Search Results - "Forgács, L"

Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes by Forgacs, Agnes L, Dere, Edward, Angrish, Michelle M, Zacharewski, Timothy R

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-elicited time- and dose-dependent differential gene expression was compared in human, mouse, and rat primary…”
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Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water by KOPEC, Anna K, KIM, Suntae, FORGACS, Agnes L, ZACHAREWSKI, Timothy R, PROCTOR, Deborah M, HARRIS, Mark A, HAWS, Laurie C, THOMPSON, Chad M

“…Chronic administration of high doses of hexavalent chromium [Cr(VI)] as sodium dichromate dihydrate (SDD) elicits alimentary cancers in mice. To further…”
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o-p′-DDT-mediated uterotrophy and gene expression in immature C57BL/6 mice and Sprague–Dawley rats by Kwekel, Joshua C., Forgacs, Agnes L., Williams, Kurt J., Zacharewski, Timothy R.

“…1,1,1-Trichloro-2,2-bis(2-chlorophenyl-4-chlorophenyl)ethane (o,p′-DDT) is an organochlorine pesticide and endocrine disruptor known to activate the estrogen…”
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Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice by Fong, Cora J, Burgoon, Lyle D, Williams, Kurt J, Forgacs, Agnes L, Zacharewski, Timothy R

“…Uterine temporal and dose-dependent histopathologic, morphometric and gene expression responses to the selective estrogen receptor modulator tamoxifen (TAM)…”
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Effects of tamoxifen and ethynylestradiol cotreatment on uterine gene expression in immature, ovariectomized mice by Fong, Cora J, Burgoon, Lyle D, Williams, Kurt J, Jones, A Daniel, Forgacs, Agnes L, Zacharewski, Timothy R

“…Tamoxifen (TAM), the primary treatment for estrogen receptor (ER)-positive breast cancer, has been associated with an increased incidence of endometrial cancer…”
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Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver by Nault, Rance, Forgacs, Agnes L., Dere, Edward, Zacharewski, Timothy R.

“…•Gene expression elicited by AhR ligands TCDD, PCB126, βNF and ICZ was compared.•AhR ligands TCDD, PCB126, βNF and ICZ regulate a common subset of genes.•AhR…”
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Efficacy of humanized single large doses of caspofungin on the lethality and fungal tissue burden in a deeply neutropenic murine model against Candida albicans and Candida dubliniensis by Prépost, Eszter, Tóth, Zoltán, Perlin, David S, Gesztelyi, Rudolf, Kardos, Gábor, Kovács, Renátó, Nagy, Fruzsina, Forgács, Lajos, Majoros, László

“…Echinocandins are the first-line therapy for treatment of invasive infections, but the mortality rate remains high, calling for novel strategies. Giving single…”
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BLTK1 murine Leydig cells: a novel steroidogenic model for evaluating the effects of reproductive and developmental toxicants by Forgacs, Agnes L, Ding, Qi, Jaremba, Rosemary G, Huhtaniemi, Ilpo T, Rahman, Nafis A, Zacharewski, Timothy R

“…Leydig cells are the primary site of androgen biosynthesis in males. Several environmental toxicants target steroidogenesis resulting in both developmental and…”
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Triazine herbicides and their chlorometabolites alter steroidogenesis in BLTK1 murine Leydig cells by Forgacs, Agnes L, D'Souza, Michelle L, Huhtaniemi, Ilpo T, Rahman, Nafis A, Zacharewski, Timothy R

“…The triazine herbicides, atrazine (ATR), simazine (SIM), propazine (PRO), terbuthylazine (TBA), and their chlorinated metabolites have been implicated in the…”
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Tamoxifen-elicited uterotrophy: cross-species and cross-ligand analysis of the gene expression program by Kwekel, Joshua C, Forgacs, Agnes L, Burgoon, Lyle D, Williams, Kurt J, Zacharewski, Timothy R

“…Tamoxifen (TAM) is a well characterized breast cancer drug and selective estrogen receptor modulator (SERM) which also has been associated with a small…”
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Comparative Metabolomic and Genomic Analyses of TCDD-Elicited Metabolic Disruption in Mouse and Rat Liver by Forgacs, Agnes L., Kent, Michael N., Makley, Meghan K., Mets, Bryan, DelRaso, Nicholas, Jahns, Gary L., Burgoon, Lyle D., Zacharewski, Timothy R., Reo, Nicholas V.

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) elicits a broad spectrum of species-specific effects that have not yet been fully characterized. This study compares…”
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Genome-Wide Computational Analysis of Dioxin Response Element Location and Distribution in the Human, Mouse, and Rat Genomes by Dere, Edward, Forgacs, Agnes L, Zacharewski, Timothy R, Burgoon, Lyle D

“…The aryl hydrocarbon receptor (AhR) mediates responses elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin by binding to dioxin response elements (DRE) containing…”
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Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water by Kopec, Anna K., Kim, Suntae, Forgacs, Agnes L., Zacharewski, Timothy R., Proctor, Deborah M., Harris, Mark A., Haws, Laurie C., Thompson, Chad M.

“…Chronic administration of high doses of hexavalent chromium [Cr(VI)] as sodium dichromate dihydrate (SDD) elicits alimentary cancers in mice. To further…”
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Comparative toxicogenomic analysis of oral Cr(VI) exposure effects in rat and mouse small intestinal epithelia by Kopec, Anna K., Thompson, Chad M., Kim, Suntae, Forgacs, Agnes L., Zacharewski, Timothy R.

“…Continuous exposure to high concentrations of hexavalent chromium [Cr(VI)] in drinking water results in intestinal tumors in mice but not rats…”
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Effects of TCDD on the expression of nuclear encoded mitochondrial genes by Forgacs, Agnes L., Burgoon, Lyle D., Lynn, Scott G., LaPres, John J., Zacharewski, Timothy

“…Generation of mitochondrial reactive oxygen species (ROS) can be perturbed following exposure to environmental chemicals such as 2,3,7,8-tetrachlorodibenzo-…”
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Identification of aryl hydrocarbon receptor binding targets in mouse hepatic tissue treated with 2,3,7,8-tetrachlorodibenzo- p-dioxin by Lo, Raymond, Celius, Trine, Forgacs, Agnes L., Dere, Edward, MacPherson, Laura, Harper, Patricia, Zacharewski, Timothy, Matthews, Jason

“…Genome-wide, promoter-focused ChIP-chip analysis of hepatic aryl hydrocarbon receptor (AHR) binding sites was conducted in 8-week old female C57BL/6 treated…”
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[3H]noradrenaline-releasing action of vinpocetine in the isolated main pulmonary artery of the rabbit by Pauló, T, Tóth, P T, Nguyen, T T, Forgács, L, Török, T L, Magyar, K

“…Vinpocetine (10(-6)-3 X 10(-5) M) increased both the resting and the nerve stimulation-evoked release of [3H]noradrenaline from the isolated main pulmonary…”
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Studies on the efficacy of digoxin by GABOR, G, FORGACS, L

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The effect of left heart failure on the cardiac cycle by GABOR, G, FORGACS, L

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Rotational characteristics of the Warner-Lambert Softcon hydrophilic contact lenses by Forgacs, L S, Dudak, M G

“…The rotational characteristics of seven Warner-Lambert Softcon soft hydrophilic contact lenses were monitored on the subject's eye by direct observation and…”
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