Search Results - "Fonseca, Ayden"

Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19 by Tindle, Courtney, Fuller, MacKenzie, Fonseca, Ayden, Taheri, Sahar, Ibeawuchi, Stella-Rita, Beutler, Nathan, Katkar, Gajanan Dattatray, Claire, Amanraj, Castillo, Vanessa, Hernandez, Moises, Russo, Hana, Duran, Jason, Crotty Alexander, Laura E, Tipps, Ann, Lin, Grace, Thistlethwaite, Patricia A, Chattopadhyay, Ranajoy, Rogers, Thomas F, Sahoo, Debashis, Ghosh, Pradipta, Das, Soumita

“…SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains…”
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COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis by Sinha, Saptarshi, Castillo, Vanessa, Espinoza, Celia R., Tindle, Courtney, Fonseca, Ayden G., Dan, Jennifer M., Katkar, Gajanan D., Das, Soumita, Sahoo, Debashis, Ghosh, Pradipta

“…In the aftermath of Covid-19, some patients develop a fibrotic lung disease, i.e., post-COVID-19 lung disease (PCLD), for which we currently lack insights into…”
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E-cigarettes compromise the gut barrier and trigger inflammation by Sharma, Aditi, Lee, Jasper, Fonseca, Ayden G., Moshensky, Alex, Kothari, Taha, Sayed, Ibrahim M., Ibeawuchi, Stella-Rita, Pranadinata, Rama F., Ear, Jason, Sahoo, Debashis, Crotty-Alexander, Laura E., Ghosh, Pradipta, Das, Soumita

“…E-cigarette usage continues to rise, yet the safety of e-cigarette aerosols is questioned. Using murine models of acute and chronic e-cigarette aerosol…”
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Functional assays with human patient-derived enteroid monolayers to assess the human gut barrier by Sayed, Ibrahim M., Tindle, Courtney, Fonseca, Ayden G., Ghosh, Pradipta, Das, Soumita

“…Here, we describe the use of polarized patient enteroid-derived monolayers (EDMs) to assess the impact of e-cigarettes on the human gut barrier. These EDMs can…”
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A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics by Tindle, Courtney, Fonseca, Ayden G., Taheri, Sahar, Katkar, Gajanan D., Lee, Jasper, Maity, Priti, Sayed, Ibrahim M., Ibeawuchi, Stella-Rita, Vidales, Eleadah, Pranadinata, Rama F., Fuller, Mackenzie, Stec, Dominik L., Anandachar, Mahitha Shree, Perry, Kevin, Le, Helen N., Ear, Jason, Boland, Brigid S., Sandborn, William J., Sahoo, Debashis, Das, Soumita, Ghosh, Pradipta

“…Crohn’s disease (CD) is a complex and heterogeneous condition with no perfect preclinical model or cure. To address this, we explore adult stem cell-derived…”
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A Prospectively Created Living Organoid Biobank of Crohn’s Disease Patients Enables Integrative Therapeutics by Katkar, Gajanan Dattatray, Tindle, Courtney, Fonseca, Ayden, Taheri, Sahar, Lee, Jasper, Sayed, Ibrahim M., Ibeawuchi, Stella-Rita, Rama, Pranadinata, Fuller, Mackenzie, Stec, Dominik, Anandachar, Mahitha Shree, Goheen-Holland, Vanae, Ear, Jason, Boland, Brigid, Sandborn, William, Sahoo, Debashis, Das, Soumita, Ghosh, Pradipta

“…Abstract Adult stem cells from various organs can be propagated as epithelial organoids that not only retain their tissue identity, but also their genetic and…”
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