Search Results - "Ford Pulido, Julia M"
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Novel series of pyrrolotriazine analogs as highly potent pan-Aurora kinase inhibitors
Published in Bioorganic & medicinal chemistry letters (15-09-2011)“…The synthesis and SAR for a novel series of pyrrolotriazines as pan-Aurora kinase inhibitors are described. The synthesis and SAR for a novel series of…”
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Discovery of Highly Potent and Selective Pan-Aurora Kinase Inhibitors with Enhanced in Vivo Antitumor Therapeutic Index
Published in Journal of medicinal chemistry (12-04-2012)“…Serine/threonine protein kinases Aurora A, B, and C play essential roles in cell mitosis and cytokinesis. Currently a number of Aurora kinase inhibitors with…”
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Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases
Published in ACS medicinal chemistry letters (13-12-2012)“…A series of potent, selective platelet-derived growth factor receptor-family kinase inhibitors was optimized starting from a globally selective lead molecule 4…”
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