Search Results - "Fonteh, A. N."

Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects by Fonteh, A. N, Harrington, R. J, Tsai, A, Liao, P, Harrington, M. G

“…Our aim was to determine changes in free amino acid (FAA) and dipeptide (DP) concentrations in probable Alzheimer's disease (pAD) subjects compared with…”
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Urine dicarboxylic acids change in pre-symptomatic Alzheimer's disease and reflect loss of energy capacity and hippocampal volume by Castor, K J, Shenoi, S, Edminster, S P, Tran, T, King, K S, Chui, H, Pogoda, J M, Fonteh, A N, Harrington, M G

“…Non-invasive biomarkers will enable widespread screening and early diagnosis of Alzheimer's disease (AD). We hypothesized that the considerable loss of brain…”
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Quantification of free amino acids and dipeptides using isotope dilution liquid chromatography and electrospray ionization tandem mass spectrometry by Fonteh, A. N, Harrington, R. J, Harrington, M. G

“…Our aim was to develop a liquid chromatography and electrospray ionization tandem mass spectrometry (LCMS²) method to measure free amino acid (FAA) and…”
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Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells by Clay, Carl E., Namen, Andrew M., Atsumi, Gen-ichi, Willingham, Mark C., High, Kevin P., Kute, Timothy E., Trimboli, Anthony J., Fonteh, Alfred N., Dawson, Paul A., Chilton, Floyd H.

“…This study was undertaken to investigate the influence of the peroxisome proliferator-activated receptor γ (PPARγ) agonists on the proliferation, apoptosis and…”
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Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans by Barham, J B, Edens, M B, Fonteh, A N, Johnson, M M, Easter, L, Chilton, F H

“…Previous studies reveal that supplementation of human diets with gamma-linolenic acid (GLA) reduces the generation of lipid mediators of inflammation and…”
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Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans by Johnson, M M, Swan, D D, Surette, M E, Stegner, J, Chilton, T, Fonteh, A N, Chilton, F H

“…To understand the in vivo metabolism of dietary gamma-linolenic acid (GLA), we supplemented the diets of 29 volunteers with GLA in doses of 1.5-6.0 g/d…”
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Magnitude of Peroxisome Proliferator-Activated Receptor-γ Activation is Associated With Important and Seemingly Opposite Biological Responses in Breast Cancer Cells by Clay, Carl E., Namen, Andrew M., Atsumi, Gen-ichi, Trimboli, Anthony J., Fonteh, Alfred N., High, Kevin P., Chilton, Floyd H.

“…BackgroundThe nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) has become a potential target for the prevention and treatment of breast…”
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Perturbations in the control of cellular arachidonic acid levels block cell growth and induce apoptosis in HL-60 cells by Surette, Marc E., Fonteh, Alfred N., Bernatchez, Chantale, Chilton, Floyd H.

“…Our previous studies demonstrated that inhibitors of arachidonate–phospholipid remodeling [i.e. the enzyme CoA-independent transacylase (CoA-IT)] decrease cell…”
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Amniotic fluid levels of phospholipase A2 in fetal rats with retinoic acid induced myelomeningocele: the potential "second hit" in neurologic damage by Agarwal, R., Thornton, M. E., Fonteh, A. N., Harrington, M. G., Chmait, R. H., Grubbs, B. H.

“…Objectives: There is growing evidence of ongoing, in utero neurological damage in fetuses with myelomeningocele (MMC). Phospholipase A 2 (PLA 2 ) has known…”
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Fatty acid and phospholipid selectivity of different phospholipase A2 enzymes studied by using a mammalian membrane as substrate by Diez, E, Chilton, F H, Stroup, G, Mayer, R J, Winkler, J D, Fonteh, A N

“…Previous studies using phospholipid mixed vesicles have demonstrated that several types of phospholipase A2 (PLA2) enzymes exhibit different selectivity for…”
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Antigen-induced generation of lyso-phospholipids in human airways by Chilton, F H, Averill, F J, Hubbard, W C, Fonteh, A N, Triggiani, M, Liu, M C

“…The goal of the current study was to examine the formation of phospholipids, 1-radyl-2-lysosn-glycero-phospholipids (lyso-PL) and 2-acetylated phospholipids…”
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Evidence that secretory phospholipase A2 plays a role in arachidonic acid release and eicosanoid biosynthesis by mast cells by Fonteh, AN, Bass, DA, Marshall, LA, Seeds, M, Samet, JM, Chilton, FH

“…This study investigated the role of secretory PLA2 (sPLA2) in arachidonic acid (AA) release and lipid mediator generation in mouse bone marrow-derived mast…”
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Rapid remodeling of arachidonate from phosphatidylcholine to phosphatidylethanolamine pools during mast cell activation by Fonteh, AN, Chilton, FH

“…The objective of the present study was to better understand the remodeling of arachidonic acid (AA) in phospholipids of the mouse bone marrow-derived mast cell…”
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Dietary n-3 fatty acid effects on neutrophil lipid composition and mediator production : influence of duration and dosage by CHILTON, F. H, PATEL, M, FONTEH, A. N, HUBBARD, W. C, TRIGGIANI, M

“…Healthy volunteers supplemented their usual Western diets with Promega fish oil supplement (eicosapentaenoic acid [EPA], 0.28 g; docosahexaenoic acid [DCHA],…”
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Effects of CoA-independent transacylase inhibitors on the production of lipid inflammatory mediators by Winkler, J D, Fonteh, A N, Sung, C M, Heravi, J D, Nixon, A B, Chabot-Fletcher, M, Griswold, D, Marshall, L A, Chilton, F H

“…The enzyme CoA-independent transacylase (CoA-IT) has been proposed to mediate the movement of arachidonate between specific phospholipid subclasses, and we…”
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Metabolism of gammalinolenic acid in human neutrophils by Chilton-Lopez, Surette, ME, Swan, DD, Fonteh, AN, Johnson, MM, Chilton, FH

“…Gammalinolenic acid (GLA), when provided as a dietary supplement, has been reported to improve clinical symptoms of several inflammatory disorders. The goal of…”
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Control of arachidonate levels within inflammatory cells by Chilton, Floyd H., Fonteh, Alfred N., Surette, Marc E., Triggiani, Massimo, Winkler, James D.

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Role of Arachidonyl Triglycerides within Lipid Bodies in Eicosanoid Formation by Human Polymorphonuclear Cells by Johnson, Margaret M, Vaughn, Benjamin, Triggiani, Massimo, Swan, Dennis D, Fonteh, Alfred N, Chilton, Floyd H

“…Increasing evidence suggests that the subcellular and glycerolipid localization of esterified arachidonic acid (AA) is a key factor in regulating its…”
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Influence of coenzyme A-independent transacylase and cyclooxygenase inhibitors on the proliferation of breast cancer cells by TRIMBOLI, A. J, WAITE, B. M, ATSUMI, G.-I, FONTEH, A. N, NAMEN, A. M, CLAY, C. E, KUTE, T. E, HIGH, K. P, WILLINGHAM, M. C, CHILTON, F. H

“…Recent studies have demonstrated that arachidonic acid (AA) may serve as an important signal that blocks cell proliferation of certain neoplastic cells. The…”
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Mobilization of different arachidonate pools and their roles in the generation of leukotrienes and free arachidonic acid during immunologic activation of mast cells by FONTEH, A. N, CHILTON, F. H

“…Immunologic activation of mast cells leads to the mobilization of arachidonic acid (AA) from membrane phospholipids and the subsequent conversion of this AA to…”
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