Search Results - "Foran, Patrick G."

The janus faces of botulinum neurotoxin: Sensational medicine and deadly biological weapon by Osborne, Shona L., Latham, Catherine F., Wen, Peter J., Cavaignac, Sonia, Fanning, Jonathon, Foran, Patrick G., Meunier, Frederic A.

“…The botulinum neurotoxins are the most dangerous toxins known (BoNTs serotypes A–G) and induce profound flaccid neuromuscular paralysis by blocking…”
Get full text

Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A. Basis for distinct durations of inhibition of exocytosis in central neurons by Foran, Patrick G, Mohammed, Nadiem, Lisk, Godfrey O, Nagwaney, Sharuna, Lawrence, Gary W, Johnson, Eric, Smith, Leonard, Aoki, K Roger, Dolly, J Oliver

“…Seven types (A-G) of botulinum neurotoxin (BoNT) target peripheral cholinergic neurons where they selectively proteolyze SNAP-25 (BoNT/A, BoNT/C1, and BoNT/E),…”
Get full text

Glial heterogeneity in expression of the inwardly rectifying K+ channel, Kir4.1, in adult rat CNS by Poopalasundaram, Subathra, Knott, Christine, Shamotienko, Oleg G., Foran, Patrick G., Dolly, J. Oliver, Ghiani, Cristina A., Gallo, Vittorio, Wilkin, Graham P.

“…Previous electrophysiological evidence has indicated that astrocytes and oligodendrocytes express inwardly rectifying K+ channels both in vitro and in vivo…”
Get full text

Getting muscles moving again after botulinum toxin: novel therapeutic challenges by Foran, Patrick G., Davletov, Bazbek, Meunier, Frederic A.

“…The use of botulinum neurotoxins for the treatment of muscle hyperactivity and spasticity disorders has been remarkably successful, owing to the abilities of…”
Get full text

Evaluation of the Therapeutic Usefulness of Botulinum Neurotoxin B, C1, E, and F Compared with the Long Lasting Type A by Foran, Patrick G., Mohammed, Nadiem, Lisk, Godfrey O., Nagwaney, Sharuna, Lawrence, Gary W., Johnson, Eric, Smith, Leonard, Aoki, K. Roger, Dolly, J. Oliver

“…Seven types (A–G) of botulinum neurotoxin (BoNT) target peripheral cholinergic neurons where they selectively proteolyze SNAP-25 (BoNT/A, BoNT/C1, and BoNT/E),…”
Get full text

Rescue of Exocytosis in Botulinum Toxin A-poisoned Chromaffin Cells by Expression of Cleavage-resistant SNAP-25 by Gregory A. O'Sullivan, Nadiem Mohammed, Patrick G. Foran, Gary W. Lawrence, J. Oliver Dolly

“…Botulinum neurotoxin (BoNT) types A and B selectively block exocytosis by cleavage of SNAP-25 and synaptobrevin, respectively; in humans, many months are…”
Get full text

Rescue of exocytosis in botulinum toxin A-poisoned chromaffin cells by expression of cleavage-resistant SNAP-25. Identification of the minimal essential C-terminal residues by O'Sullivan, G A, Mohammed, N, Foran, P G, Lawrence, G W, Oliver Dolly, J

“…Botulinum neurotoxin (BoNT) types A and B selectively block exocytosis by cleavage of SNAP-25 and synaptobrevin, respectively; in humans, many months are…”
Get full text

Protein Kinase B Stimulates the Translocation of GLUT4 but Not GLUT1 or Transferrin Receptors in 3T3-L1 Adipocytes by a Pathway Involving SNAP-23, Synaptobrevin-2, and/or Cellubrevin by Foran, Patrick G.P., Fletcher, Laura M., Oatey, Paru B., Mohammed, Nadiem, Dolly, J. Oliver, Tavaré, Jeremy M.

“…An interaction of SNAP-23 and syntaxin 4 on the plasma membrane with vesicle-associated synaptobrevin-2 and/or cellubrevin, known as SNAP (soluble…”
Get full text