Search Results - "Fontes, Ana Paula S."
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Novel gold(I) complexes with 5-phenyl-1,3,4-oxadiazole-2-thione and phosphine as potential anticancer and antileishmanial agents
Published in European journal of medicinal chemistry (15-02-2017)“…The current anticancer and antileishmanial drug arsenal presents several limitations concerning their specificity, efficacy, costs and the emergence of…”
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Palladium(II)–Copper(II) Assembling with Bis(2-pyridylcarbonyl)amidate and Bis(oxamate) Type Ligands
Published in Crystal growth & design (04-03-2015)“…Five new complexes of formula K4[Pd2(mpba)2] · 4H2O (1), {[K4(H2O)(dmso)][Pd2(mpba)2]} (2), {[Cu(bpca)]4[Pd2(mpba)2]} · 6H2O (3), {[Cu(bpca)]2[Pd(opba)]} ·…”
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3
Synthesis and antitubercular activity of palladium and platinum complexes with fluoroquinolones
Published in European journal of medicinal chemistry (01-10-2009)“…The fluoroquinolones are an important family of synthetic antimicrobial agents being clinically used over the past thirty years. In addition, some…”
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Improved pharmacological profile of the lipophilic antitumor dichloro-(N-dodecyl)-propanediamine-platinum(II) complex after incorporation into pegylated liposomes
Published in Anti-cancer drugs (01-02-2013)“…Liposome encapsulation of platinum (Pt) drugs has emerged as a promising strategy to overcome their toxicity and cellular Pt resistance. The aim of the present…”
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5
Synthesis of platinum complexes from N-benzyl ethylenediamine derivatives
Published in Journal of the Brazilian Chemical Society (01-04-2000)“…N-benzylethylenediamine derivatives have been prepared in good yields using methodology diferent than that described in the literature. ¹H and 13C NMR spectra…”
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Synthesis and cytotoxic activity of gold(I) complexes containing phosphines and 3-benzyl-1,3-thiazolidine-2-thione or 5-phenyl-1,3,4-oxadiazole-2-thione as ligands
Published in Inorganica Chimica Acta (01-04-2014)“…[C28H26NPS2Au]Cl (1), [C16H26NPS2Au]Cl (2), C26H20N2OPSAu (3) and C14H20N2OPSAu (4) were obtained with 3-benzyl-1,3-thiazolidine-2-thione or…”
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Liposome encapsulation of lipophilic N-alkyl-propanediamine platinum complexes: impact on their cytotoxic activity and influence of the carbon chain length
Published in Journal of the Brazilian Chemical Society (2010)“…Antitumor platinum(II) complexes derived from N-alkyl-propanediamine differing in the length of their carbon chain (C8, C10, C12 and C14) were incorporated in…”
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Novel platinum(II) complexes of long chain aliphatic diamine ligands with oxalato as the leaving group: comparative cytotoxic activity relative to chloride precursors
Published in Journal of the Brazilian Chemical Society (2010)“…Platinum complexes play an important role in the development of anticancer drugs. Their cytotoxicity can be influenced by the nature of the leaving ligands,…”
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