Search Results - "Ford, Ian"

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies by Kaptoge, Stephen, Butterworth, Adam S, Willeit, Peter, Bolton, Thomas, Paige, Ellie, Paul, Dirk S, Bell, Steven, Astle, William, Verschuren, W M Monique, Sato, Shinichi, Njølstad, Inger, Salomaa, Veikko, Yeap, Bu B, Melander, Olle, Marmot, Michael, Dahm, Christina C, Dale, Caroline E, van der Schouw, Yvonne T, Simons, Leon A, Schoufour, Josje D, Key, Timothy J, Moreno-Iribas, Conchi, Davidson, Karina W, Taylor, James O, Wallace, Robert B, Tumino, Rosario, Linneberg, Allan, Panico, Salvatore, Nietert, Paul J, Kromhout, Daan, Kiechl, Stefan, Palli, Domenico, Huerta, José M, Karakatsani, Anna, Kühn, Tilman, Grobbee, Diederick E, Kauhanen, Jussi, Wennberg, Maria, Cushman, Mary, Cooper, Jackie A, Rodriguez, Carlos J, Shaw, Jonathan E, Voortman, Trudy, Dallongeville, Jean, Brunner, Eric J, Lazo, Mariana, Leon, David A, Smith, George Davey, Peto, Richard, Jackson, Rod, Banks, Emily, Butterworth, Adam, Warnakula, Samantha, Paige, Ellie, Bell, Steven, Astle, William, Sato, Shinichi, Veikko, Salomaa, Flecther, Astrid, Melander, Olle, Kuller, Lewis H, Koenig, Wolfgang, Casiglia, Edoardo, Arndt, Volker, Völzke, Henry, Dahm, Christina C, Dale, Caroline E, Bergmann, Manuela, Crespo, Carlos, Kaaks, Rudolf, Simons, Leon A, Lagiou, Pagona, Key, Timothy J, Rodriguez, Beatriz, Moreno-Iribas, Conchi, Davidson, Karina W, Quiros, J. Ramon, Skeie, Guri, Salomaa, Veikko, Strandberg, Timo, Nietert, Paul J, Salamanca-Fernandez, Elena, Krumholz, Harlan M, Price, Jackie, Travis, Ruth C, Kühn, Tilman, Barrett-Connor, Elizabeth, van Schoor, Natasja, Boeing, Heiner, Overvad, Kim, Kauhanen, Jussi, Forouhi, Nita, Wennberg, Maria, Brenner, Hermann, Assmann, Gerd, Trevisan, Maurizio, Gillumn, Richard F, Thompson, Simon, Ferrari, Pietro, Davey Smith, George

“…Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk…”
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High-Sensitivity Cardiac Troponin, Statin Therapy, and Risk of Coronary Heart Disease by Ford, Ian, PhD, Shah, Anoop S.V., MD, Zhang, Ruiqi, MSc, McAllister, David A., MD, Strachan, Fiona E., PhD, Caslake, Muriel, PhD, Newby, David E., MD, Packard, Chris J., DSc, Mills, Nicholas L., MD

“…Abstract Background Cardiac troponin is an independent predictor of cardiovascular mortality in individuals without symptoms or signs of cardiovascular…”
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Ivabradine in Stable Coronary Artery Disease without Clinical Heart Failure by Fox, Kim, Ford, Ian, Steg, Philippe Gabriel, Tardif, Jean-Claude, Tendera, Michal, Ferrari, Roberto

“…In this trial, over 19,000 patients with stable coronary artery disease were assigned to ivabradine (adjusted to achieve a target heart rate) or placebo. At 27…”
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Prenucleation Cluster Pathway is Inconsistent with CaCO 3 Kinetics by Darkins, Robert, Duffy, Dorothy M, Ford, Ian J

