Abstract only…”
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Pre-treatment neutrophil to lymphocyte ratio (NLR) association with curative intent metastasectomy (MSX) in metastatic renal cell carcinoma (RCC) by Fares, Aline Fusco, Araujo, Daniel Vilarim, Ricardo, Eliza Dalsasso, Corassa, Marcelo, Formiga, Maria Nirvana Cruz, Costa, Walter Henriques, Guimaraes, Gustavo Cardoso, Zequi, Stenio C., Cunha, Isabela

“…Abstract only e16051 Background: NLR is a marker of inflammation and when elevated is associated with poor outcome in many tumors, including RCC. Hereby we…”
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Adjuvant radiation therapy in patients with breast cancer and Li-Fraumeni syndrome: Oncologic results and incidence of second neoplasms by Gondim, Guilherme Rocha Melo, Formiga, Maria Nirvana Cruz, Castro, Douglas Guedes, Silva, Maria Leticia GOBO, .Chen, Michael, Fogaroli, Ricardo, Ramos, Henderson, Coelho, Tharcisio Machado, Pellizzon, Antonio Cassio Assis, Da Costa, Alexandre Andre B. A.

“…Abstract only…”
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STAT-3 and Β-catenin expression in metastatic clear cell renal cell carcinoma (mRCC) by Fares, Aline Fusco, Cunha, Isabela, Araujo, Daniel Vilarim, Boente, Leonardo de Azevedo, Garcia, Daniel, Rinck, Jose A., Formiga, Maria Nirvana Cruz

“…Abstract only 583 Background: In mRCC, there are no prospectively validated biomarkers to guide the treatment and therapy decision is based on prognostic…”
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Analysis of predictive clinical markers of outcome in patients with metastatic clear-cell renal cell carcinoma (mRCC) treated with tyrosine-kinases inhibitors (TKI) in first line: A C Camargo Cancer Center experience by Ferreira, Camila Nassif Martins, Rinck, José Augusto, Albuquerque, Christiane Silveira Marinho, Costa, Tatiana Vieira, Urvanegia, Ana Claudia Machado, Corassa, Marcelo, Formiga, Maria Nirvana Cruz, Lourenço Abbade Dettino, Aldo, Tariki, Milena Shizue, Pinto, Flavio Augusto Ismael, Oliveira, Thiago Bueno, Salvadori, Marcela Marinelli

“…Abstract only 525 Background: TKI have improved the prognosis of patients with mRCC, but rarely lead to durable response. Predictive clinical biomarkers have…”
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Comparative analysis between the 8 th and 7 th AJCC as a prognostic tool for patients diagnosed with nonmetastatic head and neck soft-tissue sarcoma by Brito, Angelo Borsarelli Carvalho, Zanetta, Giulia Kodja, Costa, Felipe D'Almeida, Formiga, Maria Nirvana da Cruz, Mello, Celso Lopes, Filho, Joao Goncalves, Ikeda, Mauro Kazuo, Camillo, Cláudia Malheiros, Pinto, Clovis Antonio Lopes, de Jesus, Victor Hugo Fonseca, Campos, Fernando Augusto Batista, Kowalski, Luiz Paulo, Nicolau, Ulisses Ribaldo

“…e23550 Background: Head and neck soft-tissue sarcoma (HN-STS) is a rare entity for which a new prognostic risk stratification has been proposed in the 8th…”
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Bempegaldesleukin Plus Nivolumab Versus Sunitinib or Cabozantinib in Previously Untreated Advanced Clear Cell Renal Cell Carcinoma: A Phase III Randomized Study (PIVOT-09) by Tannir, Nizar M, Formiga, Maria Nirvana, Penkov, Konstantin, Kislov, Nikolay, Vasiliev, Aleksandr, Gunnar Skare, Nils, Hong, Walter, Dai, Stanley, Tang, Lily, Qureshi, Anila, Zalevsky, Jonathan, Tagliaferri, Mary A, George, Daniel, Agarwal, Neeraj, Pal, Sumanta

“…Bempegaldesleukin (BEMPEG) is a pegylated interleukin (IL)-2 cytokine prodrug engineered to provide controlled and sustained activation of the clinically…”
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