Search Results - "Ford, Caroline"

Sensing extracellular matrix: An update on discoidin domain receptor function by Vogel, Wolfgang F., Abdulhussein, Rahim, Ford, Caroline E.

“…Discoidin Domain Receptors (DDRs) have recently emerged as non-integrin-type receptors for collagen. The two mammalian gene products Discoidin Domain Receptor…”
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Endogenous Cell-free DNA in Fetal Bovine Serum Introduces Artifacts to in Vitro cell-free DNA Models by Werner, Bonnita, Warton, Kristina, Ford, Caroline E

“…Cell-free DNA (cfDNA) is of growing clinical and research significance. In vitro cfDNA models are a useful tool in cfDNA research; however, artifacts in these…”
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Sex Bias in Cohorts Included in Sports Medicine Research by Hagstrom, Amanda D., Yuwono, Nicole, Warton, Kristina, Ford, Caroline E.

“…Due to its origin from dying cells, cfDNA in the bloodstream is strongly linked to inflammation. [...]its fluctuation in response to exercise is of significant…”
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Recovery Efficiency of Cell-Free DNA After Bisulfite Conversion by Fisher, Teagan, Ford, Caroline E, Warton, Kristina

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A comparative analysis of 2D and 3D experimental data for the identification of the parameters of computational models by Cortesi, Marilisa, Liu, Dongli, Yee, Christine, Marsh, Deborah J., Ford, Caroline E.

“…Computational models are becoming an increasingly valuable tool in biomedical research. Their accuracy and effectiveness, however, rely on the identification…”
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Beyond 2D cell cultures: how 3D models are changing the in vitro study of ovarian cancer and how to make the most of them by Cortesi, Marilisa, Warton, Kristina, Ford, Caroline E

“…3D cell cultures are a fundamental tool in ovarian cancer research that can enable more effective study of the main features of this lethal disease, including…”
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The Wnt gatekeeper SFRP4 modulates EMT, cell migration and downstream Wnt signalling in serous ovarian cancer cells by Ford, Caroline E, Jary, Eve, Ma, Sean Si Qian, Nixdorf, Sheri, Heinzelmann-Schwarz, Viola A, Ward, Robyn L

“…Aberrant Wnt signalling is implicated in numerous human cancers, and understanding the effects of modulation of pathway members may lead to the development of…”
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The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer by Loh, Yan Ni, Hedditch, Ellen L, Baker, Laura A, Jary, Eve, Ward, Robyn L, Ford, Caroline E

“…Acquired resistance to Tamoxifen remains a critical problem in breast cancer patient treatment, yet the underlying causes of resistance have not been fully…”
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Author Correction: A comparative analysis of 2D and 3D experimental data for the identification of the parameters of computational models by Cortesi, Marilisa, Liu, Dongli, Yee, Christine, Marsh, Deborah J., Ford, Caroline E.

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Transcending Blood-Opportunities for Alternate Liquid Biopsies in Oncology by Werner, Bonnita, Warton, Kristina, Ford, Caroline E

“…Cell-free DNA (cfDNA) is a useful molecular biomarker in oncology research and treatment, but while research into its properties in blood has flourished, there…”
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Circulating cell-free DNA is elevated in postmenopausal compared with pre- and perimenopausal women by Fisher, Teagan, Powell, Elyse, Yuwono, Nicole L, Ford, Caroline E, Warton, Kristina

“…With the rising use of circulating cell-free DNA (cirDNA) liquid biopsies for disease screening, it is important to understand biological differences that may…”
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Dual-locus DNA metabarcoding reveals southern hairy-nosed wombats (Lasiorhinus latifrons Owen) have a summer diet dominated by toxic invasive plants by Camp, Amanda, Croxford, Adam E, Ford, Caroline S, Baumann, Ute, Clements, Peter R, Hiendleder, Stefan, Woolford, Lucy, Netzel, Gabrielle, Boardman, Wayne S J, Fletcher, Mary T, Wilkinson, Mike J

“…Habitat degradation and summer droughts severely restrict feeding options for the endangered southern hairy-nosed wombat (SHNW; Lasiorhinus latifrons). We…”
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The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis by Ford, Caroline E., Qian Ma, Sean Si, Quadir, Ashfaque, Ward, Robyn L.

“…The Wnt signaling pathway is involved in the development and progression of many human cancers, yet attempts to target the pathway therapeutically have been…”
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The untapped potential of ascites in ovarian cancer research and treatment by Ford, Caroline Elizabeth, Werner, Bonnita, Hacker, Neville Frederick, Warton, Kristina

“…The build-up of fluid in the peritoneal cavity—ascites—is a hallmark of ovarian cancer, the most lethal of all gynaecological malignancies. This remarkable…”
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Cell‐free DNA from ascites identifies clinically relevant variants and tumour evolution in patients with advanced ovarian cancer by Werner, Bonnita, Powell, Elyse, Duggan, Jennifer, Cortesi, Marilisa, Lee, Yeh Chen, Arora, Vivek, Athavale, Ramanand, Dean, Michael, Warton, Kristina, Ford, Caroline E.

“…The emergence of targeted therapies has transformed ovarian cancer treatment. However, biomarker profiling for precision medicine is limited by access to…”
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ROR2 Is Epigenetically Regulated in Endometrial Cancer by Liu, Dongli, Enriquez, Luis, Ford, Caroline E

“…The Wnt signalling receptor ROR2 has been identified as a possible therapeutic target in numerous cancers; however, its exact role remains unclear. The aim of…”
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Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight by Werner, Bonnita, Yuwono, Nicole Laurencia, Henry, Claire, Gunther, Kate, Rapkins, Robert William, Ford, Caroline Elizabeth, Warton, Kristina

“…Methylation patterns in circulating cell-free DNA are potential biomarkers for cancer and other pathologies. Currently, bisulfite treatment underpins most DNA…”
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Replacing Sanger with Next Generation Sequencing to improve coverage and quality of reference DNA barcodes for plants by Wilkinson, Mike J., Szabo, Claudia, Ford, Caroline S., Yarom, Yuval, Croxford, Adam E., Camp, Amanda, Gooding, Paul

“…We estimate the global BOLD Systems database holds core DNA barcodes ( rbcL  +  matK ) for about 15% of land plant species and that comprehensive species…”
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Pan-Tissue and -Cancer Analysis of ROR1 and ROR2 Transcript Variants Identify Novel Functional Significance for an Alternative Splice Variant of ROR1 by John, Miya, Ford, Caroline E

“…ROR1/2 are putative druggable targets increasing in significance in translational oncology. Expression of ROR1/2 mRNA and transcript variants has not been…”
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Accurate Identification of Cancer Cells in Complex Pre‐Clinical Models Using a Deep‐Learning Neural Network: A Transfection‐Free Approach by Cortesi, Marilisa, Liu, Dongli, Powell, Elyse, Barlow, Ellen, Warton, Kristina, Ford, Caroline E.

“…3D co‐cultures are key tools for in vitro biomedical research as they recapitulate more closely the in vivo environment while allowing a tighter control on the…”
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