“…It has been debated whether CaCO nucleates classically with the attainment of a critical cluster size or nonclassically with the restructuring of a…”
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Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study by Vidal-Petiot, Emmanuelle, MD, Ford, Ian, Prof, Greenlaw, Nicola, MSc, Ferrari, Roberto, Prof, Fox, Kim M, Prof, Tardif, Jean-Claude, Prof, Tendera, Michal, Prof, Tavazzi, Luigi, Prof, Bhatt, Deepak L, Prof, Steg, Philippe Gabriel, Prof

“…Summary Background The optimum blood pressure target in hypertension remains debated, especially in coronary artery disease, given concerns for reduced…”
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Nonequilibrium thermodynamics of stochastic systems with odd and even variables by Spinney, Richard E, Ford, Ian J

“…The total entropy production of stochastic systems can be divided into three quantities. The first corresponds to the excess heat, while the second two…”
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Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial by Williams, Bryan, Prof, MacDonald, Thomas M, Prof, Morant, Steve, PhD, Webb, David J, Prof, Sever, Peter, Prof, McInnes, Gordon, Prof, Ford, Ian, Prof, Cruickshank, J Kennedy, Prof, Caulfield, Mark J, Prof, Salsbury, Jackie, Prof, Mackenzie, Isla, FRCP, Padmanabhan, Sandosh, FRCP, Brown, Morris J, Prof

“…Summary Background Optimal drug treatment for patients with resistant hypertension is undefined. We aimed to test the hypotheses that resistant hypertension is…”
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High-Sensitivity Cardiac Troponin Concentration and Risk of First-Ever Cardiovascular Outcomes in 154,052 Participants by Willeit, Peter, Welsh, Paul, Evans, Jonathan D.W., Tschiderer, Lena, Boachie, Charles, Jukema, J. Wouter, Ford, Ian, Trompet, Stella, Stott, David J., Kearney, Patricia M., Mooijaart, Simon P., Kiechl, Stefan, Di Angelantonio, Emanuele, Sattar, Naveed

“…High-sensitivity assays can quantify cardiac troponins I and T (hs-cTnI, hs-cTnT) in individuals with no clinically manifest myocardial injury. The goal of…”
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Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial by Curzen, Nick, Nicholas, Zoe, Stuart, Beth, Wilding, Sam, Hill, Kayleigh, Shambrook, James, Eminton, Zina, Ball, Darran, Barrett, Camilla, Johnson, Lucy, Nuttall, Jacqui, Fox, Kim, Connolly, Derek, O’Kane, Peter, Hobson, Alex, Chauhan, Anoop, Uren, Neal, Mccann, Gerry, Berry, Colin, Carter, Justin, Roobottom, Carl, Mamas, Mamas, Rajani, Ronak, Ford, Ian, Douglas, Pamela, Hlatky, Mark

“…Abstract Aims  Fractional flow reserve (FFRCT) using computed tomography coronary angiography (CTCA) determines both the presence of coronary artery disease…”
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Alteplase versus tenecteplase for thrombolysis after ischaemic stroke (ATTEST): a phase 2, randomised, open-label, blinded endpoint study by Huang, Xuya, MRCP, Cheripelli, Bharath Kumar, MRCP, Lloyd, Suzanne M, MSc, Kalladka, Dheeraj, MRCP, Moreton, Fiona Catherine, MRCP, Siddiqui, Aslam, FRCR, Ford, Ian, PhD, Muir, Keith W, Prof

“…Summary Background In most countries, alteplase given within 4·5 h of onset is the only approved medical treatment for acute ischaemic stroke. The newer…”
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Electronic health records to facilitate clinical research by Cowie, Martin R., Blomster, Juuso I., Curtis, Lesley H., Duclaux, Sylvie, Ford, Ian, Fritz, Fleur, Goldman, Samantha, Janmohamed, Salim, Kreuzer, Jörg, Leenay, Mark, Michel, Alexander, Ong, Seleen, Pell, Jill P., Southworth, Mary Ross, Stough, Wendy Gattis, Thoenes, Martin, Zannad, Faiez, Zalewski, Andrew

