Search Results - "Fonteneau, Jean‐François"

Endogenous retrovirus expression activates type-I interferon signaling in an experimental mouse model of mesothelioma development by Sun, Suna, Frontini, Francesca, Qi, Weihong, Hariharan, Ananya, Ronner, Manuel, Wipplinger, Martin, Blanquart, Christophe, Rehrauer, Hubert, Fonteneau, Jean-François, Felley-Bosco, Emanuela

“…Early events in an experimental model of mesothelioma development include increased levels of editing in double-stranded RNA (dsRNA). We hypothesised that…”
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Measles Virus Vaccine―Infected Tumor Cells Induce Tumor Antigen Cross-Presentation by Human Plasmacytoid Dendritic Cells by GUILLERME, Jean-Baptiste, BOISGERAULT, Nicolas, ROULOIS, David, MENAGER, Jérémie, COMBREDET, Chantal, TANGY, Frédéric, FONTENEAU, Jean-François, GREGOIRE, Marc

“…Plasmacytoid dendritic cells (pDC) are antigen-presenting cells specialized in antiviral response. The measles virus vaccine is proposed as an antitumor agent…”
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Use of non-small cell lung cancer multicellular tumor spheroids to study the impact of chemotherapy by Hulo, Pauline, Deshayes, Sophie, Fresquet, Judith, Chéné, Anne-Laure, Blandin, Stéphanie, Boisgerault, Nicolas, Fonteneau, Jean-François, Treps, Lucas, Denis, Marc G, Bennouna, Jaafar, Fradin, Delphine, Pons-Tostivint, Elvire, Blanquart, Christophe

“…Lung cancers represent the main cause of cancer related-death worldwide. Recently, immunotherapy alone or in combination with chemotherapy has deeply impacted…”
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A spliced antigenic peptide comprising a single spliced amino acid is produced in the proteasome by reverse splicing of a longer peptide fragment followed by trimming by Michaux, Alexandre, Larrieu, Pierre, Stroobant, Vincent, Fonteneau, Jean-François, Jotereau, Francine, Van den Eynde, Benoît J, Moreau-Aubry, Agnès, Vigneron, Nathalie

“…Peptide splicing is a novel mechanism of production of peptides relying on the proteasome and involving the linkage of fragments originally distant in the…”
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Human Immunodeficiency Virus Type 1 Activates Plasmacytoid Dendritic Cells and Concomitantly Induces the Bystander Maturation of Myeloid Dendritic Cells by FONTENEAU, Jean-Francois, LARSSON, Marie, BEIGNON, Anne-Sophie, MCKENNA, Kelli, DASILVA, Ida, AMARA, Ali, LIU, Yong-Jun, LIFSON, Jeffrey D, LITTMAN, Dan R, BHARDWAJ, Nina

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Homozygous Co-Deletion of Type I Interferons and CDKN2A Genes in Thoracic Cancers: Potential Consequences for Therapy by Grard, Marion, Chatelain, Camille, Delaunay, Tiphaine, Pons-Tostivint, Elvire, Bennouna, Jaafar, Fonteneau, Jean-François

“…Homozygous deletion (HD) of the tumor suppressor gene CDKN2A is the most frequent genetic alteration in malignant pleural mesothelioma and is also frequent in…”
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The DCMU Herbicide Shapes T-cell Functions By Modulating Micro-RNA Expression Profiles by Autin, Pierre, Deshayes, Sophie, Lea, Juliette, Boisgerault, Nicolas, Dupré, Emilie, Labarrière, Nathalie, Leguevel, Rémy, Fonteneau, Jean-François, Blanquart, Christophe, Fradin, Delphine

“…DCMU [N-(3,4-dichlorophenyl)-N-dimethylurea] or diuron is a widely used herbicide, which can cause adverse effects on human, especially on immune cells, due to…”
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Loss of miR-200c-3p promotes resistance to radiation therapy via the DNA repair pathway in prostate cancer by Labbé, Maureen, Chang, Manon, Saintpierre, Benjamin, Letourneur, Franck, de Beaurepaire, Laurence, Véziers, Joëlle, Deshayes, Sophie, Cotinat, Marine, Fonteneau, Jean-François, Blanquart, Christophe, Potiron, Vincent, Supiot, Stéphane, Fradin, Delphine

“…Radiotherapy represents a major curative treatment for prostate cancer (PCa), but some patients will develop radioresistance (RR) and relapse. The underlying…”
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Activation of influenza virus–specific CD4+ and CD8+ T cells: a new role for plasmacytoid dendritic cells in adaptive immunity by Fonteneau, Jean-François, Gilliet, Michel, Larsson, Marie, Dasilva, Ida, Münz, Christian, Liu, Yong-Jun, Bhardwaj, Nina

“…Plasmacytoid dendritic cells (pDCs) contribute to innate antiviral immune responses by producing type I interferons (IFNs) upon exposure to enveloped viruses…”
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A Functional Assay to Determine the Capacity of Oncolytic Viruses to Induce Immunogenic Tumor Cell Death by Delaunay, Tiphaine, Achard, Carole, Grégoire, Marc, Tangy, Frédéric, Boisgerault, Nicolas, Fonteneau, Jean-François

“…Oncolytic immunotherapy efficacy relies partially on the induction of immunogenic tumor cell death following infection with oncolytic viruses (OV) to induce an…”
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MUC1-Specific Cytotoxic T Lymphocytes in Cancer Therapy: Induction and Challenge by Roulois, David, Fonteneau, Jean-François, Grégoire, Marc

