Search Results - "Fonseca, Mario A"
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Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome
Published in The Journal of physiology (15-07-2015)“…Key points Gestational diabetes mellitus is a common complication of pregnancy, but its effects on the offspring are poorly understood. We developed a rat…”
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Integrative analysis reveals novel associations between DNA methylation and the serum metabolome of adolescents with type 2 diabetes: A cross-sectional study
Published in Frontiers in endocrinology (Lausanne) (10-10-2022)“…Objective Rates of type 2 diabetes (T2D) among adolescents are on the rise. Epigenetic changes could be associated with the metabolic alterations in…”
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3
DNA methylation signatures of youth-onset type 2 diabetes and exposure to maternal diabetes
Published in Clinical epigenetics (13-05-2024)“…Youth-onset type 2 diabetes (T2D) is physiologically distinct from adult-onset, but it is not clear how the two diseases differ at a molecular level. In utero…”
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4
Adiponectin deficiency induces hepatic steatosis during pregnancy and gestational diabetes in mice
Published in Diabetologia (01-04-2022)“…Aims/hypothesis Obesity and hepatic steatosis are risk factors for gestational diabetes mellitus (GDM), a common complication of pregnancy. Adiponectin is a…”
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Maternal resveratrol administration protects against gestational diabetes‐induced glucose intolerance and islet dysfunction in the rat offspring
Published in The Journal of physiology (01-08-2019)“…Key points Maternal resveratrol (RESV) administration in gestational diabetes (GDM) restored normoglycaemia and insulin secretion. GDM‐induced obesity was…”
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Gestational Diabetes Adversely Affects Pancreatic Islet Architecture and Function in the Male Rat Offspring
Published in Endocrinology (Philadelphia) (01-08-2019)“…Abstract Fetal exposure to gestational diabetes mellitus (GDM) and poor postnatal diet are strong risk factors for type 2 diabetes development later in life,…”
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Adiponectin Deficiency Contributes to the Development of Gestational Diabetes Mellitus
Published in Canadian journal of diabetes (01-10-2014)Get full text
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8
Early Life Development of Cardiac Hypertrophy in Rat Offspring from Pregnancies Complicated by Gestational Diabetes Mellitus
Published in Canadian journal of diabetes (01-10-2013)Get full text
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Altered Fatty Acid and Mitochondrial Metabolism in the Liver of Pregnant Adiponectin‐Deficient Mice Contributes to Insulin Resistance and Gestational Diabetes Mellitus
Published in The FASEB journal (01-04-2017)“…Abstract only Introduction Gestational diabetes mellitus (GDM) is a common pregnancy‐related health condition. While genetics, lifestyle and diet contribute to…”
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Abstract 15820: Exposure to Gestational Diabetes Alters Cardiac Gene Expression and Metabolism in the Rat Offspring and Induces Cardiac Dysfunction With Age
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionGestational diabetes mellitus (GDM) is the most common complication of pregnancy. Children exposed to GDM are at an increased risk for the…”
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A GENERAL EQUILIBRIUM MODEL FOR THE INCIDENCE OF THE PAYROLL TAX
Published 01-01-1981“…A static, general equilibrium model of the U.S. economy with a number of consumer groups and industrial sectors is built to analyze the incidence of the…”
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Dissertation