“…Electronic health records (EHRs) provide opportunities to enhance patient care, embed performance measures in clinical practice, and facilitate clinical…”
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Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study by Swedberg, Karl, Prof, Komajda, Michel, Prof, Böhm, Michael, Prof, Borer, Jeffrey S, Prof, Ford, Ian, Prof, Dubost-Brama, Ariane, MD, Lerebours, Guy, MD, Tavazzi, Luigi, Prof

“…Summary Background Chronic heart failure is associated with high mortality and morbidity. Raised resting heart rate is a risk factor for adverse outcomes. We…”
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Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial by Böhm, Michael, Prof, Swedberg, Karl, Prof, Komajda, Michel, Prof, Borer, Jeffrey S, Prof, Ford, Ian, Prof, Dubost-Brama, Ariane, MD, Lerebours, Guy, MD, Tavazzi, Luigi, Prof

“…Summary Background Raised resting heart rate is a marker of cardiovascular risk. We postulated that heart rate is also a risk factor for cardiovascular events…”
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Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study by Brouilette, Scott W, PhD, Moore, Jasbir S, MSc, McMahon, Alex D, PhD, Thompson, John R, Prof, Ford, Ian, Prof, Shepherd, James, Prof, Packard, Chris J, Prof, Samani, Nilesh J, Prof

“…Summary Background Inter-individual differences in biological ageing could affect susceptibility to coronary heart disease. Our aim was to determine whether…”
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Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies by Davis, Luke K, Ford, Ian J, Hoogenboom, Bart W

“…The rapid (<1 ms) transport of biological material to and from the cell nucleus is regulated by the nuclear pore complex (NPC). At the core of the NPC is a…”
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Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial by Fox, Kim, Prof, Ford, Ian, Prof, Steg, P Gabriel, Prof, Tendera, Michal, Prof, Robertson, Michele, BSc, Ferrari, Roberto, Prof

“…Summary Background The BEAUTIFUL study assessed the morbidity and mortality benefits of the heart rate-lowering agent ivabradine. The placebo arm of the…”
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Long-term outcomes of chronic coronary syndrome worldwide: insights from the international CLARIFY registry by Sorbets, Emmanuel, Fox, Kim M, Elbez, Yedid, Danchin, Nicolas, Dorian, Paul, Ferrari, Roberto, Ford, Ian, Greenlaw, Nicola, Kalra, Paul R, Parma, Zofia, Shalnova, Svetlana, Tardif, Jean-Claude, Tendera, Michal, Zamorano, José Luis, Vidal-Petiot, Emmanuelle, Steg, Philippe Gabriel

“…Abstract Aims Over the last decades, the profile of chronic coronary syndrome has changed substantially. We aimed to determine characteristics and management…”
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International Observational Analysis of Evolution and Outcomes of Chronic Stable Angina: The Multinational CLARIFY Study by Mesnier, Jules, Ducrocq, Gregory, Danchin, Nicolas, Ferrari, Roberto, Ford, Ian, Tardif, Jean-Claude, Tendera, Michal, Fox, Kim M, Steg, Philippe Gabriel

“…Although angina is common in patients with stable coronary artery disease, limited data are available on its prevalence, natural evolution, and outcomes in the…”
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Intravenous Iron Dosing and Infection Risk in Patients on Hemodialysis: A Prespecified Secondary Analysis of the PIVOTAL Trial by Macdougall, Iain C, Bhandari, Sunil, White, Claire, Anker, Stefan D, Farrington, Kenneth, Kalra, Philip A, Mark, Patrick B, McMurray, John J V, Reid, Chante, Robertson, Michele, Tomson, Charles R V, Wheeler, David C, Winearls, Christopher G, Ford, Ian

“…Experimental and observational studies have raised concerns that giving intravenous (IV) iron to patients, such as individuals receiving maintenance…”
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Measures of thermodynamic irreversibility in deterministic and stochastic dynamics by Ford, Ian J

“…It is generally observed that if a dynamical system is sufficiently complex, then as time progresses it will share out energy and other properties amongst its…”
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