Search Results - "Ford, Clifford E"

The application of olivine geothermometry to infer crystallization temperatures of parental liquids: Implications for the temperature of MORB magmas by Falloon, Trevor J., Danyushevsky, Leonid V., Ariskin, Alexei, Green, David H., Ford, Clifford E.

“…We have performed a detailed evaluation of three olivine geothermometers for anhydrous systems representing three different approaches to modelling…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P1 Lactam Moieties as l-Glutamine Replacements by Dragovich, Peter S, Prins, Thomas J, Zhou, Ru, Webber, Stephen E, Marakovits, Joseph T, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Lee, Caroline A, Ford, Clifford E, Burke, Benjamin J, Rejto, Paul A, Hendrickson, Thomas F, Tuntland, Tove, Brown, Edward L, Meador, James W, Ferre, Rose Ann, Harr, James E. V, Kosa, Maha B, Worland, Stephen T

“…The structure-based design, chemical synthesis, and biological evaluation of various human rhinovirus (HRV) 3C protease (3CP) inhibitors which incorporate P1…”
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Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease by Webber, Stephen E., Tikhe, Jayashree, Worland, Stephen T., Fuhrman, Shella A., Hendrickson, Thomas F., Matthews, David A., Love, Robert A., Patick, Amy K., Meador, James W., Ferre, Rose Ann, Brown, Edward L., DeLisle, Dorothy M., Ford, Clifford E., Binford, Susan L.

“…The design, synthesis, and biological evaluation of reversible, nonpeptidic inhibitors of human rhinovirus (HRV) 3C protease (3CP) are reported. A novel series…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies by Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Lee, Caroline A, Reich, Siegfried H, Prins, Thomas J, Marakovits, Joseph T, Littlefield, Ethel S, Zhou, Ru, Tikhe, Jayashree, Ford, Clifford E, Wallace, Michael B, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, Harr, James E. V, DeLisle, Dorothy M, Worland, Stephen T

“…The structure-based design, chemical synthesis, and biological evaluation of peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are described…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies by Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Reich, Siegfried H, Marakovits, Joseph T, Prins, Thomas J, Zhou, Ru, Tikhe, Jayashree, Littlefield, Ethel S, Bleckman, Ted M, Wallace, Michael B, Little, Thomas L, Ford, Clifford E, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, DeLisle, Dorothy M, Worland, Stephen T

“…The structure-based design, chemical synthesis, and biological evaluation of various peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are…”
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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements by Webber, Stephen E, Okano, Koji, Little, Thomas L, Reich, Siegfried H, Xin, Yue, Fuhrman, Shella A, Matthews, David A, Love, Robert A, Hendrickson, Thomas F, Patick, Amy K, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Ford, Clifford E, Binford, Susan L, Worland, Stephen T

“…The investigation of tripeptide aldehydes as reversible covalent inhibitors of human rhinovirus (HRV) 3C protease (3CP) is reported. Molecular models based on…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 3. Structure−Activity Studies of Ketomethylene-Containing Peptidomimetics by Dragovich, Peter S, Prins, Thomas J, Zhou, Ru, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Ford, Clifford E, Meador, James W, Ferre, Rose Ann, Worland, Stephen T

“…The structure-based design, chemical synthesis, and biological evaluation of various ketomethylene-containing human rhinovirus (HRV) 3C protease (3CP)…”
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Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease:  Structure-Based Design, Synthesis, and Biological Evaluation by Reich, Siegfried H, Johnson, Theodore, Wallace, Michael B, Kephart, Susan E, Fuhrman, Shella A, Worland, Stephen T, Matthews, David A, Hendrickson, Thomas F, Chan, Fora, Meador, James, Ferre, Rose Ann, Brown, Edward L, DeLisle, Dorothy M, Patick, Amy K, Binford, Susan L, Ford, Clifford E

“…A series of nonpeptide benzamide-containing inhibitors of human rhinovirus (HRV) 3C protease was identified using structure-based design. The design,…”
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Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors by Webber, Stephen E., Marakovits, Joseph T., Dragovich, Peter S., Prins, Thomas J., Zhou, Ru, Fuhrman, Shella A., Patick, Amy K., Matthews, David A., Lee, Caroline A., Srinivasan, Babu, Moran, Terry, Ford, Clifford E., Brothers, Mary A., Harr, James E.V., Meador, James W., Ferre, Rose Ann, Worland, Stephen T.

