Search Results - "Follis, Kathryn E"

Prevention of SIV Infection in Macaques by (R)-9-(2-Phosphonylmethoxypropyl)adenine by Tsai, Che-Chung, Follis, Kathryn E., Sabo, Alexander, Beck, Thomas W., Grant, Richard F., Bischofberger, Norbert, Benveniste, Raoul E., Black, Roberta

“…The efficacy of pre- and postexposure treatment with the antiviral compound (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) was tested against simian…”
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Genetic Evidence that Interhelical Packing Interactions in the gp41 Core Are Critical for Transition of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein to the Fusion-Active State by Follis, Kathryn E, Larson, Scott J, Lu, Min, Nunberg, Jack H

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Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell–cell fusion but does not affect virion entry by Follis, Kathryn E., York, Joanne, Nunberg, Jack H.

“…The fusogenic potential of Class I viral envelope glycoproteins is activated by proteloytic cleavage of the precursor glycoprotein to generate the mature…”
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Effectiveness of Postinoculation (R)-9-(2-Phosphonylmethoxypropyl)Adenine Treatment for Prevention of Persistent Simian Immunodeficiency Virus SIVmne Infection Depends Critically on Timing of Initiation and Duration of Treatment by Tsai, C C, Emau, P, Follis, K E, Beck, T W, Benveniste, R E, Bischofberger, N, Lifson, J D, Morton, W R

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Fusion-Competent Vaccines: Broad Neutralization of Primary Isolates of HIV by LaCasse, Rachel A., Follis, Kathryn E., Trahey, Meg, Scarborough, John D., Littman, Dan R., Nunberg, Jack H.

“…Current recombinant human immunodeficiency virus (HIV) gp120 protein vaccine candidates are unable to elicit antibodies capable of neutralizing infectivity of…”
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Serine-scanning mutagenesis studies of the C-terminal heptad repeats in the SARS coronavirus S glycoprotein highlight the important role of the short helical region by Follis, Kathryn E., York, Joanne, Nunberg, Jack H.

“…The fusion subunit of the SARS-CoV S glycoprotein contains two regions of hydrophobic heptad-repeat amino acid sequences that have been shown in biophysical…”
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Antibody Binding and Neutralization of Primary and T-Cell Line-Adapted Isolates of Human Immunodeficiency Virus Type 1 by York, J, Follis, K E, Trahey, M, Nyambi, P N, Zolla-Pazner, S, Nunberg, J H

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Evidence for a polytopic form of the E1 envelope glycoprotein of Hepatitis C virus by Migliaccio, Christopher T., Follis, Kathryn E., Matsuura, Yoshiharu, Nunberg, Jack H.

“…The polyprotein precursor of the Hepatitis C virus (HCV) contains multiple membrane-spanning domains that define the membrane topology and subsequent…”
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Coreceptor Utilization by Human Immunodeficiency Virus Type 1 Is Not a Primary Determinant of Neutralization Sensitivity by LaCasse, R A, Follis, K E, Moudgil, T, Trahey, M, Binley, J M, Planelles, V, Zolla-Pazner, S, Nunberg, J H

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Turning a corner on HIV neutralization? by Nunberg, Jack H, Follis, Kathryn E, Trahey, Meg, LaCasse, Rachel A

“…HIV vaccine development has been hampered by the inability of conventional immunogens to elicit antibodies capable of neutralizing primary isolates of the…”
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Continued Utilization of CCR5 Coreceptor by a Newly Derived T-Cell Line-Adapted Isolate of Human Immunodeficiency Virus Type 1 by Follis, K E, Trahey, M, LaCasse, R A, Nunberg, J H

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Effect of dosing frequency on ZDV prophylaxis in macaques infected with simian immunodeficiency virus by Tsai, C C, Follis, K E, Grant, R F, Nolte, R E, Bartz, C R, Benveniste, R E, Sager, P R

