Search Results - "Fongaro, Benedetta"
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Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC
Published in International journal of molecular sciences (02-06-2021)“…The interplay between α-synuclein and dopamine derivatives is associated with oxidative stress-dependent neurodegeneration in Parkinson’s disease (PD). The…”
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Biodiversity and Bioprospecting of Fungal Endophytes from the Antarctic Plant Colobanthus quitensis
Published in Journal of fungi (Basel) (19-09-2022)“…Microorganisms from extreme environments are considered as a new and valuable reservoir of bioactive molecules of biotechnological interest and are also…”
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Environmental Signals Act as a Driving Force for Metabolic and Defense Responses in the Antarctic Plant Colobanthus quitensis
Published in Plants (Basel) (21-11-2022)“…During evolution, plants have faced countless stresses of both biotic and abiotic nature developing very effective mechanisms able to perceive and counteract…”
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Light exacerbates local and global effects induced by pH unfolding of Ipilimumab
Published in European journal of pharmaceutics and biopharmaceutics (01-08-2024)“…[Display omitted] Monoclonal antibodies (mAbs) are an essential class of therapeutic proteins for the treatment of cancer, autoimmune and rare diseases. During…”
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Managing antibody stability: Effects of stressors on Ipilimumab from the commercial formulation to diluted solutions
Published in European journal of pharmaceutics and biopharmaceutics (01-07-2022)“…[Display omitted] The stability of the monoclonal antibody Ipilimumab, the active ingredient of Yervoy®, used for the treatment of different types of cancer,…”
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Catechol-induced covalent modifications modulate the aggregation tendency of α-synuclein: An in-solution and in-silico study
Published in BioFactors (Oxford) (27-05-2024)“…Parkinson's disease (PD) stands as a challenging neurodegenerative condition characterized by the emergence of Lewy Bodies (LBs), intracellular inclusions…”
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3,4‐Dihydroxyphenylethanol and 3,4‐dihydroxyphenylacetic acid affect the aggregation process of E46K variant of α‐synuclein at different extent: Insights into the interplay between protein dynamics and catechol effect
Published in Protein science (01-07-2022)“…Parkinson's disease (PD) is a chronic multifactorial disease, whose etiology is not completely understood. The amyloid aggregation of α‐synuclein (Syn) is…”
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Assessing the physicochemical stability and intracellular trafficking of mRNA-based COVID-19 vaccines
Published in International journal of pharmaceutics (25-09-2023)“…[Display omitted] The emergence of SARS-CoV-2 in Wuhan, China in 2019 has had a profound impact on humanity in every facet. While vaccines against this viral…”
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Environmental Signals Act as a Driving Force for Metabolic and Defense Responses in the Antarctic Plant IColobanthus quitensis/I
Published in Plants (Basel) (01-11-2022)Get full text
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