Search Results - "Foreman, J. C."

Human basophil degranulation is not triggered by very dilute antiserum against human IgE by Hirst, S. J, Hayes, N. A, Burridge, J, Pearce, F. L, Foreman, J. C

“…We have attempted to reproduce the findings of Benveniste and co-workers, who reported in 1988 that degranulation of human basophil leukocytes is triggered by…”
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Calcitonin gene-related peptide, endothelin-1, the cutaneous microvasculature and Raynaud's phenomenon by BUNKER, C. B., GOLDSMITH, P. C., LESLIE, T. A., HAYES, N., FOREMAN, J. C., DOWD, P. M.

“…Summary It has been argued that the digital cutaneous microvasculature is the site of the anomaly which causes Raynaud's phenomenon (RP). Both endothelin‐1…”
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Neuropeptides and the pathogenesis of allergy by Foreman, J C

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Involvement of kinins in hyperresponsiveness induced by platelet activating factor in the human nasal airway by Turner, P J, Dear, J W, Foreman, J C

“…The aim of this study was to investigate the role of kinins in the development of nasal hyperresponsiveness induced by platelet activating factor (PAF) in…”
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Induction by inhibitors of nitric oxide synthase of hyperresponsiveness in the human nasal airway by Turner, P J, Maggs, J R L, Foreman, J C

“…The effects of inhibitors of nitric oxide synthase (NOS) on the responsiveness of the human nasal airway were investigated, by measuring the nasal response to…”
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Cutaneous Responses to Endothelin-1 and Histamine in Patients with Vibration White Finger by Dowd, Pauline M., Goldsmith, Portia C., Chopra, Sunil, Bull, Helen A., Foreman, John C.

“…Vibration white finger (VWF) is the episodic blanching of the fingers that occurs in response to cold in those who work with hand-held vibrating tools…”
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Structure-activity relationships for some substance P-related peptides that cause wheal and flare reactions in human skin by Foreman, J C, Jordan, C C, Oehme, P, Renner, H

“…Substance P (6.25-25 p-mole) produced dose-dependent flare and wheal responses when injected intradermally into the volar surface of the human forearm. The…”
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Some effects of calcitonin gene-related peptide in human skin and on histamine release by Piotrowski, W, Foreman, J C

“…Calcitonin gene-related peptide (CGRP) produced a dose-related wheal and flare reaction in human skin at doses of 12.5 to 50 pmol. The flare response but not…”
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Attenuation of human nasal airway responses to bradykinin and histamine by inhibitors of nitric oxide synthase by Dear, J.W., Ghali, S., Foreman, J.C.

“…1 The effects of inhibitors of nitric oxide synthase and local anaesthetics were studied on changes in human nasal airway patency and albumin extravasation in…”
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Reduction by Hoe 140, the B2 kinin receptor antagonist, of antigen‐induced nasal blockage by Austin, C.E., Foreman, J.C., Scadding, G.K.

“…In subjects with allergic rhinitis to house‐dust mite (HDM), antigen challenge produced a significant increase in nasal blockage but had no effect on nasal…”
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Substance P and calcitonin gene-related peptide: effects on mast cells and in human skin by Foreman, J C

“…Mast cells are found in close association with blood vessels, and histamine is known to be a potent vasodilator in humans. It is now clear that mast cells form…”
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Acoustic rhinometry compared with posterior rhinomanometry in the measurement of histamine‐ and bradykinin‐induced changes in nasal airway patency by Austin, CE, Foreman, JC

“…1. Acoustic rhinometry is a relatively new method for objectively assessing nasal airway patency. In this paper we compare acoustic rhinometry with active…”
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Hyperresponsiveness in the human nasal airway: new targets for the treatment of allergic airway disease by Turner, P J, Foreman, J C

“…ALLERGIC rhinitis is a condition which affects over 15% of the population in the United Kingdom. The pathological process involves two stages: nasal…”
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A study of the action of bradykinin and bradykinin analogues in the human nasal airway by Austin, C E, Foreman, J C

“…1. The aim of this study was to investigate the action of bradykinin on resistance to airflow and on vascular permeability in the human nasal airway, and to…”
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The effects of substance P on histamine and 5-hydroxytryptamine release in the rat by Fewtrell, C. M. S., Foreman, J. C., Jordan, C. C., Oehme, P., Renner, H., Stewart, J. M.

“…1. Substance P (SP) induces histamine release from isolated rat peritoneal mast cells at concentrations of 0·1-10 μM. 2. Inhibitors of glycolysis and…”
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Characterization of the bradykinin receptor in the human nasal airway using the binding of [125I]‐Hoe 140 by Dear, J.W., Wirth, K., Scadding, G.K., Foreman, J.C.

“…1 The aim of this study was to characterize the kinin receptor in the human nasal airway using [125I]‐Hoe 140 binding to a membrane preparation from human…”
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On the actions of substance P, somatostatin, and vasoactive intestinal polypeptide on rat peritoneal mast cells and in human skin by PIOTROWSKI, W, FOREMAN, J. C

“…Substance P (SP), somatostatin (Som), and vasoactive intestinal polypeptide (VIP) induced a concentration-dependent release of histamine from isolated rat…”
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IgE‐receptor activated chloride uptake in relation to histamine secretion from rat mast cells by Friis, U.G., Johansen, T., Hayes, N.A., Foreman, J.C.

“…1 Antigen‐stimulated histamine secretion from rat peritoneal mast cells was inhibited when extracellular chloride was replaced by either isethionate or…”
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Histamine release induced by Arg-Pro-Lys-Pro(CH2)11CH3 from rat peritoneal mast cells by Repke, H, Piotrowski, W, Bienert, M, Foreman, J C

“…The substance Arg-Pro-Lys-Pro-(CH2)11CH3 [SP1-4C12] was synthesized by forming a peptide bond between Arg-Pro-Lys-Pro, the N-terminal sequence of substance P…”
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Cutaneous responses to vasoactive intestinal polypeptide in chronic idiopathic urticaria by Smith, C H, Atkinson, B, Morris, R W, Hayes, N, Foreman, J C, Lee, T H

“…Cutaneous wheal and flare responses to increasing concentrations of calcitonin gene-related peptide, substance P, neurokinin A, vasoactive intestinal…”
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