Search Results - "Fonseca, Danae"

TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment by Fonseca, Danae, Pisanelli, Giuseppe, Seoane, Rocío, Miorin, Lisa, García-Sastre, Adolfo

“…Viral infection triggers a rapid and effective cellular response primarily mediated by interferon β (IFNβ), which induces an antiviral state through complex…”
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eIF5A is activated by virus infection or dsRNA and facilitates virus replication through modulation of interferon production by Seoane, Rocío, Llamas-González, Yessica Y., Vidal, Santiago, El Motiam, Ahmed, Bouzaher, Yanis Hichem, Fonseca, Danae, Farrás, Rosa, García-Sastre, Adolfo, González-Santamaría, José, Rivas, Carmen

“…Active hypusine-modified initiation elongation factor 5A is critical for cell proliferation and differentiation, embryonic development, and innate immune…”
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BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II by Kleiman, Frida E, Wu-Baer, Foon, Fonseca, Danae, Kaneko, Syuzo, Baer, Richard, Manley, James L

“…Mammalian cells exhibit a complex response to DNA damage. The tumor suppressor BRCA1 and associated protein BARD1 are thought to play an important role in this…”
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DNA damage-induced BARD1 phosphorylation is critical for the inhibition of messenger RNA processing by BRCA1/BARD1 complex by KIM, Ho-Shik, HONGJIE LI, CEVHER, Murat, PARMELEE, Alissa, FONSECA, Danae, KLEIMAN, Frida Esther, SEAN BONG LEE

“…BRCA1-associated RING domain protein BARD1, along with its heterodimeric partner BRCA1, plays important roles in cellular response to DNA damage. Immediate…”
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mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response by Fonseca, Danae, Baquero, Jorge, Murphy, Michael R., Aruggoda, Gamage, Varriano, Sophia, Sapienza, Carmen, Mashadova, Oksana, Rahman, Shadaqur, Kleiman, Frida E.

“…The cellular response to DNA damage is an intricate mechanism that involves the interplay among several pathways. In this study, we provide evidence of the…”
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Role of the Polyadenylation Factor CstF-50 in regulating the BRCA1/BARD1 E3 Ubiquitin (Ub) Ligase Activity by Fonseca, Danae

“…The cellular response to DNA damage is an intricate mechanism that involves the interplay among several pathways. The studies presented in this dissertation…”
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3' processing factor CstF functions in the DNA repair response by Mirkin, Nurit, Fonseca, Danae, Mohammed, Samia, Cevher, Murat A, Manley, James L, Kleiman, Frida E

“…Following DNA damage, mRNA levels decrease, reflecting a coordinated interaction of the DNA repair, transcription and RNA processing machineries. In this…”
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