Search Results - "Foo, Roger SY"
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Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated
Published in BMC genomics (27-09-2010)“…DNA methylation can regulate gene expression by modulating the interaction between DNA and proteins or protein complexes. Conserved consensus motifs exist…”
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The Role Played by Transcription Factor E3 in Modulating Cardiac Hypertrophy
Published in International Heart Journal (29-11-2021)“…Transcription factor E3 (TFE3), which is a key regulator of cellular adaptation, is expressed in most tissues, including the heart, and is reportedly…”
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Persistent changes in liver methylation and microbiome composition following reversal of diet-induced non-alcoholic-fatty liver disease
Published in Cellular and molecular life sciences : CMLS (01-11-2019)“…Non-alcoholic fatty liver disease (NAFLD) is a metabolic liver disease that is thought to be reversible by changing the diet. To examine the impact of dietary…”
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Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells
Published in eLife (02-01-2024)“…Selection of the target site is an inherent question for any project aiming for directed transgene integration. Genomic safe harbour (GSH) loci have been…”
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Prioritizing Candidates of Post–Myocardial Infarction Heart Failure Using Plasma Proteomics and Single-Cell Transcriptomics
Published in Circulation (New York, N.Y.) (13-10-2020)“…BACKGROUND:Heart failure (HF) is the most common long-term complication of acute myocardial infarction (MI). Understanding plasma proteins associated with…”
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Consuming Wolfberry (Lycium Barbarum L.) with a Healthy Dietary Pattern Improves the Function of Blood Outgrowth Endothelial Cells Derived from Middle-Aged and Older Adults
Published in Current developments in nutrition (01-06-2020)“…Endothelial progenitor cells (EPCs), a novel biomarker of cardiovascular disease, are involved in the maintenance of endothelial homeostasis and vascular…”
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