Search Results - "Fontaine, Vincent"

Generation of CRISPR-Cas9 edited human induced pluripotent stem cell line carrying BAG3 V468M mutation in its BAG domain by Duboscq-Bidot, Laetitia, Hoareau, Bénédicte, Ader, Flavie, Fontaine, Vincent, Villard, Eric

“…BCL2-Associated Athanogene 3 (BAG3) gene was identified mutated in patients with dilated cardiomyopathy (DCM), an important cause of heart failure and…”
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Generation of CRISPR/Cas9 edited human induced pluripotent stem cell line carrying the heterozygous p.H695VfsX5 frameshift mutation in the exon 10 of the PKP2 gene by Bobin, Pierre, Duboscq-Bidot, Laëtitia, Blandin, Camille, Perret, Claire, Balse, Elise, Gandjbakhch, Estelle, Fontaine, Vincent, Villard, Eric

“…Loss-of-function mutations in the PKP2 gene are associated with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare cardiac disease associated with…”
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Performances of Hybridized-, Embedded-, and Weighted-Interior Penalty Discontinuous Galerkin Methods for Heterogeneous and Anisotropic Diffusion Problems by Etangsale, Grégory, Fontaine, Vincent, Rajaonison, Nalitiana

“…The present paper discusses families of Interior Penalty Discontinuous Galerkin (IP) methods for solving heterogeneous and anisotropic diffusion problems…”
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Generation of CRISPR-Cas9 edited human induced pluripotent stem cell line carrying FLNC exon skipping variant by Ader, Flavie, Duboscq-Bidot, Laetitia, Marteau, Sibylle, Hamlin, Matthieu, Richard, Pascale, Fontaine, Vincent, Villard, Eric

“…•FLNC hiPSC line useable for cardiomyocytes differenciation and heart tissu production.•Isogenic pair of iPSc generated through CRISPR/Cas9 Non-Homologous End…”
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Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition by Gizon, Marie, Duboscq-Bidot, Laëtitia, El Kassar, Lina, Bobin, Pierre, Ader, Flavie, Giraud-Triboult, Karine, Charron, Philippe, Villard, Eric, Fontaine, Vincent, Neyroud, Nathalie

“…Mutations leading to haploinsufficiency in SCN5A, the gene encoding the cardiac sodium channel Nav1.5 α-subunit, are involved in life-threatening cardiac…”
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Generation of iPSC line from MYH7 R403L mutation carrier with severe hypertrophic cardiomyopathy and isogenic CRISPR/Cas9 corrected control by Fontaine, Vincent, Duboscq-Bidot, Laetitia, Jouve, Charlène, Hamlin, Matthieu, Curjol, Angélique, Briand, Véronique, Janiak, Philip, Hulot, Jean-Sébastien, Pruniaux-Harnist, Marie-Pierre, Charron, Philippe, Villard, Eric

“…MYH7 is a major gene responsible for hypertrophic cardiomyopathy (HCM). From patient’s skin fibroblasts, we derived an iPSC line (CDGEN1.16) harboring the…”
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Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols by Jeziorowska, Dorota, Fontaine, Vincent, Jouve, Charlène, Villard, Eric, Dussaud, Sébastien, Akbar, David, Letang, Valérie, Cervello, Pauline, Itier, Jean-Michiel, Pruniaux, Marie-Pierre, Hulot, Jean-Sébastien

“…Human induced pluripotent stem cells (iPSCs) represent a powerful human model to study cardiac disease in vitro, notably channelopathies and sarcomeric…”
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Involvement of the Mural Thrombus as a Site of Protease Release and Activation in Human Aortic Aneurysms by Fontaine, Vincent, Jacob, Marie-Paule, Houard, Xavier, Rossignol, Patrick, Plissonnier, Didier, Angles-Cano, Eduardo, Michel, Jean-Baptiste

“…Acquired abdominal aortic aneurysms are usually associated with a mural thrombus through which blood continues to flow. Some early data suggest that aneurysmal…”
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Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms by Mäyränpää, Mikko I., MD, PhD, Trosien, Julia A., MSc, Fontaine, Vincent, MD, PhD, Folkesson, Maggie, MSc, Kazi, Monsur, MD, PhD, Eriksson, Per, PhD, Swedenborg, Jesper, MD, PhD, Hedin, Ulf, MD, PhD

“…Objective Mast cells (MCs) are inflammatory cells present in atherosclerotic lesions and neovascularized tissues. Recently, MCs were shown to modulate…”
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Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis by Krejci, Pavel, Masri, Bernard, Fontaine, Vincent, Mekikian, Pertchoui B, Weis, MaryAnn, Prats, Herve, Wilcox, William R