“…Novel tripeptidyl C-terminal Michael acceptors with an ester replacement of the P 2–P 3 amide bond were investigated as irreversible inhibitors of the human…”
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Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids by Dragovich, Peter S, Webber, Stephen E, Prins, Thomas J, Zhou, Ru, Marakovits, Joseph T, Tikhe, Jayashree G, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Ford, Clifford E, Brown, Edward L, Binford, Susan L, Meador, James W, Ferre, Rose Ann, Worland, Stephen T

“…Tripeptide-derived molecules incorporating N-methyl amino acid residues and C-terminal Michael acceptor moieties were evaluated as irreversible inhibitors of…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P 1 Lactam Moieties as l -Glutamine Replacements by Dragovich, Peter S., Prins, Thomas J., Zhou, Ru, Webber, Stephen E., Marakovits, Joseph T., Fuhrman, Shella A., Patick, Amy K., Matthews, David A., Lee, Caroline A., Ford, Clifford E., Burke, Benjamin J., Rejto, Paul A., Hendrickson, Thomas F., Tuntland, Tove, Brown, Edward L., Meador, James W., Ferre, Rose Ann, Harr, James E. V., Kosa, Maha B., Worland, Stephen T.

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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements by Webber, Stephen E., Okano, Koji, Little, Thomas L., Reich, Siegfried H., Xin, Yue, Fuhrman, Shella A., Matthews, David A., Love, Robert A., Hendrickson, Thomas F., Patick, Amy K., Meador, James W., Ferre, Rose Ann, Brown, Edward L., Ford, Clifford E., Binford, Susan L., Worland, Stephen T.

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Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides by Dragovich, Peter S., Zhou, Ru, Skalitzky, Donald J., Fuhrman, Shella A., Patick, Amy K., Ford, Clifford E., Meador, James W., Worland, Stephen T.

“…The optimization of a series of irreversible human rhinovirus (HRV) 3C protease (3CP) inhibitors is described. These inhibitors are comprised of an l-Leu-…”
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Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors by DRAGOVICH, P. S, RU ZHOU, MEADOR, J. W, PATICK, A. K, FORD, C. E, BROTHERS, M. A, BINFORD, S. L, MATTHEWS, D. A, FERRE, R. A, WORLAND, S. T, WEBBER, S. E, PRINS, T. J, KWOK, A. K, OKANO, K, FUHRMAN, S. A, ZALMAN, L. S, MALDONADO, F. C, BROWN, E. L

“…Tripeptide-derived molecules incorporating C-terminal ketone electrophiles were evaluated as reversible inhibitors of the cysteine-containing human rhinovirus…”
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Phase relations in the Fe-Zn-S system to 5 kbars and temperatures between 325° and 150°C by Lusk, John, Scott, Steven D, Ford, Clifford E

“…Sphalerite, pyrite, and pyrrhotite were recrystallized together in a saturated ammonium iodide solution at 150° to 325°C and 0.4 to 5.1 kbars. The data were…”
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Myocardial β-adrenergic receptor expression and signal transduction after chronic volume-overload hypertrophy and circulatory congestion by KIRK HAMMOND, H, ROTH, D. A, INSEL, P. A, FORD, C. E, WHITE, F. C, MAISEL, A. S, ZIEGLER, M. G, BLOOR, C. M

“…The volume-overload, high-output state induced by aortocaval fistula is unique because it is not generally associated with marked abnormalities of contractile…”
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Phase relations in the Fe-Zn-S system to 5 kbars and temperatures between 325 degrees and 150 degrees C by Lusk, John, Scott, Steven D., Ford, Clifford E.

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Myocardial adrenergic denervation supersensitivity depends on a postreceptor mechanism not linked with increased cAMP production by HAMOND, H. K, ROTH, D. A, FORD, C. E, STAMNAS, G. W, ZIEGLER, M. G, ENNIS, C

“…Two major hypotheses have been proposed to explain catecholamine supersensitivity after myocardial denervation, but neither sufficiently explains certain…”
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