Search Results - "Fontenot, JD"

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3 by Fontenot, Jason D, Rudensky, Alexander Y

“…The random generation of antigen receptors in developing lymphocytes results in a considerable risk of autoimmunity. Regulatory T cells (T(reg) cells) act in a…”
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A function for interleukin 2 in Foxp3-expressing regulatory T cells by Fontenot, Jason D, Rudensky, Alexander Y, Rasmussen, Jeffrey P, Gavin, Marc A

“…Regulatory T cells (T(reg) cells) expressing the forkhead family transcription factor Foxp3 are critical mediators of dominant immune tolerance to self. Most…”
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Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3 by Fontenot, Jason D., Rasmussen, Jeffrey P., Williams, Luke M., Dooley, James L., Farr, Andrew G., Rudensky, Alexander Y.

“…Regulatory T cell-mediated dominant tolerance has been demonstrated to play an important role in the prevention of autoimmunity. Here, we present data arguing…”
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An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires by Hsieh, Chyi-Song, Rudensky, Alexander Y, Zheng, Ye, Liang, Yuqiong, Fontenot, Jason D

“…The relationship between the T cell receptor (TCR) repertoires used by self-reactive transcription factor Foxp3-positive (Foxp3(+)) CD4(+) regulatory T cells…”
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Developmental regulation of Foxp3 expression during ontogeny by Fontenot, Jason D, Dooley, James L, Farr, Andrew G, Rudensky, Alexander Y

“…Thymectomy of neonatal mice can result in the development of autoimmune pathology. It has been proposed that thymic output of regulatory T (T reg) cells is…”
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Structure-based design of peptides that recognize the CD4 binding domain of HIV-1 gp120 by FONTENOT, J. D, XIN TAN, PHILLIPS, D. M

“…Envelope protein-specific antiviral peptides, called mucibodies, that can specifically recognize and bind to the surface unit protein gp120 of HIV-1 were…”
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The Repertoire for Pattern Recognition of Pathogens by the Innate Immune System is Defined by Cooperation between Toll-Like Receptors by Ozinsky, A, Underhill, D M, Fontenot, J D, Hajjar, A M, Smith, K D, Wilson, C B, Schroeder, L, Aderem, A

“…Toll-like receptors (TLRs) have been shown to participate in the recognition of pathogens by the innate immune system, but it is not clear how a restricted…”
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SU‐E‐T‐549: Validation of a Commercial Model‐Based Collapsed Cone Dose Algorithm for High Dose‐Rate Gynecological Brachytherapy Treatment Planning by Price, MJ, Fontenot, JD

“…Purpose: To evaluate the accuracy of calculations from a model‐based collapsed cone (MBCC) dose calculation algorithm developed for high dose‐rate…”
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SU‐E‐T‐485: Comparison of the Oncogenic Potential for Radiation‐Associated, Second Malignant Neoplasms for Several Prostate Radiotherapy Modalities as a Function of Relative OAR & PTV Volumes by Price, MJ, Fontenot, JD, Lian, J, Nichols, G, Burkhardt, K, Erwin, R, VanderWalde, N, Dooley, J, Tracton, G, Chang, S

“…Purpose: To compare plan quality for a comprehensive set of OAR & PTV geometries considering relative risk estimates for the induction of secondary bladder and…”
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Molecular aspects of regulatory T cell development by Fontenot, Jason D, Rudensky, Alexander Y

“…Naturally arising CD4 + regulatory T cells are critical mediators of peripheral self tolerance and immune homeostasis. Emerging evidence suggests that these…”
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Design tools for proton therapy nozzles based on the double-scattering foil technique by Fontenot, J. D., Newhauser, W. D., Titt, U.

“…Proton therapy has been increasing over the past several years, with several new treatment facilities being built in Europe, Japan and the United States. In…”
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Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients by KOTERA, Y, FONTENOT, J. D, PECHER, G, METZGAR, R. S, FINN, O. J

“…Using synthetic peptides 60,80, and 105 residues long, corresponding to 3, 4, and 5.25 tandem repeats of human mucin MUC-1 protein core, as antigens in a…”
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SU‐GG‐AUD‐06: Stray Radiation Exposure During Proton Radiotherapy of the Prostate: The Influence of the Patient On Scatter and Production by Fontenot, JD, Zheng, Y, Taddei, P, Newhauser, W

“…Purpose: To characterize the scatter, production, and attenuation of secondary radiation in patients receiving passively‐scattered proton radiotherapy for…”
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SU‐FF‐T‐457: Second Cancer Risk From Secondary Neutrons for a Boy Who Received Proton Craniospinal Irradiation by Taddei, PJ, Mirkovic, D, Fontenot, JD, Giebeler, A, Zheng, Y, Kornguth, D, Mohan, R, Newhauser, WD

“…Purpose: Proton fields used in radiotherapy expose healthy tissue to secondary neutrons emanating from the treatment unit (or “external neutrons”) and produced…”
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Local and Global Structural Properties of the HIV-MN V3 Loop (∗) by Catasti, Paolo, Fontenot, J. Darrell, Bradbury, E. Morton, Gupta, Goutam

“…Studies of the feasibility of a subunit vaccine to protect against human immunodeficiency virus (HIV) infection have principally focused on the third variable…”
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Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women by RICHARDS, E. R, DEVINE, P. L, QUIN, R. J, FONTENOT, J. D, WARD, B. G, MCGUCKIN, M. A

“…Antibodies reactive with peptide epitopes on the core protein of MUC1 epithelial mucin have been demonstrated in some patients with adenocarcinomas. Because…”
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Overestimation of hemoglobin in a patient with an IgA-kappa monoclonal gammopathy by Roberts, W L, Fontenot, J D, Lehman, C M

“…A patient with multiple myeloma had an automated blood count performed on a Coulter STK-S counter that repeatedly failed internal limits for both mean…”
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Structure of a tumor associated antigen containing a tandemly repeated immunodominant epitope by Fontenot, J D, Mariappan, S V, Catasti, P, Domenech, N, Finn, O J, Gupta, G

“…Human mucins are T or S glycosylated tandem repeat proteins. In breast cancer, mucins become under or unglycosylated. Two-dimensional nuclear magnetic…”
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N-acetylgalactosamine glycosylation of MUC1 tandem repeat peptides by pancreatic tumor cell extracts by NISHIMORI, I, PERINI, F, MOUNTJOY, K. P, SANDERSON, S. D, JOHNSON, N, CERNY, R. L, GROSS, M. L, FONTENOT, J. D, HOLLINGSWORTH, M. A

“…Synthetic peptides corresponding to the human mucin MUC1 tandem repeat domain (20 residues) were glycosylated in vitro by using…”
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Isolation and characterization of a proteoglycan variant from human aorta exhibiting a marked affinity for low density lipoprotein and demonstration of its enhanced expression in atherosclerotic plaques by Vijayagopal, Parakat, Figueroa, Julio E., Fontenot, Jason D., Glancy, D.Luke

“…Proteoglycans (PG) are implicated in the pathophysiology of atherosclerosis due to their ability to complex with plasma low density lipoproteins (LDL). Studies…”
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