Search Results - "Ford, Nicole R"

Optimizing the Design of Diatom Biosilica-Targeted Fusion Proteins in Biosensor Construction for Bacillus anthracis Detection by Ford, Nicole R, Xiong, Yijia, Hecht, Karen A, Squier, Thomas C, Rorrer, Gregory L, Roesijadi, Guritno

“…In vivo functionalization of diatom biosilica frustules by genetic manipulation requires careful consideration of the overall structure and function of complex…”
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Genomewide Gain-of-Function Genetic Screen Identifies Functionally Active Genes in Mouse Embryonic Stem Cells by Pritsker, Moshe, Ford, Nicole R., Jenq, Harry T., Lemischka, Ihor R.

“…Embryonic stem (ES) cells hold great promise for the future of medicine. To elucidate the molecular mechanisms that control ES cell self-renewal and…”
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Distance-Matched Tagging Sequence Optimizes Live-Cell Protein Labeling by a Biarsenical Fluorescent Reagent AsCy3_E by Hecht, Karen A, Xiong, Yijia, Barrack, Daniel A, Ford, Nicole R, Roesijadi, Guritno, Squier, Thomas C

“…Cell permeable biarsenical fluorescent dyes built around a cyanine scaffold (AsCy3) create the ability to monitor the structural dynamics of tagged proteins in…”
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Dynamic Stabilization of Expressed Proteins in Engineered Diatom Biosilica Matrices by Xiong, Yijia, Ford, Nicole R, Hecht, Karen A, Roesijadi, Guritno, Squier, Thomas C

“…Self-assembly of recombinant proteins within the biosilica of living diatoms represents a means to construct functional materials in a reproducible and…”
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Hydrogel Tethering Enhances Interdomain Stabilization of Single-Chain Antibodies by Xiong, Yijia, Ford, Nicole R, Hecht, Karen A, Roesijadi, Guritno, Squier, Thomas C

“…Here, we identify the importance of molecular crowding agents in the functional stabilization of scFv antibodies. Antibodies were tethered through an…”
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Inflammatory signals direct expression of human IL12RB1 into multiple distinct isoforms by Ford, Nicole R, Miller, Halli E, Reeme, Allison E, Waukau, Jill, Bengtson, Christine, Routes, John M, Robinson, Richard T

“…IL12RB1 is essential for human resistance to multiple intracellular pathogens, including Mycobacterium tuberculosis. In its absence, the proinflammatory…”
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Antigen Binding and Site-Directed Labeling of Biosilica-Immobilized Fusion Proteins Expressed in Diatoms by Ford, Nicole R, Hecht, Karen A, Hu, DeHong, Orr, Galya, Xiong, Yijia, Squier, Thomas C, Rorrer, Gregory L, Roesijadi, Guritno

“…The diatom Thalassiosira pseudonana was genetically modified to express biosilica-targeted fusion proteins comprising either enhanced green fluorescent protein…”
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Dispensability of nanos mRNA localization for abdominal patterning but not for germ cell development by Gavis, Elizabeth R., Chatterjee, Seema, Ford, Nicole R., Wolff, Lisa J.

“…The development of a functional germline is essential for species propagation. The nanos ( nos) gene plays an evolutionarily conserved role in germline…”
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Dynamic Stabilization of Expressed Proteins in Engineered Diatom Biosilica by Xiong, Yijia, Ford, Nicole R., Hecht, Karen A., Roesijadi, Guritno, Squier, Thomas C.

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In Vivo Point Mutation Repair: The Sickle Cell Allele as a Demonstration Case by d, Nicole R

“…Disease phenotypes that can be traced to point mutations are amenable to gene therapy by direct repair of the disease-causing allele on the chromosome. Here,…”
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In Vivo Point Mutation Repair: The Sickle Cell Allele as a Demonstration Case by Ford, Nicole R

“…Disease phenotypes that can be traced to point mutations are amenable to gene therapy by direct repair of the disease-causing allele on the chromosome. Here,…”
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