“…The effect of dosing frequency on zidovudine (ZDV) prophylaxis against simian immunodeficiency virus (SIV) infection was examined in long-tailed macaque…”
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Comparison of the efficacy of AZT and PMEA treatment against acute SIVmne infection in macaques by Tsai, C C, Follis, K E, Grant, R, Sabo, A, Nolte, R, Bartz, C, Bischofberger, N, Benveniste, R

“…The antiretroviral drugs azidothymidine (AZT) and 9-(-2-phosphonyl-methoxyethyl)adenine (PMEA) were individually tested for prevention of simian…”
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Antiviral effects of 3'-azido-3'-deoxythymidine, 2',3'-dideoxycytidine, and 2',3'-dideoxyadenosine against simian acquired immunodeficiency syndrome-associated type D retrovirus in vitro by Tsai, C C, Follis, K E, Benveniste, R E

“…The simian acquired immunodeficiency syndrome (SAIDS) in macaques at the Washington Regional Primate Research Center is associated with a type D retrovirus…”
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Effects of (R)-9-(2-phosphonylmethoxypropyl)adenine monotherapy on chronic SIV infection in macaques by Tsai, C C, Follis, K E, Beck, T W, Sabo, A, Bischofberger, N, Dailey, P J

“…(R)-9-(2-Phosphonylmethoxypropyl)adenine (PMPA) acts as a reverse transcriptase inhibitor of retroviruses and has been shown to be effective against acute…”
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Efficacy of 9-(2-Phosphonylmethoxyethyl)adenine Treatment against Chronic Simian Immunodeficiency Virus Infection in Macaques by Tsai, Che-Chung, Follis, Kathryn E., Sabo, Alexander, Grant, Richard, Bischofberger, Norbert

“…Long-tailed macaques chronically infected with simian immunodeficiency virus (SIV) were treated for 4 or 8 weeks with daily subcutaneous doses of the…”
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Effectiveness of Postinoculation ( R )-9-(2-Phosphonylmethoxypropyl)Adenine Treatment for Prevention of Persistent Simian Immunodeficiency Virus SIV mne Infection Depends Critically on Timing of Initiation and Duration of Treatment by Tsai, Che-Chung, Emau, Peter, Follis, Kathryn E., Beck, Thomas W., Benveniste, Raoul E., Bischofberger, Norbert, Lifson, Jeffrey D., Morton, William R.

“…( R )-9-(2-Phosphonylmethoxypropyl)adenine (PMPA), an acyclic nucleoside phosphonate analog, is one of a new class of potent antiretroviral agents. Previously,…”
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Preexposure Prophylaxis with 9-(2-Phosphonylmethoxyethyl)adenine against Simian Immunodeficiency Virus Infection in Macaques by Tsai, Che-Chung, Follis, Kathryn E., Sabo, Alexander, Grant, Richard F., Bartz, Curtis, Nolte, Randolph E., Benveniste, Raoul E., Bischofberger, Norbert

“…A reverse transcriptase inhibitor, 9-(2-phosphonylmethoxyethyl)adenine (PMEA), was evaluated for efficacy against acute simian immunodeficiency virus (SIV)…”
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Post-exposure chemoprophylaxis (PECP) against SIV infection of macaques as a model for protection from HIV infection by Tsai, Che-Chung, Emau, Peter, Sun, Joseph C., Beck, Thomas W., Tran, Chy-Anh, Follis, Kathryn E., Bischofberger, Norbert, Morton, William R.

“…We report that simian immunodeficiency virus (SIV) infection in macaques is a valuable animal model for studying post‐exposure chemoprophylaxis (PECP). PECP…”
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Prevention of SIV infection in macaques by adenine.(simian immunodeficiency virus) by Tsai, Che-Chung, Follis, Kathryn E, Sabo, Alexander, Beck, Thomas W, Grant, Richard F, Bischofberger, Norbert, Benveniste, Raoul E, Black, Roberta

“…The efficacy of pre- and postexposure treatment with the antiviral compound (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) was tested against simian…”
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