Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile

Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile

In a national prospective cohort study involving 10.2 million participants in Chile, the effectiveness of an inactivated SARS-CoV-2 vaccine, which had been developed in China and administered in two doses 28 days apart, was estimated. Effectiveness among fully immunized persons was estimated at 65.9...

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Bibliographic Details
Published in:The New England journal of medicine Vol. 385; no. 10; pp. 875 - 884
Main Authors: Jara, Alejandro, Undurraga, Eduardo A, González, Cecilia, Paredes, Fabio, Fontecilla, Tomás, Jara, Gonzalo, Pizarro, Alejandra, Acevedo, Johanna, Leo, Katherinne, Leon, Francisco, Sans, Carlos, Leighton, Paulina, Suárez, Pamela, García-Escorza, Heriberto, Araos, Rafael
Format: Journal Article
Language:English
Published: Boston Massachusetts Medical Society 02-09-2021
Subjects:
Age
Alzheimer's disease
Blood diseases
Clinical trials
Coronavirus
Coronaviruses
COVID-19
COVID-19 vaccines
Death
Decision making
Estimates
Fatalities
Health care
Health care policy
Infections
Infectious Disease
Laboratories
Original
Pandemics
Population
Public health
Schedules
Severe acute respiratory syndrome coronavirus 2
Vaccination
Vaccine efficacy
Vaccines
Brazil
Turkey
Chile
United States > US
Indonesia
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Summary:In a national prospective cohort study involving 10.2 million participants in Chile, the effectiveness of an inactivated SARS-CoV-2 vaccine, which had been developed in China and administered in two doses 28 days apart, was estimated. Effectiveness among fully immunized persons was estimated at 65.9% for Covid-19 and at 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.
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Drs. Jara, Undurraga, and Araos contributed equally to this article.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa2107715