Search Results - "Folorunso, Ibukun Mary"

Repurposing clinically approved drugs as Wee1 checkpoint kinase inhibitors: an in silico investigation integrating molecular docking, ensemble QSAR modelling and molecular dynamics simulation by Olawale, Femi, Ogunyemi, Oludare, Folorunso, Ibukun Mary

“…High levels of Wee1 expression have been seen in a variety of malignancies, including breast cancer, cervical cancer and leukaemia. Due to the positive link…”
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Morin hydrate promotes nephrin expression through modulation of Notch1-Snail signalling pathway in diabetic rats by Lawal, Akeem Olalekan, Folorunso, Ibukun Mary, Adebisi, Olufemi, Koledoye, Omowumi Funmilayo, Iwaloye, Opeyemi

“…Reduction in nephrin expression is usually observed in patients with diabetic nephropathy, and there is evidence that Notch1/Snail signalling pathway is…”
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Computer-aided drug design in anti-cancer drug discovery: What have we learnt and what is the way forward? by Iwaloye, Opeyemi, Ottu, Paul Olamide, Olawale, Femi, Babalola, Olorunfemi Oyewole, Elekofehinti, Olusola Olalekan, Kikiowo, Babatomiwa, Adegboyega, Abayomi Emmanuel, Ogbonna, Henry Nnaemeka, Adeboboye, Covenant Femi, Folorunso, Ibukun Mary, Fakayode, Aderonke Elizabeth, Akinjiyan, Moses Orimoloye, Onikanni, Sunday Amos, Shityakov, Sergey

“…The escalating prevalence of cancer on a global scale, coupled with the inadequacies of present-day therapies and the emergence of drug-resistant cancer…”
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Newly designed compounds from scaffolds of known actives as inhibitors of survivin: computational analysis from the perspective of fragment-based drug design by Elekofehinti, Olusola Olalekan, Iwaloye, Opeyemi, Olawale, Femi, Chukwuemeka, Prosper Obed, Folorunso, Ibukun Mary

“…Survivin is an apoptosis suppressing protein linked to different forms of cancer. As it stands, there are no approved drugs for the inhibition of survivin in…”
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Hepatoprotective Effect of Morin Hydrate in Type 2 Diabetic Wistar Rats Exposed to Diesel Exhaust Particles by Folorunso, Ibukun Mary, Lawal, Akeem Olalekan, Elekofehinti, Olusola Olalekan, Iwaloye, Opeyemi

“…Studies have shown that exposure to air pollutants such as diesel exhaust particles (DEP) exacerbate diabetes complications. Morin hydrate (MH), a plant…”
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Effects of Bryophyllum pinnatum on Dysfunctional Autophagy in Rats Lungs Exposed to Zinc Oxide Nanoparticles by Ijatuyi, Taiwo Tolulope, Lawal, Akeem Olalekan, Akinjiyan, Moses Orimoloye, Ojo, Funmilayo Mercy, Koledoye, Omowumi Funmilayo, Agboola, Olaoluwa Oladimeji, Dahunsi, Damilola Timothy, Folorunso, Ibukun Mary, Elekofehinti, Olusola Olalekan

“…[Display omitted] •Zinc oxide nanoparticles were able to cause pulmonary dysfunction in Wistar rats.•Bryophyllum pinnatum increased antioxidant activities and…”
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The therapeutic value of alstonine: An updated review by Olawale, Femi, Adetunji, Tomi Lois, Adetunji, Ademola Emmanuel, Iwaloye, Opeyemi, Folorunso, Ibukun Mary

“…•Alstonine is an indole alkaloid found abundantly in some traditional plants.•Alstonine has chemotherapeutic properties by acting as an intercalating agent and…”
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Anacardium occidentale leaves extract and riboceine mitigate hyperglycemia through anti-oxidative effects and modulation of some selected genes associated with diabetes by Ukwenya, Victor Okoliko, Alese, Margaret Olutayo, Ogunlade, Babatunde, Folorunso, Ibukun Mary, Omotuyi, Olaposi Idowu

“…Background Diabetes mellitus (DM) is one of the leading causes of death globally and complications of DM have become a major health concern. Anacardium…”
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