Search Results - "Forestal, Colin A"
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Francisella tularensis Has a Significant Extracellular Phase in Infected Mice
Published in The Journal of infectious diseases (01-07-2007)“…The ability of Francisella tularensis to replicate in macrophages has led many investigators to assume that it resides primarily intracellularly in the blood…”
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Deletion of TolC Orthologs in Francisella tularensis Identifies Roles in Multidrug Resistance and Virulence
Published in Proceedings of the National Academy of Sciences - PNAS (22-08-2006)“…The Gram-negative bacterium Francisella tularensis is the causative agent of tularemia. Interest in this zoonotic pathogen has increased due to its…”
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The live vaccine strain of Francisella tularensis replicates in human and murine macrophages but induces only the human cells to secrete proinflammatory cytokines
Published in Journal of leukocyte biology (01-06-2005)“…Francisella tularensis is the highly infectious agent of tularemia, a disease that can prove fatal in humans. An attenuated live vaccine strain (LVS) of this…”
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Mac-1⁺ Cells Are the Predominant Subset in the Early Hepatic Lesions of Mice Infected with Francisella tularensis
Published in Infection and Immunity (01-12-2006)“…The cell composition of early hepatic lesions of experimental murine tularemia has not been characterized with specific markers. The appearance of multiple…”
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Francisella tularensis Selectively Induces Proinflammatory Changes in Endothelial Cells
Published in The Journal of immunology (1950) (01-09-2003)“…Naturally acquired infections with Francisella tularensis, the bacterial agent of tularemia, occur infrequently in humans. However, the high infectivity and…”
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A conserved and immunodominant lipoprotein of Francisella tularensis is proinflammatory but not essential for virulence
Published in Microbial pathogenesis (01-06-2008)“…Francisella tularensis is a highly virulent bacterium that causes tularemia, a disease that is often fatal if untreated. A live vaccine strain (LVS) of this…”
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Obviousness-type double patenting: who would have thought it would have such a profound effect on the pharmaceutical industry?
Published in Landslide (Chicago, Ill.) (01-09-2012)Get full text
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