Search Results - "Forés, Joaquim"

Boosted Regeneration and Reduced Denervated Muscle Atrophy by NeuroHeal in a Pre-clinical Model of Lumbar Root Avulsion with Delayed Reimplantation by Romeo-Guitart, David, Forés, Joaquim, Navarro, Xavier, Casas, Caty

“…The “gold standard” treatment of patients with spinal root injuries consists of delayed surgical reconnection of nerves. The sooner, the better, but problems…”
Get full text

Improved Motor Nerve Regeneration by SIRT1/Hif1a-Mediated Autophagy by Romeo-Guitart, David, Leiva-Rodriguez, Tatiana, Forés, Joaquim, Casas, Caty

“…Complete restoring of functional connectivity between neurons or target tissue after traumatic lesions is still an unmet medical need. Using models of nerve…”
Get full text

Chronic transplantation of olfactory ensheathing cells promotes partial recovery after complete spinal cord transection in the rat by López-Vales, Rubèn, Forés, Joaquim, Navarro, Xavier, Verdú, Enrique

“…The goal of this study was to ascertain whether olfactory ensheathing cells (OECs) were able to promote axonal regeneration and functional recovery when…”
Get full text

Acute and delayed transplantation of olfactory ensheathing cells promote partial recovery after complete transection of the spinal cord by López-Vales, Rubèn, Forés, Joaquim, Verdú, Enrique, Navarro, Xavier

“…The present study was undertaken to determine whether olfactory ensheathing cells (OECs) from the olfactory bulb were capable to promote axonal regeneration…”
Get full text

Acute transplantation of olfactory ensheathing cells or Schwann cells promotes recovery after spinal cord injury in the rat by García-Alías, Guillermo, López-Vales, Rubén, Forés, Joaquim, Navarro, Xavier, Verdú, Enrique

“…We compared the neurological and electrophysiological outcome, glial reactivity, and spared spinal cord connectivity promoted by acute transplantation of…”
Get full text

FK506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat by López-Vales, Rubèn, García-Alías, Guillermo, Forés, Joaquim, Udina, Esther, Gold, Bruce G., Navarro, Xavier, Verdú, Enrique

“…We examined the efficacy of FK506 in reducing tissue damage after spinal cord injury in comparison to methylprednisolone (MP) treatment. Rats were subjected to…”
Get full text

Neuroprotective Drug for Nerve Trauma Revealed Using Artificial Intelligence by Romeo-Guitart, David, Forés, Joaquim, Herrando-Grabulosa, Mireia, Valls, Raquel, Leiva-Rodríguez, Tatiana, Galea, Elena, González-Pérez, Francisco, Navarro, Xavier, Petegnief, Valerie, Bosch, Assumpció, Coma, Mireia, Mas, José Manuel, Casas, Caty

“…Here we used a systems biology approach and artificial intelligence to identify a neuroprotective agent for the treatment of peripheral nerve root avulsion…”
Get full text

Repair of Long Peripheral Nerve Defects in Sheep: A Translational Model for Nerve Regeneration by Contreras, Estefanía, Traserra, Sara, Bolívar, Sara, Forés, Joaquím, Jose-Cunilleras, Eduard, Delgado-Martínez, Ignacio, García, Félix, Udina, Esther, Navarro, Xavier

“…Despite advances in microsurgery, full functional recovery of severe peripheral nerve injuries is not commonly attained. The sheep appears as a good…”
Get full text

Decellularized Graft for Repairing Severe Peripheral Nerve Injuries in Sheep by Contreras, Estefanía, Traserra, Sara, Bolívar, Sara, Nieto-Nicolau, Núria, Jaramillo, Jessica, Forés, Joaquim, Jose-Cunilleras, Eduard, Moll, Xavier, García, Félix, Delgado-Martínez, Ignacio, Fariñas, Oscar, López-Chicón, Patrícia, Vilarrodona, Anna, Udina, Esther, Navarro, Xavier

“…Peripheral nerve injuries resulting in a nerve defect require surgical repair. The gold standard of autograft (AG) has several limitations, and therefore, new…”
Get full text

Effects of ensheathing cells transplanted into photochemically damaged spinal cord by Verdú, Enrique, García-Alías, Guillermo, Forés, Joaquim, Gudiño-Cabrera, Graciela, Muñetón, Vilma C, Nieto-Sampedro, Manuel, Navarro, Xavier

“…Transplantation of olfactory ensheathing cells (OECs) into photochemically damaged rat spinal cord diminished astrocyte reactivity and parenchyma cavitation…”
Get full text

Sigma receptor agonist 2-(4-morpholinethyl)1 phenylcyclohexanecarboxylate (Pre084) increases GDNF and BiP expression and promotes neuroprotection after root avulsion injury by Penas, Clara, Pascual-Font, Arán, Mancuso, Renzo, Forés, Joaquim, Casas, Caty, Navarro, Xavier

