Search Results - "Fons, Michael"

Tolerability of Two Sequential Electroporation Treatments Using MedPulser DNA Delivery System (DDS) in Healthy Adults by Wallace, Mark, Evans, Barbara, Woods, Sandra, Mogg, Robin, Zhang, Lei, Finnefrock, Adam C, Rabussay, Dietmar, Fons, Michael, Mallee, John, Mehrotra, Devan, Schödel, Florian, Musey, Luwy

“…Immunotherapy against infectious agents and malignant tumors requires efficient priming of effector cells through direct expression and/or efficient…”
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Piezoelectric permeabilization of mammalian dermal tissue for in vivo DNA delivery leads to enhanced protein expression and increased immunogenicity by Broderick, Kate E., Kardos, Thomas, McCoy, Jay R., Fons, Michael P., Kemmerrer, Stephen, Sardesai, Niranjan Y.

“…Electropermeabilization of mammalian cells is a technique that has been used for the delivery of therapeutics, such as DNA plasmids or DNA vaccines. Typically,…”
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Nickel potentiates the genotoxic effect of benzo[a]pyrene in Chinese hamster lung V79 cells by Deng, Cheng Z., Fons, Michael P., Rosenblatt, Judah, El-Zein, Randa A., Abdel-Rahman, Sherif Z., Albrecht, Thomas

“…The modulating effect of acute exposure to NiCl2 on the induction of chromosome aberrations by a model carcinogen, benzo[a]pyrene (B[a]P), was examined in…”
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Subtle Manipulation: A Rhetorical Analysis of Medea Across Time and Genre in Greek and Roman Literature by Fons, Michael

“…This thesis focuses on the character of Medea, analyzing her ability to adapt her rhetoric across genre and time period. Specifically, I will look at Medea’s…”
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Therapeutic DNA Vaccination Using In Vivo Electroporation Followed by Standard of Care Therapy in Patients With Genotype 1 Chronic Hepatitis C by Weiland, Ola, Ahlén, Gustaf, Diepolder, Helmut, Jung, Maria-Christina, Levander, Sepideh, Fons, Michael, Mathiesen, Iacob, Sardesai, Niranjan Y, Vahlne, Anders, Frelin, Lars, Sällberg, Matti

“…Clearance of infections caused by the hepatitis C virus (HCV) correlates with HCV-specific T cell function. We therefore evaluated therapeutic vaccination in…”
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In Vivo Electroporation Enhances the Immunogenicity of Hepatitis C Virus Nonstructural 3/4A DNA by Increased Local DNA Uptake, Protein Expression, Inflammation, and Infiltration of CD3+ T Cells by Ahlen, Gustaf, Soderholm, Jonas, Tjelle, Torunn, Kjeken, Rune, Frelin, Lars, Hoglund, Urban, Blomberg, Pontus, Fons, Michael, Mathiesen, Iacob, Sallberg, Matti

“…The mechanisms by which in vivo electroporation (EP) improves the potency of i.m. DNA vaccination were characterized by using the hepatitis C virus…”
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Receptor-Initiated Activation of Cells and Their Oncogenes by Herpes-Family Viruses by Albrecht, Thomas, Boldogh, Istvan, Fons, Michael P

“…The interaction of human cytomegalovirus (HCMV) with the cell membrane has been shown to initiate a cascade of physiologic and biochemical responses that…”
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Multiple herpesviruses in saliva of HIV-infected individuals by Fons, M P, Flaitz, C M, Moore, B, Prabhakar, B S, Nichols, C M, Albrecht, T

“…Oral infections with human herpesviruses cause increased morbidity in patients infected with HIV. In this study, multiple HHVs were often isolated from the…”
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Improving on the Ability of Endogenous Hepatitis B Core Antigen to Prime Cytotoxic T Lymphocytes by Nystroöm, Jessica, Chen, Antony, Frelin, Lars, Ahlén, Gustaf, Koh, Sarene, Brass, Anette, Peterson, Darrell L., Fons, Michael, Milich, David R., Hultgren, Catharina, Sällberg, Matti

“…Hepatitis B virus core antigen (HBcAg) is thought to be a major target for specific cytotoxic T cells (CTLs) in hepatitis B virus infections. A single dose of…”
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In Vivo Electroporation Enhances the Immunogenicity of Hepatitis C Virus Nonstructural 3/4A DNA by Increased Local DNA Uptake, Protein Expression, Inflammation, and Infiltration of CD3 super(+) T Cells by Ahlen, Gustaf, Soederholm, Jonas, Tjelle, Torunn, Kjeken, Rune, Frelin, Lars, Hoeglund, Urban, Blomberg, Pontus, Fons, Michael, Mathiesen, Iacob, Saellberg, Matti

“…The mechanisms by which in vivo electroporation (EP) improves the potency of i.m. DNA vaccination were characterized by using the hepatitis C virus…”
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Modulation of the frequency of human cytomegalovirus-induced chromosome aberrations by camptothecin by Deng, C Z, AbuBakar, S, Fons, M P, Boldogh, I, Albrecht, T

“…The effects of selected DNA repair inhibitors on the frequency of human cytomegalovirus (HCMV)-induced chromosome aberrations were evaluated in human…”
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Preface by Fons, Michael P.

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Gene-based vaccines by FONS, Michael P

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Differential mutagen sensitivity of peripheral blood lymphocytes from smokers and nonsmokers: Effect of human cytomegalovirus infection by Albrecht, Thomas, Deng, Cheng Zong, Abdel-Rahman, Sherif Z., Fons, Michael, Cinciripini, Paul, El-Zein, Randa A.

“…We used the mutagen sensitivity assay to test the hypothesis that human cytomegalovirus (HCMV) infection modifies the sensitivity of cells to genetic damage…”
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The Intellectual Property Landscape in the Field of Plasmid-Based Gene Therapy by Fons, Michael P.

“…Abstract As plasmid-based gene therapy products progress through clinical trials commercial entities begin to focus on the intellectual property associated…”
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Increased Frequency of Specific Locus Mutation Following Human Cytomegalovirus Infection by Albrecht, Thomas, Fons, Michael P., Deng, Cheng Z., Boldogh, Istvan

“…The effect of human cytomegalovirus (HCMV) infection on the frequency of mutations at the hypoxanthine-guanine phosphoribosyl transferase (hprt) locus was…”
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Human cytomegalovirus infection increases the number of ouabain-binding sites in human fibroblasts by Altamirano, A A, Fons, M P, Russell, J M, Cragoe, Jr, E J, Albrecht, T

“…Infection of permissive human embryo fibroblasts (MRC-5) with human cytomegalovirus (HCMV) increased the number of copies of the Na+,K(+)-ATPase (the Na+ pump)…”
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Mean Value Engine Modelling of an SI Engine with EGR by Fons, Michael, Muller, Martin, Chevalier, Alain, Vigild, Christian, Hendricks, Elbert, Sorenson, Spencer C.

“…Mean Value Engine Models (MVEMs) are simplified, dynamic engine models which are physically based. Such models are useful for control studies, for engine…”
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