Search Results - "Forlani, Angelo"
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The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles
Published in Psychopharmacology (01-04-2005)“…Modulation of metabotropic glutamate receptor (mGluR) subtypes represents a novel approach for the treatment of neurological and psychiatric disorders. This…”
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Characterization of the potent and highly selective A2A receptor antagonists preladenant and SCH 412348 [7-[2-[4-2,4-difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in rodent models of movement disorders and depression
Published in The Journal of pharmacology and experimental therapeutics (01-07-2009)“…The adenosine A(2A) receptor has been implicated in the underlying biology of various neurological and psychiatric disorders, including Parkinson's disease…”
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Gene expression profiling of melanocortin system in neuropathic rats supports a role in nociception
Published in Brain research. Molecular brain research. (21-10-2003)“…The melanocortin (MC) system is involved in several biological functions. Its possible role in nociception has recently attracted attention in the field…”
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Lack of the nociceptin receptor does not affect acute or chronic nociception in mice
Published in Peptides (New York, N.Y. : 1980) (01-09-2002)“…The peptide nociceptin/orphanin FQ (N/OFQ) and its receptor ORL-1, also designated opioid receptor 4 (OP 4) are involved in the modulation of nociception…”
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The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents : a comparison of efficacy and side-effect profiles: Glutamate Receptor Subtypes: Promising New Pharmacotherapeutic Targets
Published in Psychopharmacologia (2005)Get full text
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HEMODYNAMIC CHANGES DO NOT MEDIATE THE CARDIOPROTECTION INDUCED BY THE A1, ADENOSINE RECEPTOR AGONIST CCPA IN THE RABBIT
Published in Pharmacological research (01-01-1997)“…Stimulation of adenosine A1receptors is known to reduce infarct size in the rabbit heart. The aim of the present study was to verify whether a protective…”
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Blockade of adenosine A2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats
Published in Neuroreport (01-12-1998)“…BLOCKADE of adenosine receptors can reduce cerebral infarct size in the model of global ischaemia. Using the potent and selective A2A adenosine receptor…”
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Cardiovascular pharmacology of the A2A adenosine receptor antagonist, SCH 58261, in the rat
Published in The Journal of pharmacology and experimental therapeutics (01-04-1998)“…We characterized the in vivo cardiovascular profile of SCH 58261, 7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2, 4-triazolo[1,5-c] pyrimidine, a…”
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Mechanism and Pressor Relevance of the Short-Term Cardiovascular and Renin Excitatory Actions of the Selective A2A-Adenosine Receptor Agonists
Published in Journal of cardiovascular pharmacology (01-09-1997)“…Selective A2A adenosine receptor agonists are potent vasodilators that reduce blood pressure and induce marked increments in heart rate and plasma renin…”
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5-Hydroxytryptamine induces contraction in isolated human mammary artery: effect of ketanserin
Published in Cardiovascular drugs and therapy (01-01-1990)“…5-hydroxytryptamine (5HT) treatment produced dose-related contractions in the human internal mammary artery with an EC50 value of 3.4 X 10(-7) M. The 5HT2…”
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