“…Spinal root avulsion leads to a progressive loss of axotomized motoneurons (MNs). Nowadays, there is no effective treatment to prolong MN survival that could…”
Get more information

Repair of Long Nerve Defects with a New Decellularized Nerve Graft in Rats and in Sheep by Contreras, Estefanía, Traserra, Sara, Bolívar, Sara, Forés, Joaquim, Jose-Cunilleras, Eduard, García, Felix, Delgado-Martínez, Ignacio, Holmgren, Sandra, Strehl, Raimund, Udina, Esther, Navarro, Xavier

“…Decellularized nerve allografts (DC) are an alternative to autografts (AG) for repairing severe peripheral nerve injuries. We have assessed a new DC provided…”
Get full text

Spinal cord injury induces endoplasmic reticulum stress with different cell-type dependent response by Penas, Clara, Guzmán, Mónica-Sofía, Verdú, Enrique, Forés, Joaquim, Navarro, Xavier, Casas, Caty

“…The mechanisms of injury-induced apoptosis of neurons within the spinal cord are poorly understood. In this study, we show that spinal cord injury (SCI)…”
Get full text

ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons by Leiva-Rodríguez, Tatiana, Romeo-Guitart, David, Marmolejo-Martínez-Artesero, Sara, Herrando-Grabulosa, Mireia, Bosch, Assumpció, Forés, Joaquim, Casas, Caty

“…Injured neurons should engage endogenous mechanisms of self-protection to limit neurodegeneration. Enhancing efficacy of these mechanisms or correcting…”
Get full text

GRP78 Overexpression Triggers PINK1-IP3R-Mediated Neuroprotective Mitophagy by Leiva-Rodríguez, Tatiana, Romeo-Guitart, David, Herrando-Grabulosa, Mireia, Muñoz-Guardiola, Pau, Polo, Miriam, Bañuls, Celia, Petegnief, Valerie, Bosch, Assumpció, Lizcano, Jose Miguel, Apostolova, Nadezda, Forés, Joaquim, Casas, Caty

“…An experimental model of spinal root avulsion (RA) is useful to study causal molecular programs that drive retrograde neurodegeneration after neuron-target…”
Get full text

Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage by Casas, Caty, Isus, Laura, Herrando-Grabulosa, Mireia, Mancuso, Francesco M., Borrás, Eva, Sabidó, Eduardo, Forés, Joaquim, Aloy, Patrick

“…Neurodegenerative processes are preceded by neuronal dysfunction and synaptic disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic…”
Get full text

Cytoskeletal and activity-related changes in spinal motoneurons after root avulsion by Penas, Clara, Casas, Caty, Robert, Ivan, Forés, Joaquim, Navarro, Xavier

“…Compelling evidence shows that after root avulsion motoneurons attempt to survive and regenerate before dying. In order to study these mechanisms, unilateral…”
Get more information

Neuroprotection and Axonal Regeneration After Lumbar Ventral Root Avulsion by Re-implantation and Mesenchymal Stem Cells Transplant Combined Therapy by Torres-Espín, Abel, Corona-Quintanilla, Dora Luz, Forés, Joaquim, Allodi, Ilary, González, Francisco, Udina, Esther, Navarro, Xavier

“…Ventral spinal root avulsion causes complete denervation of muscles in the limb and also progressive death of segmental motoneurons (MN) leading to permanent…”
Get full text

Improved prediction of knee osteoarthritis progression by genetic polymorphisms: the Arthrotest Study by Blanco, Francisco J, Möller, Ingrid, Romera, Montserrat, Rozadilla, Antoni, Sánchez-Lázaro, Jaime A, Rodríguez, Arturo, Gálvez, José, Forés, Joaquim, Monfort, Jordi, Ojeda, Soledad, Moragues, Carme, Caracuel, Miguel Ángel, Clavaguera, Teresa, Valdés, Carmen, Soler, Josep Maria, Orellana, Cristóbal, Belmonte, Miguel Ángel, Martín, Florentina, Giménez, Sergio, Úcar, Eduardo, Pous, Josep, Bartolomé, Nerea, Artieda, Marta, Szczypiorska, Magdalena, Tejedor, Diego, Martínez, Antonio, Montell, Eulàlia, Martínez, Helena, Herrero, Marta, Vergés, Josep

“…The aim of this study was to develop a genetic prognostic tool to predict radiographic progression towards severe disease in primary knee OA (KOA) patients…”
Get full text

Reorganization of Reflex Responses Mediated by Different Afferent Sensory Fibers After Spinal Cord Transection by Valero-Cabre, Antoni, Fores, Joaquim, Navarro, Xavier

“…1 Laboratory for Magnetic Brain Stimulation, Department of Neurology, Harvard Medical School-Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215,…”
Get full text