Search Results - "Ford, R.A"

Correlation of structural class with no-observed-effect levels: A proposal for establishing a threshold of concern by Munro, I.C., Ford, R.A., Kennepohl, E., Sprenger, J.G.

“…The relationship between chemical structure and toxicity was explored through the compilation of a large reference database consisting of over 600 chemical…”
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Analysis of lead oxide (PbO) layers for direct conversion X-ray detection by Simon, M., Ford, R.A., Franklin, A.R., Grabowski, S.P., Menser, B., Much, G., Nascetti, A., Overdick, M., Powell, M.J., Wiechert, D.U.

“…Lead oxide (PbO) is a candidate direct conversion material for medical X-ray applications. We produced various samples and detectors with thick PbO layers…”
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An evaluation of musk xylene in a battery of genotoxicity tests by Api, A.M., Ford, R.A., San, R.H.C.

“…Musk xylene (CAS no. 81-15-2), a synthetic musk fragrance ingredient, was evaluated in a battery of short-term genotoxicity tests that included the mouse…”
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Safety evaluation of benzophenone by Burdock, G A, Pence, D H, Ford, R A

“…Benzophenone (FEMA No. 2134; CAS No. 119-61-9) was administered in the diet to rats at target dose levels of 20 mg/kg body weight/day for 90 days and 100 or…”
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Safety evaluation of dibenzyl ether by Burdock, G A, Ford, R A

“…Dibenzyl ether (FEMA No. 2371, CAS No. 103-50-4) was given in the diet to rats at a rate of 62, 196 or 620 mg/kg/day for 91 consecutive days. Body weights and…”
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First-order accurate finite difference schemes for boundary vorticity approximations in curvilinear geometries by Siyyam, H.I., Ford, R.A., Hamdan, M.H.

“…In this work we develop first-order accurate, forward finite difference schemes for the first derivative on both a uniform and a non-uniform grid. The schemes…”
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Comparative metabolism and kinetics of coumarin in mice and rats by Born, S.L., Api, A.M., Ford, R.A., Lefever, F.R., Hawkins, D.R.

“…Coumarin, a well recognized rat hepatotoxicant, also causes acute, selective necrosis of terminal bronchiolar Clara cells in the mouse lung. Further, chronic…”
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The FEMA GRAS Assessment of trans-Anethole Used as a Flavouring Substance by Newberne, P, Smith, R.L, Doull, J, Goodman, J.I, Munro, I.C, Portoghese, P.S, Wagner, B.M, Weil, C.S, Woods, L.A, Adams, T.B, Lucas, C.D, Ford, R.A

“…This publication is the fourth in a series of safety evaluations performed by the Expert Panel of the Flavour and Extract Manufacturers’ Association (FEMA). In…”
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Simulation of sedimentation of bidisperse suspensions by Tory, E.M., Ford, R.A.

“…The batch sedimentation behaviour of monodisperse suspensions can be predicted from the flux plot, but this approach is unavailable for polydisperse…”
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Influence of dose and sex on the disposition and hepatic effects of cinnamyl anthranilate in the B6C3F1 mouse by Caldwell, J, Anthony, A, Cotgreave, I A, Sangster, S A, Sutton, J D, Bernard, B K, Ford, R A

“…Cinnamyl anthranilate is a synthetic food flavouring and fragrance agent, formerly used at very low levels. There is currently some concern over the potential…”
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Environmental risk assessment of musk ketone and musk xylene in the Netherlands in accordance with the EU-TGD by Tas, J.W., Balk, F., Ford, R.A., van de Plassche, E.J.

“…An environmental risk assessment has been carried out for musk ketone and musk xylene according to the EU Technical Guidance Document for Environmental Risk…”
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Computational complexities and streamfunction coordinates by Awartani, M.M., Ford, R.A., Hamdan, M.H.

“…In this work we consider some of the computational aspects of viscous fluid flow through two-dimensional curvilinear domains. Associated with the use of the…”
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The in vivo dermal absorption and metabolism of [4- 14C]coumarin by rats and by human volunteers under simulated conditions of use in fragrances by Ford, R.A, Hawkins, D.R, Mayo, B.C, Api, A.M

“…The disposition and metabolic fate of [4- 14C]coumarin in a 70% aqueous ethanol solution was studied in male Lister Hooded rats after occluded dermal…”
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The FEMA GRAS Assessment of Lactones Used as Flavour Ingredients by Adams, T.B., Greer, D.B., Doull, J., Munro, I.C., Newberne, P., Portoghese, P.S., Smith, R.L., Wagner, B.M., Weil, C.S., Woods, L.A., Ford, R.A.

“…This summary presents the key scientific data relevant to the safety evaluation of 44 lactones used as flavour ingredients. Lactones are cyclic esters which…”
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Thermo-ductile composites: new materials for 21st century manufacturing—micro-perforation symmetry by Ford, R.A.

“…New thermo-ductile composite materials with highly aligned discontinuous fibre reinforcement are being developed for the manufacture of light weight structural…”
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Thermo-ductile composites: new materials for 21st Century manufacturing — micro-perforated thermoplastic composites by Ford, R.A

“…Affordable lightweight structures will acquire increasing importance in the 21st Century as improved performance and energy saving become mandatory…”
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The systemic exposure to the polycyclic musks, AHTN and HHCB, under conditions of use as fragrance ingredients: evidence of lack of complete absorption from a skin reservoir by Ford, R.A., Hawkins, D.R., Schwarzenbach, R., Api, A.M.

“…7-Acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene (AHTN) and 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-γ-2-benzopyran (HHCB) are two…”
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Coupled parallel flow through composite porous layers by Ford, R.A., Hamdan, M.H.

“…In this work, we consider fluid flow through composite porous layers. The flow through the layers is either governed by the same flow model with different…”
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Evaluation of the dermal subchronic toxicity of diphenyl ether in the rat by Api, A.M, Ford, R.A

“…Diphenyl ether (DPE) was investigated to determine the dermal absorption parameters and subchronic toxicity of this fragrance ingredient. For the absorption,…”
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Dermal absorption and disposition of musk ambrette, musk ketone and musk xylene in rats by Hawkins, D.R, Ford, R.A

“…Dermal doses of carbon-14 labelled musk ambrette (MA), musk ketone (MK) or musk xylene (MX) to male Sprague–Dawley CD rats were applied at a nominal dose level…”
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