“…Overexpression of C-natriuretic peptide (CNP) in cartilage partially rescues achondroplasia in the mouse. Here, we studied the interaction of fibroblast growth…”
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Serine protease inhibitor A3 in atherosclerosis and aneurysm disease by WÅGSÄTER, DICK, JOHANSSON, DANIEL, FONTAINE, VINCENT, VORKAPIC, EMINA, BÄCKLUND, ALEXANDRA, RAZUVAEV, ANTON, MÄYRÄNPÄÄ, MIKKO I, HJERPE, CHARLOTTA, CAIDAHL, KENNETH, HAMSTEN, ANDERS, FRANCO-CERECEDA, ANDERS, WILBERTZ, JOHANNES, SWEDENBORG, JESPER, ZHOU, XINGHUA, ERIKSSON, PER

“…Remodeling of extracellular matrix (ECM) plays an important role in both atherosclerosis and aneurysm disease. Serine protease inhibitor A3 (serpinA3) is an…”
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Families of hybridized interior penalty discontinuous Galerkin methods for locally degenerate advection-diffusion-reaction problems by Etangsale, Grégory, Fahs, Marwan, Fontaine, Vincent

“…•Families of Hybridizable Interior Penalty Discontinuous Galerkin methods.•Degenerate second-order elliptic problems.•Elliptic and hyperbolic…”
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A numerical investigation on coupling of conforming and hybridizable interior penalty discontinuous Galerkin methods for fractured groundwater flow problems by Etangsale, Grégory, Fahs, Marwan, Fontaine, Vincent, Hoteit, Hussein

“…The present paper focuses on the numerical modeling of groundwater flows in fractured porous media using the codimensional model description. Therefore,…”
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Improved error estimates of hybridizable interior penalty methods using a variable penalty for highly anisotropic diffusion problems by Etangsale, Grégory, Fahs, Marwan, Fontaine, Vincent, Rajaonison, Nalitiana

“…In this paper, we derive improved a priori error estimates for families of hybridizable interior penalty discontinuous Galerkin (H-IP) methods using a variable…”
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Artificial Intelligence–Assisted Sac Diameter Assessment for Complex Endovascular Aortic Repair by Wegner, Moritz, Fontaine, Vincent, Nana, Petroula, Dieffenbach, Bryan V., Fabre, Dominique, Haulon, Stéphan

“…Purpose: Artificial intelligence (AI) using an automated, deep learning–based method, Augmented Radiology for Vascular Aneurysm (ARVA), has been verified as a…”
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Efficiency of mixed hybrid finite element and multipoint flux approximation methods on quadrangular grids and highly anisotropic media by Younes, Anis, Fontaine, Vincent

“…The mixed hybrid finite element (MHFE) and the multipoint flux approximation (MPFA) methods are well suited for anisotropic heterogeneous domains since both…”
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Abstract 15271: Modification of Cardiomyocyte Lateral Membrane Composition Promotes Cardiac Function by Regulating Connexome Organization by BLANDIN, Camille, Dilanian, Gilles, MOUGENOT, Nathalie, CHARDONNET, Solenne, HATEM, Stéphane N, Gravez, Basile jules, FONTAINE, Vincent, BOBIN, Pierre, VILLARD, Eric, BALSE, Elise

“…Abstract only Introduction: Loss of contacts between adjacent cardiomyocytes is detrimental to proper electromechanical function. For instance, connexome…”
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Characterization of Purkinje-like cardiac cells derived from iPS cells from patients with Purkinje-induced idiopathic ventricular fibrillation by Belhumeur, Pauline, Fontaine, Vincent, Surget, Elodie, Bernus, Olivier, Extramiana, Fabrice, Haissaguerre, Michel, Gandjbakhch, Estelle, Neyroud, Nathalie

“…Purkinje-induced idiopathic ventricular fibrillation (IVF), initially called short-coupled Torsades de Pointes, is a form of IVF triggered by Purkinje ectopy…”
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Performances of Hybridized-, Embedded-, and Weighted-Interior Penalty Discontinuous Galerkin Methods for Heterogeneous and Anisotropic Diffusion Problems by Etangsale, Grégory, Fontaine, Vincent, Rajaonison, Nalitiana

“…The present paper discusses families of Interior Penalty Discontinuous Galerkin (IP) methods for solving heterogeneous and anisotropic diffusion problems…”
Get full text

Performances of Hybridized-, Embedded-, and Weighted-Interior Penalty Discontinuous Galerkin Methods for Heterogeneous and Anisotropic Diffusion Problems by Etangsale, Grégory, Fontaine, Vincent, Rajaonison, Nalitiana

“…The present paper discusses families of Interior Penalty Discontinuous Galerkin (IP) methods for solving heterogeneous and anisotropic diffusion problems…”
Get full text