“…MUC1 glycoprotein is often found overexpressed and hypoglycosylated in tumor cells from numerous cancer types. Since its discovery MUC1 has been an attractive…”
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Involvement of the M-CSF/IL-34/CSF-1R pathway in malignant pleural mesothelioma by Blondy, Thibaut, d'Almeida, Sènan Mickael, Briolay, Tina, Tabiasco, Julie, Meiller, Clément, Chéné, Anne-Laure, Cellerin, Laurent, Deshayes, Sophie, Delneste, Yves, Fonteneau, Jean-François, Boisgerault, Nicolas, Bennouna, Jaafar, Grégoire, Marc, Jean, Didier, Blanquart, Christophe

“…BackgroundMalignant pleural mesothelioma (MPM) is a rare and aggressive cancer related to asbestos exposure. The tumor microenvironment content, particularly…”
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Interplay between oncolytic measles virus, macrophages and cancer cells induces a proinflammatory tumor microenvironment by Chatelain, Camille, Berland, Laurine, Grard, Marion, Jouand, Nicolas, Fresquet, Judith, Nader, Joëlle, Hirigoyen, Ugo, Petithomme, Tacien, Combredet, Chantal, Pons-Tostivint, Elvire, Fradin, Delphine, Treps, Lucas, Blanquart, Christophe, Boisgerault, Nicolas, Tangy, Frédéric, Fonteneau, Jean-François

“…Attenuated measles virus (MV) exerts its oncolytic activity in malignant pleural mesothelioma (MPM) cells that lack type-I interferon (IFN-I) production or…”
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Sensitivity of human pleural mesothelioma to oncolytic measles virus depends on defects of the type I interferon response by Achard, Carole, Boisgerault, Nicolas, Delaunay, Tiphaine, Roulois, David, Nedellec, Steven, Royer, Pierre-Joseph, Pain, Mallory, Combredet, Chantal, Mesel-Lemoine, Mariana, Cellerin, Laurent, Magnan, Antoine, Tangy, Frédéric, Grégoire, Marc, Fonteneau, Jean-François

“…Attenuated measles virus (MV) is currently being evaluated as an oncolytic virus in clinical trials and could represent a new therapeutic approach for…”
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Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways by Charrier, Marine, Lorant, Judith, Contreras-Lopez, Rafael, Téjédor, Gautier, Blanquart, Christophe, Lieubeau, Blandine, Schleder, Cindy, Leroux, Isabelle, Deshayes, Sophie, Fonteneau, Jean-François, Babarit, Candice, Hamel, Antoine, Magot, Armelle, Péréon, Yann, Viau, Sabrina, Delorme, Bruno, Luz-Crawford, Patricia, Lamirault, Guillaume, Djouad, Farida, Rouger, Karl

“…Muscular dystrophies (MDs) are inherited diseases in which a dysregulation of the immune response exacerbates disease severity and are characterized by…”
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Viral cancer therapies: are they ready for combination with other immunotherapies? by Boisgerault, Nicolas, Grégoire, Marc, Fonteneau, Jean-François

“…Due to their ability to specifically target and kill cancer cells without replicating in the healthy ones, they have been extensively studied over the last two…”
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Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells by Delaunay, Tiphaine, Violland, Mathilde, Boisgerault, Nicolas, Dutoit, Soizic, Vignard, Virginie, Münz, Christian, Gannage, Monique, Dréno, Brigitte, Vaivode, Kristine, Pjanova, Dace, Labarrière, Nathalie, Wang, Yaohe, Chiocca, E. Antonio, Boeuf, Fabrice Le, Bell, John C., Erbs, Philippe, Tangy, Frédéric, Grégoire, Marc, Fonteneau, Jean-François

“…Oncolytic immunotherapy using oncolytic viruses (OV) has been shown to stimulate the antitumor immune response by inducing the release of tumor-associated…”
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Downregulation of MUC1 expression and its recognition by CD8+ T cells on the surface of malignant pleural mesothelioma cells treated with HDACi by Roulois, David, Blanquart, Christophe, Panterne, Clarisse, Gueugnon, Fabien, Grégoire, Marc, Fonteneau, Jean‐François

“…Research into new treatments against malignant pleural mesothelioma (MPM) is of great interest, as this aggressive cancer is often resistant to conventional…”
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Oncolytic viruses alter the biogenesis of tumor extracellular vesicles and influence their immunogenicity by Hirigoyen, Ugo, Guilbaud, Coraly, Krejbich, Morgane, Fouet, Morgane, Fresquet, Judith, Arnaud, Bastien, Com, Emmanuelle, Pineau, Charles, Cadiou, Gwenann, Burlaud-Gaillard, Julien, Erbs, Philippe, Fradin, Delphine, Labarrière, Nathalie, Fonteneau, Jean-François, Petithomme, Tacien, Boisgerault, Nicolas

“…Extracellular vesicles (EVs) are mediators of intercellular communication in the tumor microenvironment. Tumor EVs are commonly associated with metastasis,…”
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Viral Mimicry Response Is Associated With Clinical Outcome in Pleural Mesothelioma by Sun, Suna, Qi, Weihong, Rehrauer, Hubert, Ronner, Manuel, Hariharan, Ananya, Wipplinger, Martin, Meiller, Clément, Stahel, Rolf, Früh, Martin, Cerciello, Ferdinando, Fonteneau, Jean-François, Jean, Didier, Felley-Bosco, Emanuela

“…The aim of this study was to investigate endogenous retrovirus (ERV) expression and type I interferon (IFN) activation in human pleural mesothelioma (PM) and…”
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