Search Results - "Fontaine, Jean Jacques"
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Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice
Published in Science translational medicine (16-07-2014)“…In vitro studies suggested that sub-millisecond pulses of radiation elicit less genomic instability than continuous, protracted irradiation at the same total…”
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2
Potential applications of aptamers in veterinary science
Published in Veterinary research (Paris) (02-06-2021)“…Abstract Aptamers are small nucleic acids that fold in a three-dimensional conformation allowing them to bind specifically to a target. This target can be an…”
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3
Molecular profiling of patient-derived breast cancer xenografts
Published in Breast cancer research : BCR (16-01-2012)“…Identification of new therapeutic agents for breast cancer (BC) requires preclinical models that reproduce the molecular characteristics of their respective…”
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4
Toxoplasma gondii and Alternaria sp.: An Original Association in an Immunosuppressed Dog with Persistent Skin Lesions
Published in Pathogens (Basel) (10-01-2023)“…Dogs and cats may suffer from a variety of diseases, mainly immune mediated, that require the administration of immunosuppressive drugs. Such therapies can…”
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5
Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer
Published in British journal of cancer (19-01-2016)“…Background: Oestrogen receptor-negative (ER−) breast cancer is intrinsically sensitive to chemotherapy. However, tumour response is often incomplete, and…”
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6
Subcellular Localization of Tetanus Neurotoxin-Insensitive Vesicle-Associated Membrane Protein (VAMP)/VAMP7 in Neuronal Cells: Evidence for a Novel Membrane Compartment
Published in The Journal of neuroscience (15-11-1999)“…The clostridial neurotoxin-insensitive soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptors, tetanus neurotoxin-insensitive…”
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7
Rumenic Acid Significantly Reduces Plasma Levels of LDL and Small Dense LDL Cholesterol in Hamsters Fed a Cholesterol- and Lipid-Enriched Semi-Purified Diet
Published in Lipids (01-03-2007)“…Conjugated linoleic acids (CLAs) consist of a series of positional and geometrical isomers of linoleic acid. CLA have been reported to beneficially affect…”
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8
Acquired Resistance to Endocrine Treatments Is Associated with Tumor-Specific Molecular Changes in Patient-Derived Luminal Breast Cancer Xenografts
Published in Clinical cancer research (15-08-2014)“…Patients with luminal breast cancer (LBC) often become endocrine resistant over time. We investigated the molecular changes associated with acquired…”
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9
Atypical vimentin expression in a feline salivary gland adenocarcinoma with widespread metastases
Published in Journal of Veterinary Medical Science (01-12-2009)“…We report herein a feline salivary gland adenocarcinoma with widespread metastases to draining lymph nodes, liver and lung, as well as an unusual metastasis to…”
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10
An atypical peripheral nerve sheath tumour with pseudoglandular architecture in a dog
Published in Journal of Veterinary Medical Science (01-02-2010)“…This case describes a subcutaneous soft tissue tumour in a German Shepherd dog. Histologically, the lesion was characterized by proliferating ovoid cells,…”
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11
Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patient-derived triple-negative breast cancer xenografts
Published in Molecular cancer therapeutics (01-12-2012)“…Triple-negative breast cancers (TNBC) have an aggressive phenotype with a relatively high rate of recurrence and poor overall survival. To date, there is no…”
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12
Immunohistochemical characterization of a hepatic neuroendocrine carcinoma in a cat
Published in Journal of veterinary diagnostic investigation (01-01-2008)“…Correspondence: 1 Corresponding Author: Patricia Ferreira-NevesPatricia, Ecole Nationale Vétérinaire d'Alfort, Unité d'Histologie et d'Anatomie Pathologique, 7…”
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13
Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters
Published in Laboratory investigation (01-05-2013)“…Metabolic adaptations and changes in the expression of nutrient transporters are known to accompany tumorigenic processes. Nevertheless, in the context of…”
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14
A mammary gland adenomyoepithelioma in a C57BL/6 mouse
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01-08-2008)“…Mammary gland adenomyoepitheliomas are benign complex mammary gland tumors composed of neoplastic cells of epithelial and myoepithelial origins, described in…”
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15
BSE agent signatures in a goat
Published in Veterinary record (16-04-2005)Get full text
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16
Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals ( Phoca vitulina)
Published in Veterinary microbiology (28-09-2010)“…The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize…”
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Preclinical assessment of cisplatin-based therapy versus docetaxel-based therapy on a panel of human non-small-cell lung cancer xenografts
Published in Anti-cancer drugs (01-11-2009)“…The success of treatment of advanced non-small-cell lung cancer (NSCLC) remains very poor. The aim of this study was, on a series of NSCLC xenografts, to…”
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18
In vivo, Villin Is Required for Ca2+-Dependent F-Actin Disruption in Intestinal Brush Borders
Published in The Journal of cell biology (23-08-1999)“…Villin is an actin-binding protein localized in intestinal and kidney brush borders. In vitro, villin has been demonstrated to bundle and sever F-actin in a…”
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A preclinical therapeutic schedule optimizing docetaxel plus estramustine administration in prostate cancer
Published in Anti-cancer drugs (01-11-2010)“…Androgen-dependent and castration-resistant prostate cancer (PC) is usually sensitive to docetaxel chemotherapy. Nevertheless, docetaxel resistance frequently…”
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Microcystin-LR and embryo–larval development of medaka fish, Oryzias latipes. I. Effects on the digestive tract and associated systems
Published in Toxicon (Oxford) (01-07-2005)“…The cyanobacterial hepatotoxin microcystin-LR (MC-LR) is a specific potent PP1 and PP2A protein phosphatase inhibitor. In view to obtain an integrated…”
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